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Genetic oscillators are a major theme of interest in the emerging field of synthetic biology. Until recently, most work has been carried out using intra-cellular oscillators, but this approach restricts the broader applicability of such…

Cell Behavior · Quantitative Biology 2010-07-28 Angel Goni-Moreno , Martyn Amos

Maintenance of plasma IgM levels is critical for immune system function and homeostasis in humans and mice. However, the mechanisms that control homeostasis of the activated IgM-secreting B cells are unknown. After adoptive transfer into…

Microresonators are micron-scale optical systems that confine light using total internal reflection. These optical systems have gained interest in the last two decades due to their compact sizes, unprecedented measurement capabilities, and…

We developed a powerful computational approach to elaborate on onset mechanisms of deterministic chaos due to complex homoclinic bifurcations in diverse systems. Its core is the reduction of phase space dynamics to symbolic binary…

Chaotic Dynamics · Physics 2018-11-07 Krishna Pusuluri , Andrey L Shilnikov

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Spatio-temporal bifurcations and complex dynamics in globally coupled intrinsically bistable electrochemical systems with an S-shaped current-voltage characteristic under galvanostatic control are studied theoretically on a one-dimensional…

Pattern Formation and Solitons · Physics 2016-08-16 F. Plenge , P. Rodin , E. Schöll , K. Krischer

An rf superconducting quantum interference device (SQUID) consists of a superconducting ring interrupted by a Josephson junction (JJ). When driven by an alternating magnetic field, the induced supercurrents around the ring are determined by…

Chaotic Dynamics · Physics 2024-01-26 M. Agaoglou , V. M. Rothos , H. Susanto

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

We study bifurcation behavior in periodic perturbations of two-dimensional symmetric systems exhibiting codimension-two bifurcations with a double eigenvalue when the frequencies of the perturbation terms are small. We transform the…

Dynamical Systems · Mathematics 2023-02-15 Kazuyuki Yagasaki

Recent experiments have shown that the spontaneous activity of young dissociated neuronal cultures can be described as a process of highly inhomogeneous nucleation and front propagation due to the localization of noise activity, i.e., noise…

Neurons and Cognition · Quantitative Biology 2021-05-26 Javier G. Orlandi , Jaume Casademunt

A method of controlling Shil'nikov's type chaos using windows that appear in the 1 dimensional bifurcation diagram when perturbations are applied, and using existence of stable homoclinic orbits near the unstable one is presented and…

Chaotic Dynamics · Physics 2015-06-26 Sadataka Furui , Shohei Niiya

Motivated by a stochastic differential equation describing the dynamics of interfaces, we study the bifurcation behavior of a more general class of such equations. These equations are characterized by a 2-dimensional phase space (describing…

Chaotic Dynamics · Physics 2012-04-11 Stewart E. Barnes , Jean-Pierre Eckmann , Thierry Giamarchi , Vivien Lecomte

We present a framework for analyzing luminescence regulation during quorum sensing in the bioluminescent bacterium \emph{Vibrio harveyi}. Using a simplified model for signal transduction in the quorum sensing pathway, we identify key…

Cell Behavior · Quantitative Biology 2009-10-22 Suman K Banik , Andrew T Fenley , Rahul V Kulkarni

This work describes a collective decision-making dynamical process in a multiagent system under the assumption of cooperative higher-order interactions within the community, modeled as a hypernetwork. The nonlinear interconnected system is…

Optimization and Control · Mathematics 2025-09-08 Angela Fontan , Silun Zhang

We develop a formalism to describe the discrete-time dynamics of systems containing an arbitrary number of interacting species. The individual-based model, which forms our starting point, is described by a Markov chain, which in the limit…

Statistical Mechanics · Physics 2014-10-06 César Parra-Rojas , Joseph D. Challenger , Duccio Fanelli , Alan J. McKane

Cooperative effects in neural networks appear because a neuron fires only if a minimal number $m$ of its inputs are excited. The multiple inputs requirement leads to a percolation model termed {\it quorum percolation}. The connectivity…

Disordered Systems and Neural Networks · Physics 2010-07-30 Or Cohen , Anna Keselman , Elisha Moses , María Rodríguez Martínez , Jordi Soriano , Tsvi Tlusty

Complex contagion models that involve contagion along higher-order structures, such as simplicial complexes and hypergraphs, yield new classes of mean-field models. Interestingly, the differential equations arising from many such models…

Physics and Society · Physics 2025-09-24 István Z. Kiss , Christian Bick , Péter L. Simon

Quorum sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-sensing proteins should contribute strongly to understanding…

Quantitative Methods · Quantitative Biology 2015-05-14 Shu-Wen Teng , Yufang Wang , Kimberly C. Tu , Tao Long , Pankaj Mehta , Ned S. Wingreen , Bonnie L. Bassler , N. P. Ong

We explore the critical behaviors in the dynamics of information transfer of a biologically-inspired system by an individual-based model. "Quorum response", a type of social interaction which has been recognized taxonomically in animal…

Physics and Society · Physics 2013-08-22 Collin Feng Hu

We consider an opinion dynamics model coupled with an environmental dynamics. Based on a forward invariance argument, we can simplify the analysis of the asymptotic behavior to the case when all the opinions in the social network are…

Systems and Control · Electrical Eng. & Systems 2025-04-07 Anthony Couthures , Anastasia Bizyaeva , Vineeth S. Varma , Alessio Franci , Irinel-Constantin Morarescu