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Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g. hallucinations and delusions), using two distinct channel-delay correlation methods. We show that the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-18 Yashish M. Siriwardena , Chris Kitchen , Deanna L. Kelly , Carol Espy-Wilson

In recent years, convolutional neural networks (CNNs) with channel-wise feature refining mechanisms have brought noticeable benefits to modelling channel dependencies. However, current attention paradigms fail to infer an optimal channel…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Nick Nikzad , Yongsheng Gao , Jun Zhou

Multiple sclerosis (MS) affects the central nervous system with a wide range of symptoms. MS can, for example, cause pain, changes in mood and fatigue, and may impair a person's movement, speech and visual functions. Diagnosis of MS…

Computers and Society · Computer Science 2020-12-03 Patrick Schwab , Walter Karlen

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

Independent component analysis (ICA) of multi-subject functional magnetic resonance imaging (fMRI) data has proven useful in providing a fully multivariate summary that can be used for multiple purposes. ICA can identify patterns that can…

Neurons and Cognition · Quantitative Biology 2022-11-15 Fateme Ghayem , Hanlu Yang , Furkan Kantar , Seung-Jun Kim , Vince D. Calhoun , Tulay Adali

As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Usman Mahmood , Md Mahfuzur Rahman , Alex Fedorov , Zening Fu , Sergey Plis

Hyperspectral images (HSIs) have been widely used in a variety of applications thanks to the rich spectral information they are able to provide. Among all HSI processing tasks, HSI denoising is a crucial step. Recently, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2022-02-16 Zhiqiang Wang , Zhenfeng Shao , Xiao Huang , Jiaming Wang , Tao Lu , Sihang Zhang

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Functional alterations in the relevant neural circuits occur from drug addiction over a certain period. And these significant alterations are also revealed by analyzing fMRI. However, because of fMRI's high dimensionality and poor…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Changwei Gong , Changhong Jing , Junren Pan , Shuqiang Wang

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

Identifying epileptic seizures through analysis of the electroencephalography (EEG) signal becomes a standard method for the diagnosis of epilepsy. Manual seizure identification on EEG by trained neurologists is time-consuming,…

Machine Learning · Computer Science 2019-06-07 X. Yao , X. Li , Q. Ye , Y. Huang , Q. Cheng , G. -Q. Zhang

Compressed sensing MRI is a classic inverse problem in the field of computational imaging, accelerating the MR imaging by measuring less k-space data. The deep neural network models provide the stronger representation ability and faster…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Zhiwen Fan , Liyan Sun , Xinghao Ding , Yue Huang , Congbo Cai , John Paisley

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Slow Feature Analysis (SFA) extracts slowly varying features from a quickly varying input signal. It has been successfully applied to modeling the visual receptive fields of the cortical neurons. Sufficient experimental results in…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Zhang Zhang , Dacheng Tao

In recent years, there is strong emphasis on mining medical data using machine learning techniques. A common problem is to obtain a noiseless set of textual documents, with a relevant content for the research question, and developing a…

Machine Learning · Computer Science 2023-10-03 Christian Internò , Eloisa Ambrosini

Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder involving motor neuron degeneration. Significant research has begun to establish brain magnetic resonance imaging (MRI) as a potential biomarker to diagnose and…

Using functional magnetic resonance imaging (fMRI) and deep learning to explore functional brain networks (FBNs) has attracted many researchers. However, most of these studies are still based on the temporal correlation between the sources…

Neurons and Cognition · Quantitative Biology 2022-11-07 Yiheng Liu , Enjie Ge , Ning Qiang , Tianming Liu , Bao Ge

Functional connectivity plays an essential role in modern neuroscience. The modality sheds light on the brain's functional and structural aspects, including mechanisms behind multiple pathologies. One such pathology is schizophrenia which…

Neurons and Cognition · Quantitative Biology 2022-06-07 Maksim Zhdanov , Saskia Steinmann , Nico Hoffmann

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu
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