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Machine learning methods are used to discover complex nonlinear relationships in biological and medical data. However, sophisticated learning models are computationally unfeasible for data with millions of features. Here we introduce the…

Brain-inspired hyperdimensional computing (HDC) is continuously gaining remarkable attention. It is a promising alternative to traditional machine-learning approaches due to its ability to learn from little data, lightweight implementation,…

Emerging Technologies · Computer Science 2023-04-27 Simon Thomann , Paul R. Genssler , Hussam Amrouch

Deep convolutional neural networks (DCNNs) have become the state-of-the-art computational models of biological object recognition. Their remarkable success has helped vision science break new ground and recent efforts have started to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Leonard E. van Dyck , Walter R. Gruber

One of the fundamental problems in machine learning is the estimation of a probability distribution from data. Many techniques have been proposed to study the structure of data, most often building around the assumption that observations…

Machine Learning · Statistics 2013-02-22 Oren Rippel , Ryan Prescott Adams

The convolution operation is a central building block of neural network architectures widely used in computer vision. The size of the convolution kernels determines both the expressiveness of convolutional neural networks (CNN), as well as…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tianyu Ma , Adrian V. Dalca , Mert R. Sabuncu

We present a novel way to encode compositional information in high-dimensional (HD) vectors. Inspired by chromosomal crossover, random HD vectors are recursively interwoven, with a fraction of one vector's components masked out and replaced…

Neurons and Cognition · Quantitative Biology 2019-11-18 Rich Pang

Genomic sequence analysis plays a crucial role in various scientific and medical domains. Traditional machine-learning approaches often struggle to capture the complex relationships and hierarchical structures of sequence data when working…

Machine Learning · Computer Science 2025-10-02 Sarwan Ali , Haris Mansoor , Murray Patterson

Hyperdimensional computing (HDC) is an emerging computing paradigm that represents, manipulates, and communicates data using long random vectors known as hypervectors. Among different hardware platforms capable of executing HDC algorithms,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-15 Robert Guirado , Abbas Rahimi , Geethan Karunaratne , Eduard Alarcón , Abu Sebastian , Sergi Abadal

Neuro-symbolic artificial intelligence (neuro-symbolic AI) excels in logical analysis and reasoning. Hyperdimensional Computing (HDC), a promising brain-inspired computational model, is integral to neuro-symbolic AI. Various HDC models have…

Symbolic Computation · Computer Science 2025-07-17 Yifei Zhou , Xuchu Huang , Chenyu Ni , Min Zhou , Zheyu Yan , Xunzhao Yin , Cheng Zhuo

Novel technologies and new materials are in high demand for future energy-efficient electronic devices to overcome the fundamental limitations of miniaturization of current silicon-based devices. Two-dimensional (2D) materials show…

Computational Physics · Physics 2021-12-20 Lei Shen , Jun Zhou , Tong Yang , Ming Yang , Yuan Ping Feng

Clustering analysis is of substantial significance for data mining. The properties of big data raise higher demand for more efficient and economical distributed clustering methods. However, existing distributed clustering methods mainly…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-03 Yifeng Xiao , Jiang Xue , Deyu Meng

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

We model human and animal learning by computing with high-dimensional vectors (H = 10,000 for example). The architecture resembles traditional (von Neumann) computing with numbers, but the instructions refer to vectors and operate on them…

Machine Learning · Computer Science 2026-02-24 Pentti Kanerva

Hyperbox-based classification has been seen as a promising technique in which decisions on the data are represented as a series of orthogonal, multidimensional boxes (i.e., hyperboxes) that are often interpretable and human-readable.…

Machine Learning · Computer Science 2023-08-02 Denis Mayr Lima Martins , Christian Lülf , Fabian Gieseke

In the supervised learning domain, considering the recent prevalence of algorithms with high computational cost, the attention is steering towards simpler, lighter, and less computationally extensive training and inference approaches. In…

Machine Learning · Computer Science 2022-09-02 Antonello Rosato , Massimo Panella , Denis Kleyko

This is Part II of the two-part comprehensive survey devoted to a computing framework most commonly known under the names Hyperdimensional Computing and Vector Symbolic Architectures (HDC/VSA). Both names refer to a family of computational…

Artificial Intelligence · Computer Science 2023-08-02 Denis Kleyko , Dmitri A. Rachkovskij , Evgeny Osipov , Abbas Rahimi

Hyperdimensional computing (HDC) is a promising approach for energy-efficient edge machine learning (ML), where low latency, low power, and tight memory budgets are essential. However, traditional HDC relies on symbolic binding and…

Hardware Architecture · Computer Science 2026-05-26 Sabrina Hassan Moon , Abu Kaisar Mohammad Masum , Sercan Aygun , Dayane Reis

Brain Computer Interface (BCI) technologies have the potential to improve the lives of millions of people around the world, whether through assistive technologies or clinical diagnostic tools. Despite advancements in the field, however, at…

Machine Learning · Computer Science 2023-01-31 Chad Mello , Troy Weingart , Ethan M. Rudd

Deep Learning is mostly responsible for the surge of interest in Artificial Intelligence in the last decade. So far, deep learning researchers have been particularly successful in the domain of image processing, where Convolutional Neural…

Machine Learning · Computer Science 2023-08-31 Andrii Skliar , Maurice Weiler

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen
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