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Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Mohamed S. Elmahdy , Laurens Beljaards , Sahar Yousefi , Hessam Sokooti , Fons Verbeek , U. A. van der Heide , Marius Staring

Supervised synthetic CT generation from CBCT requires registered training pairs, yet perfect registration between separately acquired scans remains unattainable. This registration bias propagates into trained models and corrupts standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lukas Zimmermann , Michael Rauter , Maximilian Schmid , Dietmar Georg , Barbara Knäusl

CBCTs in image-guided radiotherapy provide crucial anatomy information for patient setup and plan evaluation. Longitudinal CBCT image registration could quantify the inter-fractional anatomic changes. The purpose of this study is to propose…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Huiqiao Xie , Yang Lei , Yabo Fu , Tonghe Wang , Justin Roper , Jeffrey D. Bradley , Pretesh Patel , Tian Liu , Xiaofeng Yang

Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Zizhao Zhang , Lin Yang , Yefeng Zheng

Recently, joint registration and segmentation has been formulated in a deep learning setting, by the definition of joint loss functions. In this work, we investigate joining these tasks at the architectural level. We propose a registration…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Laurens Beljaards , Mohamed S. Elmahdy , Fons Verbeek , Marius Staring

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Complicated image registration is a key issue in medical image analysis, and deep learning-based methods have achieved better results than traditional methods. The methods include ConvNet-based and Transformer-based methods. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Runshi Zhang , Hao Mo , Junchen Wang , Bimeng Jie , Yang He , Nenghao Jin , Liang Zhu

Medical image synthesis remains challenging due to misalignment noise during training. Existing methods have attempted to address this challenge by incorporating a registration-guided module. However, these methods tend to overlook the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuanpu Li , Zeli Chen , Yiwen Zhang , Liming Zhong , Wei Yang

Registration plays an important role in medical image analysis. Deep learning-based methods have been studied for medical image registration, which leverage convolutional neural networks (CNNs) for efficiently regressing a dense deformation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Xiaoru Gao , GuoYan Zheng

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Joint image registration and segmentation has long been an active area of research in medical imaging. Here, we reformulate this problem in a deep learning setting using adversarial learning. We consider the case in which fixed and moving…

Image and Video Processing · Electrical Eng. & Systems 2019-07-01 Mohamed S. Elmahdy , Jelmer M. Wolterink , Hessam Sokooti , Ivana Išgum , Marius Staring

Cone beam computed tomography (CBCT) images can be used for dose calculation in adaptive radiation therapy (ART). The main challenges are the large artefacts and inaccurate Hounsfield unit (HU) values. Currently, deformed planning CT images…

Medical Physics · Physics 2019-09-04 Xiao Liang , Liyuan Chen , Dan Nguyen , Zhiguo Zhou , Xuejun Gu , Ming Yang , Jing Wang , Steve Jiang

Multimodal MR-US registration is critical for prostate cancer diagnosis. However, this task remains challenging due to significant modality discrepancies. Existing methods often fail to align critical boundaries while being overly sensitive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xudong Ma , Nantheera Anantrasirichai , Stefanos Bolomytis , Alin Achim

To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Snehashis Roy , John A. Butman , Dzung L. Pham

A total of twenty paired CT and MR images were used in this study to investigate two conditional generative adversarial networks, Pix2Pix, and Cycle GAN, for generating synthetic CT images for Headand Neck cancer cases. Ten of the patient…

Computer Vision and Pattern Recognition · Computer Science 2019-02-28 Peter Klages , Ilyes Benslimane , Sadegh Riyahi , Jue Jiang , Margie Hunt , Joe Deasy , Harini Veeraraghavan , Neelam Tyagi

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan