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We propose a supervised nonrigid image registration method, trained using artificial displacement vector fields (DVF), for which we propose and compare three network architectures. The artificial DVFs allow training in a fully supervised…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Hessam Sokooti , Bob de Vos , Floris Berendsen , Mohsen Ghafoorian , Sahar Yousefi , Boudewijn P. F. Lelieveldt , Ivana Isgum , Marius Staring

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

Purpose: To develop and evaluate a transformer-based deep learning model for the synthesis of nephrographic phase images in CT urography (CTU) examinations from the unenhanced and urographic phases. Materials and Methods: This retrospective…

Accurate synthesis of computed tomography (CT) images from magnetic resonance imaging (MRI) is clinically valuable for cranial applications such as attenuation correction, radiotherapy planning, and image-guided interventions. However,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Zhuoyao Xin , Yiren Zhang , Christopher Wu , Dong Liu , Chunming Gu , Elena Greco , Erik H. Middlebrooks , Jun Hua , Jia Guo

Deformable image registration, estimating the spatial transformation between different images, is an important task in medical imaging. Many previous studies have used learning-based methods for multi-stage registration to perform 3D image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jian-Qing Zheng , Ziyang Wang , Baoru Huang , Ngee Han Lim , Tonia Vincent , Bartlomiej W. Papiez

Medical image synthesis generates additional imaging modalities that are costly, invasive or harmful to acquire, which helps to facilitate the clinical workflow. When training pairs are substantially misaligned (e.g., lung MRI-CT pairs with…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Bowen Xin , Tony Young , Claire E Wainwright , Tamara Blake , Leo Lebrat , Thomas Gaass , Thomas Benkert , Alto Stemmer , David Coman , Jason Dowling

Unified multimodal models (UMMs) strive to consolidate visual understanding and visual generation within a single architecture. However, prevailing training paradigms independently optimize understanding via sparse text signals and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Songsong Yu , Yuxin Chen , Ying Shan , Yanwei Li

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Youbao Tang , Jinzheng Cai , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Hajar Emami , Ming Dong , Siamak Nejad-Davarani , Carri Glide-Hurst

Objective: Deformable brain MR image registration is challenging due to large inter-subject anatomical variation. For example, the highly complex cortical folding pattern makes it hard to accurately align corresponding cortical structures…

Computer Vision and Pattern Recognition · Computer Science 2019-02-07 Dongming Wei , Zhengwang Wu , Gang Li , Xiaohuan Cao , Dinggang Shen , Qian Wang

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

Recently, deep learning (DL)-based methods for the generation of synthetic computed tomography (sCT) have received significant research attention as an alternative to classical ones. We present here a systematic review of these methods by…

Medical Physics · Physics 2021-08-30 Maria Francesca Spadea , Matteo Maspero , Paolo Zaffino , Joao Seco

The synthesis of computed tomography (CT) from magnetic resonance imaging (MRI) and cone-beam CT (CBCT) plays a critical role in clinical treatment planning by enabling accurate anatomical representation in adaptive radiotherapy. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Siyuan Mei , Yan Xia , Fuxin Fan , Andreas Maier

Recently, more and more attention is drawn to the field of medical image synthesis across modalities. Among them, the synthesis of computed tomography (CT) image from T1-weighted magnetic resonance (MR) image is of great importance,…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Lei Xiang , Qian Wang , Xiyao Jin , Dong Nie , Yu Qiao , Dinggang Shen

Registration of longitudinal optical coherence tomography (OCT) images assists disease monitoring and is essential in image fusion applications. Mouse retinal OCT images are often collected for longitudinal study of eye disease models such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Accurate segmentation of the heart is essential for personalized blood flow simulations and surgical intervention planning. Segmentations need to be accurate in every spatial dimension, which is not ensured by segmenting data slice by…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Lee Jollans , Mariana Bustamante , Lilian Henriksson , Anders Persson , Tino Ebbers

Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis