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Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Automated medical image segmentation is becoming increasingly crucial to modern clinical practice, driven by the growing demand for precise diagnosis, the push towards personalized treatment plans, and the advancements in machine learning…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Tan-Hanh Pham , Xianqi Li , Kim-Doang Nguyen

Medical image synthesis is a challenging task due to the scarcity of paired data. Several methods have applied CycleGAN to leverage unpaired data, but they often generate inaccurate mappings that shift the anatomy. This problem is further…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Minh Hieu Phan , Zhibin Liao , Johan W. Verjans , Minh-Son To

Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Weijian Huang , Hao Yang , Xinfeng Liu , Cheng Li , Ian Zhang , Rongpin Wang , Hairong Zheng , Shanshan Wang

Multimodal image registration between diffusion MRI (dMRI) and T1-weighted (T1w) MRI images is a critical step for aligning diffusion-weighted imaging (DWI) data with structural anatomical space. Traditional registration methods often…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Xiaofan Wang , Junyi Wang , Yuqian Chen , Lauren J. O' Donnell , Fan Zhang

Person image generation aims to perform non-rigid deformation on source images, which generally requires unaligned data pairs for training. Recently, self-supervised methods express great prospects in this task by merging the disentangled…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Zijian Wang , Xingqun Qi , Kun Yuan , Muyi Sun

In recent advancements in proton therapy, MR-based treatment planning is gaining momentum to minimize additional radiation exposure compared to traditional CT-based methods. This transition highlights the critical need for accurate MR-to-CT…

Medical Physics · Physics 2024-07-02 Muheng Li , Xia Li , Sairos Safai , Damien Weber , Antony Lomax , Ye Zhang

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

In radiotherapy planning, manual contouring is labor-intensive and time-consuming. Accurate and robust automated segmentation models improve the efficiency and treatment outcome. We aim to develop a novel hybrid deep learning approach,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhuangzhuang Zhang , Tianyu Zhao , Hiram Gay , Weixiong Zhang , Baozhou Sun

Purpose: Automated distinct bone segmentation from CT scans is widely used in planning and navigation workflows. U-Net variants are known to provide excellent results in supervised semantic segmentation. However, in distinct bone…

Image and Video Processing · Electrical Eng. & Systems 2023-02-01 Eva Schnider , Julia Wolleb , Antal Huck , Mireille Toranelli , Georg Rauter , Magdalena Müller-Gerbl , Philippe C. Cattin

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Due to a high heterogeneity in pose and size and to a limited number of available data, segmentation of pediatric images is challenging for deep learning methods. In this work, we propose a new CNN architecture that is pose and scale…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Giammarco La Barbera , Pietro Gori , Haithem Boussaid , Bruno Belucci , Alessandro Delmonte , Jeanne Goulin , Sabine Sarnacki , Laurence Rouet , Isabelle Bloch

Introduction: This study uses KV CBCT based Synthetic CT (sCT) generated through Velocity workstation and compare the target and normal tissue doses with Adaptive plan CT doses. Methods: Thirty head and neck cancer patients undergoing…

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Chenyu You , Guang Li , Yi Zhang , Xiaoliu Zhang , Hongming Shan , Shenghong Ju , Zhen Zhao , Zhuiyang Zhang , Wenxiang Cong , Michael W. Vannier , Punam K. Saha , Ge Wang

Though U-Net has achieved tremendous success in medical image segmentation tasks, it lacks the ability to explicitly model long-range dependencies. Therefore, Vision Transformers have emerged as alternative segmentation structures recently,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Hongyi Wang , Shiao Xie , Lanfen Lin , Yutaro Iwamoto , Xian-Hua Han , Yen-Wei Chen , Ruofeng Tong

Computed Tomography (CT) plays a pivotal role in medical diagnosis; however, variability across reconstruction kernels hinders data-driven approaches, such as deep learning models, from achieving reliable and generalized performance. To…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Francesco Di Feola , Ludovica Pompilio , Cecilia Assolito , Valerio Guarrasi , Paolo Soda

Objective: Proton therapy is a precision-focused cancer treatment where accurate proton beam range monitoring is critical to ensure effective dose delivery. This can be achieved by prompt gamma detection with a Compton camera like the…

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

Medical Physics · Physics 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang
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