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We demonstrate a 16-pixel array of radio-frequency superconducting nanowire single-photon detectors with an integrated and scalable frequency-division multiplexing architecture, reducing the required bias and readout lines to a single…

Instrumentation and Detectors · Physics 2017-08-02 Steffen Doerner , Artem Kuzmin , Stefan Wuensch , Ilya Charaev , Florian Boes , Thomas Zwick , Michael Siegel

Imaging at depth in opaque materials has long been a challenge. Recently, wavefront shaping has enabled significant advance for deep imaging. Nevertheless, most non-invasive wavefront shaping methods require cameras, lack the sensitivity…

Deep neural networks (DNN) consist of layers of neurons interconnected by synaptic weights. A high bit-precision in weights is generally required to guarantee high accuracy in many applications. Minimizing error accumulation between layers…

The ability to achieve submillimter isotropic resolution diffusion MR imaging (dMRI) is critically important to study fine-scale brain structures, particularly in the cortex. One of the major challenges in performing submillimeter dMRI is…

Medical Physics · Physics 2020-12-08 Wei-Tang Chang , Khoi Minh Huynh , Pew-Thian Yap , Weili Lin

Simulation of detecting photoelectrons using multi-level multi-electron (MLME) finite-difference time-domain (FDTD) method with an application to near-field subwavelength imaging based on semiconductor nanophotodetector (NPD) array is…

Optics · Physics 2009-02-20 Ki Young Kim , Boyang Liu , Yingyan Huang , Seng-Tiong Ho

Fourier ptychographic microscopy (FPM) is a recently proposed computational imaging technique with both high resolution and wide field-of-view. In current FP experimental setup, the dark-field images with high-angle illuminations are easily…

Computer Vision and Pattern Recognition · Computer Science 2017-12-19 Yan Zhang , An Pan , Ming Lei , Baoli Yao

Fourier ptychography (FP) is a promising computational imaging technique that overcomes the physical space-bandwidth product (SBP) limit of a conventional microscope by applying angular diversity illuminations. However, to date, the…

Optics · Physics 2018-10-17 An Pan , Yan Zhang , Kai Wen , Maosen Li , Meiling Zhou , Junwei Min , Ming Lei , Baoli Yao

Functional near-infrared spectroscopy (fNIRS) is impacted by signal contamination from superficial hemodynamics. It is important to develop methods that account for such contamination and provide accurate measurements of cerebral…

Medical Physics · Physics 2026-03-27 Jodee Frias , Giles Blaney , Angelo Sassaroli , Sergio Fantini

This paper presents a detailed investigation of superconducting nanowire single-photon detectors (SNSPDs) biased with microwave and direct currents. We developed a hybrid detector, which allows the operation in the rf and dc operation mode.…

Instrumentation and Detectors · Physics 2019-03-27 Steffen Doerner , Artem Kuzmin , Stefan Wuensch , Michael Siegel

Spectral imaging in the mid-infrared (MIR) range provides simultaneous morphological and chemical information of a wide variety of samples. However, current MIR technologies struggle to produce high-definition images over a broad spectral…

This study found that plasmonic hotspots (HSs) between silver nanoparticles (NPs) and silver nanowires (NWs) generated two-photon excited emissions, including hyper-Rayleigh, hyper-Raman, and two-photon fluorescence of dye molecules with…

Optics · Physics 2025-07-22 Tamitake Itoh , Yuko S. Yamamoto

Mid-infrared (mid-IR) spectroscopy is a crucial workhorse for a plethora of analytical applications and is suitable for diverse materials, including gases, polymers or biological tissue. However, this technologically significant wavelength…

Optics · Physics 2022-02-23 Paul Kaufmann , Helen M. Chrzanowski , Aron Vanselow , Sven Ramelow

We report on the impact of the stoichiometry of superconducting MoSi thin films on the performance of superconducting nanowire single-photon detectors (SNSPDs). Specifically, we investigate the relation between the film parameters critical…

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

By harnessing quantum superposition and entanglement, remarkable progress has sprouted over the past three decades from different areas of research in communication computation and simulation. To further improve the processing ability of…

Applied Physics · Physics 2021-01-12 Ye Yang , Yaqing Jin , Xiao Xiang , Wei Li , Tao Liu , Shougang Zhang , Ruifang Dong , Ming Li

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical imaging technique for functional characterization of specimens owing to its enhanced spatial resolution and high specificity. Recently developed wide-field…

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

Signal Processing · Electrical Eng. & Systems 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

Scalable, high speed data transfer between cryogenic (0.1-4 K) and room temperature environments is instrumental in a broad range of fields including quantum computing, superconducting electronics, single photon imaging and space-based…

Applied Physics · Physics 2020-02-04 Marc de Cea , Emma E. Wollman , Amir H. Atabaki , Dodd J. Gray , Matthew D. Shaw , Rajeev J. Ram

We report on a free-space-coupled superconducting nanowire single-photon detector array developed for NASA's Deep Space Optical Communications project (DSOC). The array serves as the downlink detector for DSOC's primary ground receiver…

Progress in neuroscience constantly relies on the development of new techniques to investigate the complex dynamics of neuronal networks. An ongoing challenge is to achieve minimally-invasive and high-resolution observations of neuronal…