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The detection of new or enlarged white-matter lesions in multiple sclerosis is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not…

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Ashiqur Rahman , Muhammad E. H. Chowdhury , Md Sharjis Ibne Wadud , Rusab Sarmun , Adam Mushtak , Sohaib Bassam Zoghoul , Israa Al-Hashimi

In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek

The black-box nature of deep learning models has raised concerns about their interpretability for successful deployment in real-world clinical applications. To address the concerns, eXplainable Artificial Intelligence (XAI) aims to provide…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Junlin Hou , Jilan Xu , Hao Chen

Skin lesion segmentation can be rather a challenging task owing to the presence of artifacts, low contrast between lesion and boundary, color variegation, fuzzy skin lesion borders and heterogeneous background in dermoscopy images. In this…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 Zanobya N. Khan

Multi-parametric magnetic resonance imaging (mpMRI) has a growing role in detecting prostate cancer lesions. Thus, it is pertinent that medical professionals who interpret these scans reduce the risk of human error by using computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Haoli Yin , Nithin Buduma

Salient instance segmentation is a new challenging task that received widespread attention in the saliency detection area. The new generation of saliency detection provides a strong theoretical and technical basis for video surveillance.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-29 Jialun Pei , He Tang , Tianyang Cheng , Chuanbo Chen

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

In this paper we propose two saliency models for salient object segmentation based on a hierarchical image segmentation, a tree-like structure that represents regions at different scales from the details to the whole image (e.g. gPb-UCM,…

Computer Vision and Pattern Recognition · Computer Science 2015-08-20 Verónica Vilaplana

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Le Feng , Li Xiao

Skin lesion segmentation plays a crucial role in the computer-aided diagnosis of melanoma. Deep Learning models have shown promise in accurately segmenting skin lesions, but their widespread adoption in real-life clinical settings is…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Shankara Narayanan , Sikha OK , Raul Benitez

Semantic mapping based on the supervised object detectors is sensitive to image distribution. In real-world environments, the object detection and segmentation performance can lead to a major drop, preventing the use of semantic mapping in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Chuhao Liu , Ke Wang , Jieqi Shi , Zhijian Qiao , Shaojie Shen

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Computation and Language · Computer Science 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Recently, semi-supervised semantic segmentation has achieved promising performance with a small fraction of labeled data. However, most existing studies treat all unlabeled data equally and barely consider the differences and training…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Zhen Zhao , Sifan Long , Jimin Pi , Jingdong Wang , Luping Zhou

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

This paper is motivated from a fundamental curiosity on what defines a category of object shapes. For example, we may have the common knowledge that a plane has wings, and a chair has legs. Given the large shape variations among different…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Chaozheng Wu , Lin Sun , Xun Xu , Kui Jia

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian