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We propose a marginal super-resolution (MSR) approach based on 2D convolutional neural networks (CNNs) for interpolating an anisotropic brain magnetic resonance scan along the highly under-sampled direction, which is assumed to axial…

Image and Video Processing · Electrical Eng. & Systems 2019-08-16 Cheng Peng , Wei-An Lin , Haofu Liao , Rama Chellappa , S. Kevin Zhou

Two-photon excited fluorescence (TPEF) microscopy and fluorescence lifetime imaging (FLIM) are powerful imaging techniques in bio-molecular science. The need for elaborate light sources for TPEF and speed limitations for FLIM, however,…

Instrumentation and Detectors · Physics 2018-10-12 Matthias Eibl , Sebastian Karpf , Hubertus Hakert , Daniel Weng , Robert Huber

Superconducting-nanowire single-photon detectors (SNSPDs) have enabled the realization of several quantum optics technologies thanks to their high detection efficiency, low dark-counts, and fast recovery time. However, the widespread use of…

Superconducting nanowire single photon detectors (SNSPDs) emerged in the last decade as a disruptive technology that features performance characteristics, such as high sensitivity, dynamic range and temporal accuracy, which are ideally…

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

We experimentally investigated the detection performance of highly disordered NbxTi1-xN based superconducting nanowire single photon detectors (SNSPDs). The dependence on the composition of the transition temperature Tc for NbxTi1-xN films…

Superconductivity · Physics 2022-10-28 Ruoyan Ma , Rui Shu , Xingyu Zhang , Aobo Yu , Huang Jia , You Xiao , Huiqin Yu , Xiaoyu Liu , Hao Li , Per Eklund , Xiaofu Zhang , Lixing You

To analyze the switching dynamics and output performance of a superconducting nanowire single photon detector (SNSPD), the nanowire is usually modelled as an inductor in series with a time-varying resistor induced by absorption of a photon.…

Applied Physics · Physics 2018-08-29 Qing-Yuan Zhao , Daniel F. Santavicca , Di Zhu , Brian Noble , Karl K. Berggren

We present the performance of a superconducting nanowire that can be operated in two detection modes: i) as a kinetic inductance detector (KID) or ii) as a single-photon detector (SPD). Two superconducting nanowires developed for use as…

Instrumentation and Detectors · Physics 2018-11-14 Edward Schroeder , Philip Mauskopf , Hamdi Mani , Sean Bryan , Karl K. Berggren , Di Zhu

Super-resolution microscopy normally requiring complex and cumbersome optics is not applicable for in situ imaging through a narrow channel. Here, we demonstrate single hair-thin multimode fiber (MMF) endoscope (less than 250 ${\mu}m$) for…

Light penetration depth in biological tissue is limited by tissue scattering. Correcting scattering becomes particularly challenging in scenarios with limited photon availability and when access to the transmission side of the scattering…

Optics · Physics 2025-02-12 Daniel Zepeda , Yucheng Li , Yi Xue

Silicon photomultipliers (SiPMs) are highly-sensitive photodetectors emerging as the technology of choice for many applications, including large high-energy physics experiments where they often are exposed to high radiation fluences. In…

Instrumentation and Detectors · Physics 2022-08-17 A. R. Altamura , F. Acerbi , C. Nociforo , V. Regazzoni , A. Mazzi , A. Gola

Two-photon (2P) microscopy is a powerful technique for deep-tissue fluorescence imaging; however, tissue scattering limits its effectiveness for depth imaging using conventional approaches. Despite typical strategies having been put forward…

Optics · Physics 2025-05-21 Lei Zhu , Bernhard Rauer , Hilton B. De Aguiar , Sylvain Gigan

Conventional LIDAR systems require hundreds or thousands of photon detections to form accurate depth and reflectivity images. Recent photon-efficient computational imaging methods are remarkably effective with only 1.0 to 3.0 detected…

Applications · Statistics 2019-11-13 Joshua Rapp , Vivek K Goyal

Light-sheet microscopes must compromise between field of view, optical sectioning, resolution, and detection efficiency. High-numerical-aperture (NA) detection objective lenses provide high resolution but their narrow depth of field fails…

Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Varun Mannam , Yide Zhang , Xiaotong Yuan , Scott Howard

We present the characterization of two-dimensionally arranged 64-pixel NbTiN superconducting nanowire single-photon detector array for spatially resolved photon detection. NbTiN films deposited on thermally oxidized Si substrates enabled…

Instrumentation and Detectors · Physics 2015-06-18 Shigehito Miki , Taro Yamashita , Zhen Wang , Hirotaka Terai

While single-photon counting is routinely achieved in the optical domain, operational single microwave photon detectors (SMPDs) have only recently been demonstrated. SMPDs are critical for sensing weak signals from incoherent emitters, with…

Two-Photon Microscopy has become an invaluable tool for biological and medical research, providing high sensitivity, molecular specificity, inherent three-dimensional sub-cellular resolution and deep tissue penetration. In terms of imaging…

Niobium Titanium nitride (NbTiN) based superconducting nanowire single photon detectors (SNSPDs) are known for their high performance across a wide spectral range, from the X-ray to the mid-infrared. Nonetheless, fabrication challenges and…

Quantum Physics · Physics 2026-02-19 C. Klein , S. Cohen , T. Descamps , A. Iovan , P. Zolotov , P. Vennéguès , I. Florea , F. Semond , V. Zwiller

Superconducting nanowire single-photon detectors (SNSPDs) are indispensable in fields such as quantum science and technology, astronomy, and biomedical imaging, where high detection efficiency, low dark count rates and high timing accuracy…