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Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this…

Neurons and Cognition · Quantitative Biology 2018-11-01 David G. T. Barrett , Ari S. Morcos , Jakob H. Macke

We propose a novel randomized algorithm for constructing binary neural networks with tunable accuracy. This approach is motivated by hyperdimensional computing (HDC), which is a brain-inspired paradigm that leverages high-dimensional vector…

Machine Learning · Computer Science 2025-11-27 Alireza Aghasi , Nicholas Marshall , Saeid Pourmand , Wyatt Whiting

In the past several years, we have taken advantage of a number of opportunities to advance the intersection of next generation high-performance computing AI and big data technologies through partnerships in precision medicine. Today we are…

Artificial Intelligence · Computer Science 2018-05-11 Edmon Begoli , Jim Brase , Bambi DeLaRosa , Penelope Jones , Dimitri Kusnezov , Jason Paragas , Rick Stevens , Fred Streitz , Georgia Tourassi

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

High-dimensional data and high-dimensional representations of reality are inherent features of modern Artificial Intelligence systems and applications of machine learning. The well-known phenomenon of the "curse of dimensionality" states:…

Machine Learning · Computer Science 2020-01-22 Alexander N. Gorban , Valery A. Makarov , Ivan Y. Tyukin

In this paper, we present a significant improvement of Quick Hypervolume algorithm, one of the state-of-the-art algorithms for calculating exact hypervolume of the space dominated by a set of d-dimensional points. This value is often used…

Neural and Evolutionary Computing · Computer Science 2017-08-14 Andrzej Jaszkiewicz

Superconducting materials find applications in a rapidly growing number of technological areas, and searching for novel superconductors continues to be a major scientific task. However, the steady increase in the complexity of candidate…

Superconductivity · Physics 2019-12-20 J. Yuan , V. Stanev , C. Gao , I. Takeuchi , K. Jin

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Deep learning techniques have driven significant progress in various analytical tasks within 3D genomics in computational biology. However, a holistic understanding of 3D genomics knowledge remains underexplored. Here, we propose MIX-HIC,…

Machine Learning · Computer Science 2025-10-29 Minghao Yang , Pengteng Li , Yan Liang , Qianyi Cai , Zhihang Zheng , Shichen Zhang , Pengfei Zhang , Zhi-An Huang , Hui Xiong

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

In several application domains, high-dimensional observations are collected and then analysed in search for naturally occurring data clusters which might provide further insights about the nature of the problem. In this paper we describe a…

Machine Learning · Statistics 2012-03-07 Brian McWilliams , Giovanni Montana

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

Hyperspectral imaging provides detailed information about the scanned objects, as it captures their spectral characteristics within a large number of wavelength bands. Classification of such data has become an active research topic due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jakub Nalepa , Lukasz Tulczyjew , Michal Myller , Michal Kawulok

The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive…

Emerging Technologies · Computer Science 2025-11-04 Yannic Talavera , Bernd Ulmann

Robust generalization beyond training distributions remains a critical challenge for deep neural networks. This is especially pronounced in medical image analysis, where data is often scarce and covariate shifts arise from different…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Francesco Di Salvo , Sebastian Doerrich , Jonas Alle , Christian Ledig

In medical imaging analysis, deep learning has shown promising results. We frequently rely on volumetric data to segment medical images, necessitating the use of 3D architectures, which are commended for their capacity to capture interslice…

Image and Video Processing · Electrical Eng. & Systems 2023-05-18 Ikboljon Sobirov , Numan Saeed , Mohammad Yaqub

Despite their potential to address crucial bottlenecks in computing architectures and contribute to the pool of biological inspiration for engineering, pathological biological mechanisms remain absent from computational theory. We hereby…

Neural and Evolutionary Computing · Computer Science 2025-03-18 Rosalia Moreddu , Michael Levin

The advent of modern technology, permitting the measurement of thousands of characteristics simultaneously, has given rise to floods of data characterized by many large or even huge datasets. This new paradigm presents extraordinary…

Methodology · Statistics 2019-02-14 A. M. Pires , J. A. Branco

Case-based Reasoning (CBR) on high-dimensional and heterogeneous data is a trending yet challenging and computationally expensive task in the real world. A promising approach is to obtain low-dimensional hash codes representing cases and…

Information Retrieval · Computer Science 2022-06-30 Qi Zhang , Liang Hu , Chongyang Shi , Ke Liu , Longbing Cao

As data structures and mathematical objects used for complex systems modeling, hypergraphs sit nicely poised between on the one hand the world of network models, and on the other that of higher-order mathematical abstractions from algebra,…