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Dengue fever is a mosquito-borne disease present in all Brazilian territory. Brazilian government, however, lacks an accurate early warning system to quickly predict future dengue outbreaks. Such system would help health authorities to plan…

Applications · Statistics 2016-08-12 Julio Albinati , Wagner Meira , Gisele Lobo Pappa

Dengue is a vector-borne disease transmitted by the mosquito Aedes aegypti. It has been observed that its incidence is strongly influenced by temperature and other abiotic factors like rainfall and humidity. In this work we compare the…

Populations and Evolution · Quantitative Biology 2016-05-23 Emilene Pliego Pliego , Jorge Velazquez-Castro , Andres Fraguela-Collar

In this study, we develop and analyze a deterministic two-strain host-vector model for dengue transmission that incorporates key immuno-epidemiological mechanisms, including temporary cross-immunity, antibody-dependent enhancement (ADE),…

Dynamical Systems · Mathematics 2026-01-13 Burcu Gürbüz , Aytül Gökçe , Joseph Páez Chávez , Thomas Götz

In regard to infectious diseases socioeconomic determinants are strongly associated with differential exposure and susceptibility however they are seldom accounted for by standard compartmental infectious disease models. These associations…

Applications · Statistics 2022-11-28 Alison C Hale , Jonathan M Read , Christopher P Jewell

Among the realistic ingredients to be considered in the computational modeling of infectious diseases, human mobility represents a crucial challenge both on the theoretical side and in view of the limited availability of empirical data. In…

Physics and Society · Physics 2010-02-04 Duygu Balcan , Vittoria Colizza , Bruno Goncalves , Hao Hu , Jose J. Ramasco , Alessandro Vespignani

This data paper describes and publicly releases this dataset (v1.0.0), published on Zenodo under DOI 10.5281/zenodo.18189192. Motivated by the need to increase the temporal granularity of originally monthly data to enable more effective…

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

Estimation of the long-term health effects of air pollution is a challenging task, especially when modelling small-area disease incidence data in an ecological study design. The challenge comes from the unobserved underlying spatial…

Methodology · Statistics 2013-05-24 Duncan Lee , Alastair Rushworth , Sujit K. Sahu

In multivariate longitudinal studies, associations between outcomes often exhibit time-varying and individual level heterogeneity, motivating the modeling of correlations as an explicit function of time and covariates. However, most…

Recent infectious disease outbreaks, such as the COVID-19 pandemic and the Zika epidemic in Brazil, have demonstrated both the importance and difficulty of accurately forecasting novel infectious diseases. When new diseases first emerge, we…

Machine Learning · Computer Science 2022-08-16 Kirstin Roster , Colm Connaughton , Francisco A. Rodrigues

The integration of mobile health (mHealth) devices into behavioral health research has fundamentally changed the way researchers and interventionalists are able to collect data as well as deploy and evaluate intervention strategies. In…

Methodology · Statistics 2021-12-17 Matthew D. Koslovsky , Emily T. Hebert , Michael S. Businelle , Marina Vannucci

We introduce a new tuberculosis (TB) mathematical model, with $25$ state-space variables where $15$ are evolution disease states (EDSs), which generalises previous models and takes into account the (seasonal) flux of populations between a…

Populations and Evolution · Quantitative Biology 2018-05-25 Eugenio M. Rocha , Cristiana J. Silva , Delfim F. M. Torres

Health outcomes depend on complex environmental and sociodemographic factors whose effects change over location and time. Only recently has fine-grained spatial and temporal data become available to study these effects, namely the MEDSAT…

Machine Learning · Computer Science 2025-01-07 Ishaan Maitra , Raymond Lin , Eric Chen , Jon Donnelly , Sanja Šćepanović , Cynthia Rudin

Exploiting the large amount of available data for addressing relevant social problems has been one of the key challenges in data mining. Such efforts have been recently named "data science for social good" and attracted the attention of…

Social and Information Networks · Computer Science 2015-10-21 Roberto C. S. N. P. Souza , Denise E. F de Brito , Renato M. Assunção , Wagner Meira

Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

Methodology · Statistics 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

Implementing insect monitoring systems provides an excellent opportunity to create accurate interventions for insect control. However, selecting the appropriate time for an intervention is still an open question due to the inherent…

Quantitative Methods · Quantitative Biology 2023-12-29 Gabriel R. Palma , Rodrigo F. Mello , Wesley A. C. Godoy , Eduardo Engel , Douglas Lau , Charles Markham , Rafael A. Moral

The conditional autoregressive model is a routinely used statistical model for areal data that arise from, for instances, epidemiological, socio-economic or ecological studies. Various multivariate conditional autoregressive models have…

Methodology · Statistics 2019-07-23 Ye Liang

We investigate a time-dependent spatial vector-host epidemic model with non-coincident domains for the vector and host populations. The host population resides in small non-overlapping sub-regions, while the vector population resides…

Analysis of PDEs · Mathematics 2018-09-12 W. E. Fitzgibbon , J. J. Morgan , Glenn F. Webb , Yixiang Wu

Background: Studies have shown that human mobility is an important factor in dengue epidemiology. Changes in mobility resulting from COVID-19 pandemic set up a real-life situation to test this hypothesis. Our objective was to evaluate the…

Predicting whether to expect a high incidence of infectious diseases is critical for health surveillance. In the epidemiology of dengue, environmental conditions can significantly impact the transmission of the virus. Utilizing…

Quantitative Methods · Quantitative Biology 2025-01-23 Daniel A. M. Villela