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This paper studies unsupervised/self-supervised whole-graph representation learning, which is critical in many tasks such as molecule properties prediction in drug and material discovery. Existing methods mainly focus on preserving the…

Machine Learning · Computer Science 2021-06-09 Minghao Xu , Hang Wang , Bingbing Ni , Hongyu Guo , Jian Tang

Capsule networks aim to parse images into a hierarchy of objects, parts and relations. While promising, they remain limited by an inability to learn effective low level part descriptions. To address this issue we propose a way to learn…

Computer Vision and Pattern Recognition · Computer Science 2021-02-22 Sara Sabour , Andrea Tagliasacchi , Soroosh Yazdani , Geoffrey E. Hinton , David J. Fleet

Improved understanding of charge-transport in single molecules is essential for harnessing the potential of molecules e.g. as circuit components at the ultimate size limit. However, interpretation and analysis of the large, stochastic…

Mesoscale and Nanoscale Physics · Physics 2020-08-06 Nathan D. Bamberger , Jeffrey A. Ivie , Keshaba N. Parida , Dominic V. McGrath , Oliver L. A. Monti

Modeling the relationship between chemical structure and molecular activity is a key goal in drug development. Many benchmark tasks have been proposed for molecular property prediction, but these tasks are generally aimed at specific,…

Quantitative Methods · Quantitative Biology 2020-10-05 Samuel G. Finlayson , Matthew B. A. McDermott , Alex V. Pickering , Scott L. Lipnick , Isaac S. Kohane

A proof-of-concept framework for identifying molecules of unknown elemental composition and structure using experimental rotational data and probabilistic deep learning is presented. Using a minimal set of input data determined…

Chemical Physics · Physics 2020-07-01 Michael C. McCarthy , Kin Long Kelvin Lee

The local arrangement of atoms is one of the most important predictors of mechanical and functional properties of materials. However, algorithms for identifying the geometrical arrangements of atoms in complex materials systems are lacking.…

Materials Science · Physics 2019-04-15 Arash Dehghan Banadaki , Jason J. Maldonis , Paul M. Voyles , Srikanth Patala

With the invention of scanning probe techniques, direct imaging of single atoms and molecules became possible. Today, scanning tunnelling microscopy (STM) routinely provides angstrom-scale image resolution. At the same time, however, STM…

Mesoscale and Nanoscale Physics · Physics 2024-01-30 C. Weiss , C. Wagner , C. Kleimann , F. S. Tautz , R. Temirov

The short and intense pulses of the new X-ray free electron lasers, now operational or under construction, may make possible diffraction experiments on single molecule-sized objects with high resolution, before radiation damage destroys the…

Data Analysis, Statistics and Probability · Physics 2012-04-11 Miklós Tegze , Gábor Bortel

Quantitative analysis of microstructural features on the nanoscale, including precipitates, local chemical orderings (LCOs) or structural defects (e.g. stacking faults) plays a pivotal role in understanding the mechanical and physical…

Recent advances in scanning transmission electron and scanning tunneling microscopies allow researchers to measure materials structural and electronic properties, such as atomic displacements and charge density modulations, at an Angstrom…

Recording atomic-resolution transmission electron microscopy (TEM) images is becoming increasingly routine. A new bottleneck is then analyzing this information, which often involves time-consuming manual structural identification. We have…

Modern computational organic chemistry is becoming increasingly data-driven. There remain a large number of important unsolved problems in this area such as product prediction given reactants, drug discovery, and metric-optimized molecule…

Biomolecules · Quantitative Biology 2026-02-10 Josh Payne , Mario Srouji , Dian Ang Yap , Vineet Kosaraju

Identifying local structural motifs and packing patterns of molecular solids is a challenging task for both simulation and experiment. We demonstrate two novel approaches to characterize local environments in different polymorphs of…

Materials Science · Physics 2024-04-02 Daisuke Kuroshima , Michael Kilgour , Mark E. Tuckerman , Jutta Rogal

Modern research increasingly relies on automated methods to assist researchers. An example of this is Optical Chemical Structure Recognition (OCSR), which aids chemists in retrieving information about chemicals from large amounts of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Thomas Jurriaans , Kinga Szarkowska , Eric Nalisnick , Markus Schwoerer , Camilo Thorne , Saber Akhondi

Online structure learning approaches, such as those stemming from Statistical Relational Learning, enable the discovery of complex relations in noisy data streams. However, these methods assume the existence of fully-labelled training data,…

Artificial Intelligence · Computer Science 2019-02-21 Evangelos Michelioudakis , Alexander Artikis , Georgios Paliouras

I present a strategy for unsupervised manifold learning on local atomic environments in molecular simulations based on simple rotation- and permutation-invariant three-body features. These features are highly descriptive, generalize to…

Materials Science · Physics 2023-01-03 Wesley F. Reinhart

Tables are information-rich structured objects in document images. While significant work has been done in localizing tables as graphic objects in document images, only limited attempts exist on table structure recognition. Most existing…

Computer Vision and Pattern Recognition · Computer Science 2020-10-12 Sachin Raja , Ajoy Mondal , C. V. Jawahar

Nuclear magnetic resonance (NMR) spectroscopy provides an experimental readout of local chemical environments, but its use in molecular representation learning has been constrained by heterogeneous data and incomplete atom-level…

Chemical Physics · Physics 2026-05-12 Jiebin Fang , Zidi Yan , Churu Mao , Yongjun Jiang , Xinyi Tang , Lei Miao , Dan Lu , Yun Huang , Wanjing Ding , Zhongjun Ma

Machine-learning models in chemistry - when based on descriptors of atoms embedded within molecules - face essential challenges in transferring the quality of predictions of local electronic structures and their associated properties across…

Chemical Physics · Physics 2024-09-27 Frederik Ø. Kjeldal , Janus J. Eriksen

Spectroscopic techniques are essential tools for determining the structure of molecules. Different spectroscopic techniques, such as Nuclear magnetic resonance (NMR), Infrared spectroscopy, and Mass Spectrometry, provide insight into the…

Chemical Physics · Physics 2024-10-30 Marvin Alberts , Oliver Schilter , Federico Zipoli , Nina Hartrampf , Teodoro Laino
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