Related papers: Mathematical Analysis of FLASH Effect Models Based…
We introduce functional adaptive shrinkage (FASH), an empirical Bayes method for joint analysis of observation units in which each unit estimates an effect function at several values of a continuous condition variable. The ideas in this…
The aim of the thesis is the study of properties of solar flares via reconstruction of energy distributions of accelerated/heated electrons, diagnostics of flare plasma based on EUV and X-ray observations, as well as the estimation of the…
The 'standard solar' flare model collects all physical ingredients identified by multi-wavelength observations of our Sun: magnetic reconnection, fast particle acceleration and the resulting emission at various wavelengths, especially in…
Based on simplified models, formulae for determining particle energy losses due to Beamstarhlung in supercolliders are obtained. The developed semi-analytical approach can be useful for estimating the parameters of colliding beams under…
This article is motivated by the problem of inference on interactions among chemical exposures impacting human health outcomes. Chemicals often co-occur in the environment or in synthetic mixtures and as a result exposure levels can be…
In this work we develop and investigate mathematical and computational models that describe drug delivery from a contact lens during wear. Our models are designed to predict the dynamics of drug release from the contact lens and subsequent…
Estimating physical parameters or material properties from experimental observations is a common objective in many areas of physics and material science. In many experiments, especially in shock physics, radiography is the primary means of…
The analysis of data arising from environmental health studies which collect a large number of measures of exposure can benefit from using latent variable models to summarize exposure information. However, difficulties with estimation of…
For the reliable analysis and modelling of astrophysical, laser-produced and fusion plasmas, atomic data are required for a number of parameters, including energy levels, radiative rates and electron impact excitation rates. Such data are…
The potential outcomes framework serves as a fundamental tool for quantifying causal effects. The average dose-response function (also called the effect curve), denoted as (\mu(t)), is typically of interest when dealing with a continuous…
Cancer treatment with radiotherapy aims to kill tumor cells and spare healthy tissue.Thus,the experimentally observed sparing of healthy tissue by the FLASH effect during irradiations with ultra-high dose rates (UHDR) enables clinicians to…
There is evidence that the population of cells that experience fluctuating oxygen levels are more radioresistant than chronically hypoxic ones and hence, this population may determine radiotherapy (RT) response, in particular for…
Influence functions (IF) have been seen as a technique for explaining model predictions through the lens of the training data. Their utility is assumed to be in identifying training examples "responsible" for a prediction so that, for…
A major theme in constraint-based modeling is unifying experimental data, such as biochemical information about the reactions that can occur in a system or the composition and localization of enzyme complexes, with highthroughput data…
This paper deals with the classic radiotherapy dose fractionation problem for cancer tumors concerning the following goals: a) To maximize the effect of radiation on the tumor, restricting the effect produced to the organs at risk (healing…
Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful…
Effect of radiation-reaction force on the dynamics of a charged particle in an intense focused light wave is investigated using the physically appealing Hartemann-Luhmann equation of motion. It is found that, irrespective of the choice of…
The Flory-Huggins theory is a well-established lattice model that is commonly used to study the mixing of distinct chemical species. It can successfully predict phase separation phenomena in blends of incompatible materials. However, it is…
We present a novel model to estimate biological effects caused by artificial radiation exposure, Whack-a-mole (WAM) model. It is important to take account of the recovery effects during the time course of the cellular reactions. The…
The analysis method proposed in Ref. \cite{rotival07a} is applied to characterize halo properties in finite many-fermion systems. First, the versatility of the method is highlighted by applying it to light and medium-mass nuclei as well as…