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The applications of traditional statistical feature selection methods to high-dimension, low sample-size data often struggle and encounter challenging problems, such as overfitting, curse of dimensionality, computational infeasibility, and…

Machine Learning · Statistics 2023-12-19 Kexuan Li , Fangfang Wang , Lingli Yang , Ruiqi Liu

High-dimensional distributed semantic spaces have proven useful and effective for aggregating and processing visual, auditory, and lexical information for many tasks related to human-generated data. Human language makes use of a large and…

Computation and Language · Computer Science 2021-04-02 Jussi Karlgren , Pentti Kanerva

Deep neural networks have proven to be very effective for computer vision tasks, such as image classification, object detection, and semantic segmentation -- these are primarily applied to color imagery and video. In recent years, there has…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Xiong Zhou , Saurabh Prasad

The implementation of Hyperdimensional Computing (HDC) on In-Memory Computing (IMC) architectures faces significant challenges due to the mismatch between highdimensional vectors and IMC array sizes, leading to inefficient memory…

Hardware Architecture · Computer Science 2025-02-13 Do Yeong Kang , Yeong Hwan Oh , Chanwook Hwang , Jinhee Kim , Kang Eun Jeon , Jong Hwan Ko

We construct a two-layered model for learning and generating sequential data that is both computationally fast and competitive with vanilla Tsetlin machines, adding numerous advantages. Through the use of hyperdimensional vector computing…

Machine Learning · Computer Science 2024-08-30 Christian D. Blakely

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Hyperbolic graph convolutional networks (HGCNs) have demonstrated significant potential in extracting information from hierarchical graphs. However, existing HGCNs are limited to shallow architectures due to the computational expense of…

Machine Learning · Computer Science 2024-08-12 Jiaxu Liu , Xinping Yi , Xiaowei Huang

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

Computational methods that operate on three-dimensional molecular structure have the potential to solve important questions in biology and chemistry. In particular, deep neural networks have gained significant attention, but their…

Abstract. The advancement of deep learning has coincided with the proliferation of both models and available data. The surge in dataset sizes and the subsequent surge in computational requirements have led to the development of the Dataset…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Jun-Yeong Moon , Jung Uk Kim , Gyeong-Moon Park

Recent advances in spatial omics technologies have revolutionized our ability to study biological systems with unprecedented resolution. By preserving the spatial context of molecular measurements, these methods enable comprehensive mapping…

Quantitative Methods · Quantitative Biology 2025-09-18 Zhiwei Fan , Tiangang Wang , Kexin Huang , Binwu Ying , Xiaobo Zhou

Sampling-based inference has seen a surge of interest in recent years. Hamiltonian Monte Carlo (HMC) has emerged as a powerful algorithm that leverages concepts from Hamiltonian dynamics to efficiently explore complex target distributions.…

Computation · Statistics 2026-04-07 Arghya Mukherjee , Dootika Vats

Hyperdimensional Computing (HDC) is a computationally and data-efficient paradigm that acts as a bridge between connectionist and symbolic approaches to artificial intelligence (AI). However, HDC's simplicity poses challenges for encoding…

Machine Learning · Computer Science 2026-05-28 Calvin Yeung , Zhuowen Zou , SungHeon Jeong , Wenjun Huang , Nathaniel D Bastian , Mohsen Imani

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

The explosion of data throughout the biomedical sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression, but harnessing these large and diverse datasets remains challenging. Here, we…

Quantitative Methods · Quantitative Biology 2019-12-03 Sam F. Greenbury , Mauricio Barahona , Iain G. Johnston

Recent years witnessed remarkable progress in computational histopathology, largely fueled by deep learning. This brought the clinical adoption of deep learning-based tools within reach, promising significant benefits to healthcare,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-29 Ahmad Obeid , Said Boumaraf , Anabia Sohail , Taimur Hassan , Sajid Javed , Jorge Dias , Mohammed Bennamoun , Naoufel Werghi

Geometric Deep Learning techniques have become a transformative force in the field of Computer-Aided Design (CAD), and have the potential to revolutionize how designers and engineers approach and enhance the design process. By harnessing…

Computational Geometry · Computer Science 2025-07-08 Negar Heidari , Alexandros Iosifidis

Many problems in science and engineering can be formulated in terms of geometric patterns in high-dimensional spaces. We present high-dimensional convolutional networks (ConvNets) for pattern recognition problems that arise in the context…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Christopher Choy , Junha Lee , Rene Ranftl , Jaesik Park , Vladlen Koltun

Feature selection is a critical step in the analysis of high-dimensional data, where the number of features often vastly exceeds the number of samples. Effective feature selection not only improves model performance and interpretability but…

Machine Learning · Computer Science 2025-01-27 Raquel Espinosa , Gracia Sánchez , José Palma , Fernando Jiménez

Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Kamyar Barakati , Yu Liu , Utkarsh Pratiush , Boris N. Slautin , Sergei V. Kalinin
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