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Magnetic Resonance Imaging (MRI) is an essential diagnostic tool for assessing knee injuries. However, manual interpretation of MRI slices remains time-consuming and prone to inter-observer variability. This study presents a systematic…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Justin Yiu , Kushank Arora , Daniel Steinberg , Rohit Ghiya

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Spatial transcriptomics (ST) technologies enable gene expression profiling with spatial resolution, offering unprecedented insights into tissue organization and disease heterogeneity. However, current analysis methods often struggle with…

In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

A central issue addressed by the rapidly growing research area of eXplainable Artificial Intelligence (XAI) is to provide methods to give explanations for the behaviours of Machine Learning (ML) non-interpretable models after the training.…

Machine Learning · Computer Science 2022-08-24 Andrea Apicella , Salvatore Giugliano , Francesco Isgrò , Roberto Prevete

One principal impediment in the successful deployment of AI-based Computer-Aided Diagnosis (CAD) systems in clinical workflows is their lack of transparent decision making. Although commonly used eXplainable AI methods provide some insight…

Artificial Intelligence · Computer Science 2022-01-05 Adriano Lucieri , Muhammad Naseer Bajwa , Stephan Alexander Braun , Muhammad Imran Malik , Andreas Dengel , Sheraz Ahmed

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Instance-level quantification of kidney functional units is essential for morphometric analysis, yet most publicly available pathology datasets provide only semantic segmentation annotations, where adjacent structures of the same class are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Leiyue Zhao , Tianyu Shi , Daniel Reisenbuchler , Xinzi He , Junchao Zhu , Tianyuan Yao , Yuechen Yang , Yanfan Zhu , Junlin Guo , Gelei Xu , Haichun Yang , Yuankai Huo , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Assessing lesions and tracking their progression over time in brain magnetic resonance (MR) images is essential for diagnosing and monitoring multiple sclerosis (MS). Machine learning models have shown promise in automating the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Berke Doga Basaran , Paul M. Matthews , Wenjia Bai

Visual saliency is a fundamental problem in both cognitive and computational sciences, including computer vision. In this CVPR 2015 paper, we discover that a high-quality visual saliency model can be trained with multiscale features…

Computer Vision and Pattern Recognition · Computer Science 2015-04-13 Guanbin Li , Yizhou Yu

Burn injuries can result from mechanisms such as thermal, chemical, and electrical insults. A prompt and accurate assessment of burns is essential for deciding definitive clinical treatments. Currently, the primary approach for burn…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Mahla Abdolahnejad , Justin Lee , Hannah Chan , Alex Morzycki , Olivier Ethier , Anthea Mo , Peter X. Liu , Joshua N. Wong , Colin Hong , Rakesh Joshi

We examined whether embedding human attention knowledge into saliency-based explainable AI (XAI) methods for computer vision models could enhance their plausibility and faithfulness. We first developed new gradient-based XAI methods for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-08 Guoyang Liu , Jindi Zhang , Antoni B. Chan , Janet H. Hsiao

In recent years, Artificial Intelligence (AI) has proven its relevance for medical decision support. However, the "black-box" nature of successful AI algorithms still holds back their wide-spread deployment. In this paper, we describe an…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Gwenolé Quellec , Hassan Al Hajj , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

We propose a novel segmentation-based explainable artificial intelligence (XAI) method for neural networks working on point cloud classification. As one building block of this method, we propose a novel point-shifting mechanism to introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Raju Ningappa Mulawade , Christoph Garth , Alexander Wiebel

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yasmine Mustafa , Tie Luo

Explainable AI (XAI) for Speech Emotion Recognition (SER) is critical for building transparent, trustworthy models. Current saliency-based methods, adapted from vision, highlight spectrogram regions but fail to show whether these regions…

Machine Learning · Computer Science 2025-11-18 Seham Nasr , Zhao Ren , David Johnson

The semantic segmentation of skin lesions is an important and common initial task in the computer aided diagnosis of dermoscopic images. Although deep learning-based approaches have considerably improved the segmentation accuracy, there is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Kumar Abhishek , Ghassan Hamarneh , Mark S. Drew
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