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Chemical reaction networks (CRNs) are a standard formalism used in chemistry and biology to reason about the dynamics of molecular interaction networks. In their interpretation by ordinary differential equations, CRNs provide a…

Quantitative Methods · Quantitative Biology 2020-07-28 Mathieu Hemery , François Fages , Sylvain Soliman

Realistic human contact networks capable of spreading infectious disease, for example studied in social contact surveys, exhibit both significant degree heterogeneity and clustering, both of which greatly affect epidemic dynamics. To…

Populations and Evolution · Quantitative Biology 2018-10-16 A. Bishop , I. Z. Kiss , T. House

The automated inference of physically interpretable (bio)chemical reaction network models from measured experimental data is a challenging problem whose solution has significant commercial and academic ramifications. It is demonstrated,…

Neural and Evolutionary Computing · Computer Science 2014-12-22 Dominic P. Searson , Mark J. Willis , Allen Wright

Recently there has been growing interest in the use of Maximum Relative Entropy (MaxREnt) as a tool for statistical inference in ecology. In contrast, here we propose MaxREnt as a tool for applying statistical mechanics to ecology. We use…

Populations and Evolution · Quantitative Biology 2007-12-13 Roderick C. Dewar , Annabel Porte

Current interpretability methods focus on explaining a particular model's decision through present input features. Such methods do not inform the user of the sufficient conditions that alter these decisions when they are not desirable.…

Machine Learning · Computer Science 2023-01-20 Julia El Zini , Mohammad Mansour , Mariette Awad

In this paper we study the appearance of bifurcations of limit cycles in an epidemic model with two types of aware individuals. All the transition rates are constant except for the alerting decay rate of the most aware individuals and the…

Populations and Evolution · Quantitative Biology 2023-05-03 David Juher , David Rojas , Joan Saldaña

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

Molecular Networks · Quantitative Biology 2012-04-26 Guy Shinar , Martin Feinberg

This paper considers a deterministic Susceptible-Infected-Susceptible (SIS) networked bivirus epidemic model (termed the bivirus model for short), in which two competing viruses spread through a set of populations (nodes) connected by two…

Dynamical Systems · Mathematics 2024-10-24 Brian D. O. Anderson , Mengbin Ye

Recent work in modeling the coupling between disease dynamics and dynamic social network geometry has led to the examination of how human interactions force a rewiring of connections in a population. Rewiring of the network may be…

Statistical Mechanics · Physics 2009-09-29 Leah B. Shaw , Ira B. Schwartz

The quantitative convergence to equilibrium for reaction-diffusion systems arising from complex balanced chemical reaction networks with mass action kinetics is studied by using the so-called entropy method. In the first part of the paper,…

Analysis of PDEs · Mathematics 2016-11-11 Laurent Desvillettes , Klemens Fellner , Bao Quoc Tang

Hybrid neural network models combine the advantages of a neural network's fitting functionality with differential equation models to reflect actual physical processes and are widely used in analyzing time-series data. Most related studies…

Dynamical Systems · Mathematics 2023-11-10 Chentong Li , Changsheng Zhou , Junmin Liu , Yao Rong

For many physical systems the transition from a stationary solution to sustained small amplitude oscillations corresponds to a Hopf bifurcation. For systems involving impacts, thresholds, switches, or other abrupt events, however, this…

Dynamical Systems · Mathematics 2019-05-07 David J. W. Simpson

Explicit modelling of between-study heterogeneity is essential in network meta-analysis (NMA) to ensure valid inference and avoid overstating precision. While the additive random-effects (RE) model is the conventional approach, the…

Methodology · Statistics 2026-01-21 Xinlei Xu , Caitlin H Daly , Audrey Béliveau

Motivated by investigating multistationarity in biochemical systems, we address saddle-node bifurcations for chemical reaction networks endowed with general kinetics. At positive equilibria, we identify structural network conditions that…

Dynamical Systems · Mathematics 2023-07-24 Nicola Vassena

Discontinuous percolation transitions and the associated tricritical points are manifest in a wide range of both equilibrium and non-equilibrium cooperative phenomena. To demonstrate this, we present and relate the continuous and first…

Disordered Systems and Neural Networks · Physics 2013-05-30 Golnoosh Bizhani , Maya Paczuski , Peter Grassberger

Egocentric-Network Randomized Trials (ENRTs) are increasingly used to estimate causal effects under interference when measuring complete sociocentric network data is infeasible. ENRTs rely on egocentric network sampling, where a set of egos…

Methodology · Statistics 2026-02-06 Bar Weinstein , Daniel Nevo

For the reaction networks with zero-one stoichiometric coefficients (or simply zero-one networks), we prove that if a network admits a Hopf bifurcation, then the rank of the stoichiometric matrix is at least four. As a corollary, we show…

Molecular Networks · Quantitative Biology 2022-08-09 Xiaoxian Tang , Kaizhang Wang

Complex networks describe a wide range of systems in nature and society. Frequently cited examples include Internet, WWW, a network of chemicals linked by chemical reactions, social relationship networks, citation networks, etc. The…

Physics and Society · Physics 2013-02-26 James Kim

Various biological phenomena, like cell differentiation and pattern formation in multicellular organisms, are explained using the bifurcation theory. Molecular network motifs like positive feedback and mutual repressor exhibit bifurcation…

Dynamical Systems · Mathematics 2024-11-26 Shikhar Raj , Biplab Bose

We study a reaction-advection-diffusion model of a target-offender-guardian system designed to capture interactions between urban crime and policing. Using Crandall-Rabinowitz bifurcation theory and spectral analysis, we establish rigorous…

Pattern Formation and Solitons · Physics 2026-04-15 Madi Yerlanov , Qi Wang , Nancy Rodriguez
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