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Prestrained elastic networks arise in a number of biological and technological systems ranging from the cytoskeleton of cells to tensegrity structures. To understand the response of such a network as a function of the prestrain, we consider…

Statistical Mechanics · Physics 2022-07-13 Ihusan Adam , Franco Bagnoli , Duccio Fanelli , L. Mahadevan , Paolo Paoletti

An arc-annotated string is a string of characters, called bases, augmented with a set of pairs, called arcs, each connecting two bases. Given arc-annotated strings $P$ and $Q$ the arc-preserving subsequence problem is to determine if $P$…

Data Structures and Algorithms · Computer Science 2010-09-09 Philip Bille , Inge Li Goertz

We present a numerical study of the ultrametric properties of the set of RNA secondary structures with the maximum number of base pairs (energetically degenerate minima) within the maximum matching model (Nussinov algorithm). Using 18…

Disordered Systems and Neural Networks · Physics 2026-05-27 A. P. Zubarev

In this paper, we extend the notion of gapped strings to elastic-degenerate strings. An elastic-degenerate string can been seen as an ordered collection of k > 1 seeds (substrings/subpatterns) interleaved by elastic-degenerate symbols such…

Data Structures and Algorithms · Computer Science 2016-10-27 Costas Iliopoulos , Ritu Kundu , Solon Pissis

We demonstrate that frequently appearing objects can be discovered by training randomly sampled patches from a small number of images (100 to 200) by self-supervision. Key to this approach is the pattern space, a latent space of patterns…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Hankyu Moon , Heng Hao , Sima Didari , Jae Oh Woo , Patrick Bangert

The contact map of a protein fold is a graph that represents the patterns of contacts in the fold. It is known that the contact map can be decomposed into stacks and queues. RNA secondary structures are special stacks in which the degree of…

Combinatorics · Mathematics 2014-06-05 William Y. C. Chen , Qiang-Hui Guo , Lisa H. Sun , Jian Wang

RNA design shows growing applications in synthetic biology and therapeutics, driven by the crucial role of RNA in various biological processes. A fundamental challenge is to find functional RNA sequences that satisfy given structural…

Biomolecules · Quantitative Biology 2024-04-18 Han Huang , Ziqian Lin , Dongchen He , Liang Hong , Yu Li

Dual graphs have been applied to model RNA secondary structures with pseudoknots, or intertwined base pairs. In previous works, a linear-time algorithm was introduced to partition dual graphs into maximally connected components called…

Biomolecules · Quantitative Biology 2021-09-09 Louis Petingi

We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures. Our approach is based on tree decomposition of…

Quantitative Methods · Quantitative Biology 2012-06-21 Philippe Rinaudo , Yann Ponty , Dominique Barth , Alain Denise

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

All known terrestrial proteins are coded as continuous strings of ~20 amino acids. The patterns formed by the repetitions of elements in groups of finite sequences describes the natural architectures of protein families. We present a method…

Biomolecules · Quantitative Biology 2018-07-30 Pablo Turjanski , Diego U. Ferreiro

The measurement of the similarity of RNA secondary structures, and in general of contact structures, of a fixed length has several specific applications. For instance, it is used in the analysis of the ensemble of suboptimal secondary…

Discrete Mathematics · Computer Science 2007-05-23 Mercé Llabrés , Francesc Rosselló

The amount of information propagated by an intermediate heavy particle exhibits characteristic features in inelastic scatterings with $n\geq 3$ final particles. As the total energy increases, the entanglement entropy, between its decay…

High Energy Physics - Theory · Physics 2025-10-03 Chon Man Sou , Yi Wang , Xingkai Zhang

Because of the double-helical structure of DNA, in which two strands of complementary nucleotides intertwine around each other, a covalently closed DNA molecule with no interruptions in either strand can be viewed as two interlocked…

Biomolecules · Quantitative Biology 2015-05-13 Lauren A. Britton , Wilma K. Olson , Irwin Tobias

An arrangement of pseudocircles is a finite set of oriented closed Jordan curves each two of which cross each other in exactly two points. To describe the combinatorial structure of arrangements on closed orientable surfaces, in (Linhart,…

Combinatorics · Mathematics 2007-05-23 Ronald Ortner

Nucleic acids are highly deformable helical molecules constantly stretched, twisted and bent in their biological functioning. Single molecule experiments have shown that double stranded (ds)-RNA and standard ds-DNA have opposite…

Soft Condensed Matter · Physics 2023-06-28 Marco Zoli

Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tests have shown that selective 2'-hydroxyl acylation by primer…

Quantitative Methods · Quantitative Biology 2011-09-08 Wipapat Kladwang , Christopher C. VanLang , Pablo Cordero , Rhiju Das

Ribonucleic Acid (RNA) can fold into shapes that perform functions in the cell. These foldings are governed by Watson-Crick base pairing, namely Adenine to Uracil and Cytosine to Guanine (A-U and G-C). The properties of the H-P…

Combinatorics · Mathematics 2018-12-18 Ben Y. Maron

Finding patterns in graphs is a fundamental problem in databases and data mining. In many applications, graphs are temporal and evolve over time, so we are interested in finding durable patterns, such as triangles and paths, which persist…

Databases · Computer Science 2024-03-26 Pankaj K. Agarwal , Xiao Hu , Stavros Sintos , Jun Yang

We study theoretically the denaturation of single RNA molecules by mechanical stretching, focusing on signatures of the (un)folding pathway in molecular fluctuations. Our model describes the interactions between nucleotides by incorporating…

Soft Condensed Matter · Physics 2009-11-07 Ulrich Gerland , Ralf Bundschuh , Terence Hwa
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