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Mental disorders are among the leading causes of disability worldwide. The first step in treating these conditions is to obtain an accurate diagnosis, but the absence of established clinical tests makes this task challenging. Machine…

Signal Processing · Electrical Eng. & Systems 2021-10-13 Caroline L. Alves , Aruane M. Pineda , Kirstin Roster , Christiane Thielemann , Francisco A. Rodrigues

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene expression are likely to underpin much of human diversity,…

Genomics · Quantitative Biology 2019-05-31 Akram Yazdani , Raul Mendez Giraldez , Ahmad Samiei

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Channel and spatial attentions have respectively brought significant improvements in extracting feature dependencies and spatial structure relations for various downstream vision tasks. While their combination is more beneficial for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Yunzhong Si , Huiying Xu , Xinzhong Zhu , Wenhao Zhang , Yao Dong , Yuxing Chen , Hongbo Li

Subjective cognitive decline (SCD) is a preclinical stage of Alzheimer's disease (AD) which occurs even before mild cognitive impairment (MCI). Progressive SCD will convert to MCI with the potential of further evolving to AD. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Hao Guan , Ling Yue , Pew-Thian Yap , Shifu Xiao , Andrea Bozoki , Mingxia Liu

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

Statistics Theory · Mathematics 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen

Objective: Multimodal measurements of the same phenomena provide complementary information and highlight different perspectives, albeit each with their own limitations. A focus on a single modality may lead to incorrect inferences, which is…

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Spiking neural networks (SNNs) mimic brain computational strategies, and exhibit substantial capabilities in spatiotemporal information processing. As an essential factor for human perception, visual attention refers to the dynamic process…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Wuque Cai , Hongze Sun , Rui Liu , Yan Cui , Jun Wang , Yang Xia , Dezhong Yao , Daqing Guo

Characterising the heterogeneous presentation of Parkinson's disease (PD) requires integrating biological and clinical markers within a unified predictive framework. While multimodal data provide complementary information, many existing…

Machine Learning · Computer Science 2026-01-05 Dristi Datta , Tanmoy Debnath , Minh Chau , Manoranjan Paul , Gourab Adhikary , Md Geaur Rahman

Deep learning has been recently used for the analysis of neuroimages, such as structural magnetic resonance imaging (MRI), functional MRI, and positron emission tomography (PET), and has achieved significant performance improvements over…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Li Zhang , Mingliang Wang , Mingxia Liu , Daoqiang Zhang

This systematic review assessed the current state and future prospects of artificial intelligence (AI) in schizophrenia rehabilitation management. We reviewed 61 studies on AI-related data types, feature engineering methods, algorithmic…

Artificial Intelligence · Computer Science 2025-01-28 Hongyi Yang , Fangyuan Chang , Dian Zhu , Muroi Fumie , Zhao Liu

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

One notable method for recording brainwaves to identify neurological problems is electroencephalography (hereafter EEG). A trained neuro physician can learn more about how the brain functions through the use of EEGs. However conventionally,…

Neurons and Cognition · Quantitative Biology 2024-02-26 Hari Prasad SV

Recently, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting researchers to have…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Saman Sarraf , Ghassem Tofighi

In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and…

Signal Processing · Electrical Eng. & Systems 2019-06-07 Xinghua Yao , Qiang Cheng , Guo-Qiang Zhang