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Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Mengjiao Hu , Kang Sim , Juan Helen Zhou , Xudong Jiang , Cuntai Guan

The human neocortex is functionally organised at its highest level along a continuous sensory-to-association (AS) hierarchy. This study characterises the AS hierarchy of patients with schizophrenia in a comparison with controls. Using a…

Neurons and Cognition · Quantitative Biology 2025-11-06 Subati Abulikemu , Puria Radmard , Michail Mamalakis , John Suckling

Recently, there has been a growing interest in monitoring brain activity for individual recognition system. So far these works are mainly focussing on single channel data or fragment data collected by some advanced brain monitoring…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Lei Chu , Robert Qiu , Haichun Liu , Zenan Ling , Tianhong Zhang , Jijun Wang

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

Signal Processing · Electrical Eng. & Systems 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Speech-based assessment of the schizophrenia spectrum has been widely researched over in the recent past. In this study, we develop a deep learning framework to estimate schizophrenia severity scores from speech using a feature fusion…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-21 Gowtham Premananth , Carol Espy-Wilson

Schizophrenia (SCZ), as a chronic and persistent disorder, exhibits working memory deficits across various stages of the disorder, yet the neural mechanisms underlying these deficits remain elusive with inconsistent neuroimaging findings.…

Neurons and Cognition · Quantitative Biology 2023-10-16 Yuhao Yao , Shufang Zhang , Boyao Wang , Gaofeng Zhao , Hong Deng , Ying Chen

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic…

Studies on schizophrenia assessments using deep learning typically treat it as a classification task to detect the presence or absence of the disorder, oversimplifying the condition and reducing its clinical applicability. This traditional…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-29 Gowtham Premananth , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Guoxin Wang , Xuyang Cao , Shan An , Fengmei Fan , Chao Zhang , Jinsong Wang , Feng Yu , Zhiren Wang

Structural magnetic resonance imaging (sMRI) is widely used for brain neurological disease diagnosis; while longitudinal MRIs are often collected to monitor and capture disease progression, as clinically used in diagnosing Alzheimer's…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Qiuhui Chen , Yi Hong

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

Neurons and Cognition · Quantitative Biology 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Attention mechanisms, which enable a neural network to accurately focus on all the relevant elements of the input, have become an essential component to improve the performance of deep neural networks. There are mainly two attention…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Qing-Long Zhang Yu-Bin Yang

Visual attention mechanisms have proven to be integrally important constituent components of many modern deep neural architectures. They provide an efficient and effective way to utilize visual information selectively, which has shown to be…

Computer Vision and Pattern Recognition · Computer Science 2019-05-24 Siddhesh Khandelwal , Leonid Sigal

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

This survey presents the most relevant neural network models of autism spectrum disorder and schizophrenia, from the first connectionist models to recent deep network architectures. We analyzed and compared the most representative symptoms…

Neurons and Cognition · Quantitative Biology 2019-11-22 Pablo Lanillos , Daniel Oliva , Anja Philippsen , Yuichi Yamashita , Yukie Nagai , Gordon Cheng