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Hyperbolic geometry has been successfully applied in modeling brain cortical and subcortical surfaces with general topological structures. However such approaches, similar to other surface based brain morphology analysis methods, usually…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 J. Zhang , Q. Dong , J. Shi , Q. Li , C. M. Stonnington , B. A. Gutman , K. Chen , E. M. Reiman , R. J. Caselli , P. M. Thompson , J. Ye , Y. Wang

Most cloud services and distributed applications rely on hashing algorithms that allow dynamic scaling of a robust and efficient hash table. Examples include AWS, Google Cloud and BitTorrent. Consistent and rendezvous hashing are algorithms…

Data Structures and Algorithms · Computer Science 2022-05-17 Mike Heddes , Igor Nunes , Tony Givargis , Alexandru Nicolau , Alex Veidenbaum

This study introduces a pioneering Dynamic Hypergraph Networks (DHCE) model designed to predict future medical diagnoses from electronic health records with enhanced accuracy. The DHCE model innovates by identifying and differentiating…

Machine Learning · Computer Science 2025-01-07 Wangying Yang , Zitao Zheng , Zhizhong Wu , Bo Zhang , Yuanfang Yang

Feature selection techniques are essential for high-dimensional data analysis. In the last two decades, their popularity has been fuelled by the increasing availability of high-throughput biomolecular data where high-dimensionality is a…

Quantitative Methods · Quantitative Biology 2024-01-18 Pengyi Yang , Hao Huang , Chunlei Liu

Mass spectrometry-based proteomics is a key enabler for personalized healthcare, providing a deep dive into the complex protein compositions of biological systems. This technology has vast applications in biotechnology and biomedicine but…

Quantitative Methods · Quantitative Biology 2023-11-23 Sumukh Pinge , Weihong Xu , Jaeyoung Kang , Tianqi Zhang , Neima Moshiri , Wout Bittremieux , Tajana Rosing

In an effort to overcome the data deluge in computational biology and bioinformatics and to facilitate bioinformatics research in the era of big data, we identify some of the most influential algorithms that have been widely used in the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-03 Faraz Faghri , Sayed Hadi Hashemi , Mohammad Babaeizadeh , Mike A. Nalls , Saurabh Sinha , Roy H. Campbell

Hyperdimensional computing (HDC) is a biologically-inspired framework which represents symbols with high-dimensional vectors, and uses vector operations to manipulate them. The ensemble of a particular vector space and a prescribed set of…

Machine Learning · Computer Science 2023-02-16 Kenneth L. Clarkson , Shashanka Ubaru , Elizabeth Yang

We introduce Residue Hyperdimensional Computing, a computing framework that unifies residue number systems with an algebra defined over random, high-dimensional vectors. We show how residue numbers can be represented as high-dimensional…

Neural and Evolutionary Computing · Computer Science 2023-11-09 Christopher J. Kymn , Denis Kleyko , E. Paxon Frady , Connor Bybee , Pentti Kanerva , Friedrich T. Sommer , Bruno A. Olshausen

To better understand DNA's 3D folding in cell nuclei, researchers developed chromosome capture methods such as Hi-C that measure the contact frequencies between all DNA segment pairs across the genome. As Hi-C data sets often are massive,…

Biological Physics · Physics 2023-11-14 Anton Holmgren , Dolores Bernenko , Ludvig Lizana

Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon…

Biomolecules · Quantitative Biology 2023-12-05 Gregory W. Kyro , Rafael I. Brent , Victor S. Batista

We report recent research on computing with biology-based neural network models by means of physics-based opto-electronic hardware. New technology provides opportunities for very-high-speed computation and uncovers problems obstructing the…

Neural and Evolutionary Computing · Computer Science 2010-06-09 A. Steven Younger , Emmett Redd

The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…

Machine Learning · Computer Science 2025-10-28 Rekha R Nair , Tina Babu , Alavikunhu Panthakkan , Hussain Al-Ahmad , Balamurugan Balusamy

Hyperdimensional Computing (HDC), also known as Vector-Symbolic Architectures (VSA), is a promising framework for the development of cognitive architectures and artificial intelligence systems, as well as for technical applications and…

Artificial Intelligence · Computer Science 2022-01-03 Dmitri A. Rachkovskij

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Machine learning based on neural networks has advanced rapidly, but the high energy consumption required for training and inference remains a major challenge. Hyperdimensional Computing (HDC) offers a lightweight, brain-inspired alternative…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-10 Wakuto Matsumi , Riaz-Ul-Haque Mian

The proliferation of Internet-of-Things (IoT) devices has led to an unprecedented volume of multivariate time series (MTS) data, requiring efficient and accurate processing for timely decision-making in resource-constrained edge…

Machine Learning · Computer Science 2025-09-30 Jingtao Zhang , Yi Liu , Qi Shen , Changhong Wang

This paper discusses the meaning and scope of biological hypercomputation (BH). The framework here is computational, and from the outset it should be clear that life is not a standard Turing Machine. Living systems hypercompute, but the…

Adaptation and Self-Organizing Systems · Physics 2012-10-18 Carlos Eduardo Maldonado , Nelson Alfonso Gomez-Cruz

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

Neural network models can now recognise images, understand text, translate languages, and play many human games at human or superhuman levels. These systems are highly abstracted, but are inspired by biological brains and use only…

Neurons and Cognition · Quantitative Biology 2019-03-06 Katherine R. Storrs , Nikolaus Kriegeskorte

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri