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Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jiaqi Shang , Haojin Wu , Yinyi Lai , Zongyu Li , Chenghao Zhang , Jia Guo

Image synthesis is used to generate synthetic CTs (sCTs) from on-treatment cone-beam CTs (CBCTs) with a view to improving image quality and enabling accurate dose computation to facilitate a CBCT-based adaptive radiotherapy workflow. As…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Chelsea A. H. Sargeant , Edward G. A. Henderson , Dónal M. McSweeney , Aaron G. Rankin , Denis Page

Multi-phase CT is widely adopted for the diagnosis of kidney cancer due to the complementary information among phases. However, the complete set of multi-phase CT is often not available in practical clinical applications. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Kwang-Hyun Uhm , Seung-Won Jung , Moon Hyung Choi , Sung-Hoo Hong , Sung-Jea Ko

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients. This paper describes a development in improving the learning-based registration algorithms, for this challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Ziyi Shen , Qianye Yang , Yuming Shen , Francesco Giganti , Vasilis Stavrinides , Richard Fan , Caroline Moore , Mirabela Rusu , Geoffrey Sonn , Philip Torr , Dean Barratt , Yipeng Hu

Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Junyu Chen , Ye Li , Yong Du , Eric C. Frey

Cone-Beam Computed Tomography (CBCT) is widely used for real-time intraoperative imaging due to its low radiation dose and high acquisition speed. However, despite its high resolution, CBCT suffers from significant artifacts and thereby…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Maximilian Tschuchnig , Lukas Lamminger , Philipp Steininger , Michael Gadermayr

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Lin Tian , Connor Puett , Peirong Liu , Zhengyang Shen , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

In this paper, we propose a novel 3D registration paradigm, Generative Point Cloud Registration, which bridges advanced 2D generative models with 3D matching tasks to enhance registration performance. Our key idea is to generate cross-view…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Haobo Jiang , Jin Xie , Jian Yang , Liang Yu , Jianmin Zheng

In the field of radiotherapy, accurate imaging and image registration are of utmost importance for precise treatment planning. Magnetic Resonance Imaging (MRI) offers detailed imaging without being invasive and excels in soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Saba Nikbakhsh , Lachin Naghashyar , Morteza Valizadeh , Mehdi Chehel Amirani

In this work, we present a method for synthetic CT (sCT) generation from zero-echo-time (ZTE) MRI aimed at structural and quantitative accuracies of the image, with a particular focus on the accurate bone density value prediction. We…

Electron density maps must be accurately estimated to achieve valid dose calculation in MR-only radiotherapy. The goal of this study is to assess whether two deep learning models, the conditional generative adversarial network (cGAN) and…

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

Graph neural networks (GNNs) have been proposed for medical image segmentation, by predicting anatomical structures represented by graphs of vertices and edges. One such type of graph is predefined with fixed size and connectivity to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Qian Li , Yunguan Fu , Qianye Yang , Zhijiang Du , Hongjian Yu , Yipeng Hu

Purpose: To assess the feasibility of deep learning-based high resolution synthetic CT generation from MRI scans of the lower arm for orthopedic applications. Methods: A conditional Generative Adversarial Network was trained to synthesize…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Frank Zijlstra , Koen Willemsen , Mateusz C. Florkow , Ralph J. B. Sakkers , Harrie H. Weinans , Bart C. H. van der Wal , Marijn van Stralen , Peter R. Seevinck

Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Ruiwen Xing , Thomas Humphries , Dong Si

Medical image translation has the potential to reduce the imaging workload, by removing the need to capture some sequences, and to reduce the annotation burden for developing machine learning methods. GANs have been used successfully to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Pauliina Paavilainen , Saad Ullah Akram , Juho Kannala
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