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Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Anna S. Goncharova , Alf Honigmann , Florian Jug , Alexander Krull

Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise and bulk-motion noise, respectively. Because the cross-sectional retina has distinct features in OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jianlong Yang , Yan Hu , Liyang Fang , Jun Cheng , Jiang Liu

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle…

Deep learning-based denoising methods have shown powerful results for improving the signal-to-noise ratio of magnetic resonance (MR) images, mostly by leveraging supervised learning with clean ground truth. However, acquiring clean ground…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Juhyung Park , Dongwon Park , Sooyeon Ji , Hyeong-Geol Shin , Se Young Chun , Jongho Lee

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Spectroscopy represents the ideal observational method to maximally extract information from galaxies regarding their star formation and chemical enrichment histories. However, absorption spectra of galaxies prove rather challenging at high…

Instrumentation and Methods for Astrophysics · Physics 2025-10-10 Oliver Camilleri , Zahra Sharbaf , Ignacio Ferreras

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach

We propose a new deep learning approach for automatic detection and segmentation of fluid within retinal OCT images. The proposed framework utilizes both ResNet and Encoder-Decoder neural network architectures. When training the network, we…

Computer Vision and Pattern Recognition · Computer Science 2017-08-21 Dustin Morley , Hassan Foroosh , Saad Shaikh , Ulas Bagci

Optical coherence tomography (OCT) imaging from different camera devices causes challenging domain shifts and can cause a severe drop in accuracy for machine learning models. In this work, we introduce a minimal noise adaptation method…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Valentin Koch , Olle Holmberg , Hannah Spitzer , Johannes Schiefelbein , Ben Asani , Michael Hafner , Fabian J Theis

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Deep learning has been successfully applied to OCT segmentation. However, for data from different manufacturers and imaging protocols, and for different regions of interest (ROIs), it requires laborious and time-consuming data annotation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Haoran Zhang , Jianlong Yang , Ce Zheng , Shiqing Zhao , Aili Zhang

In medical imaging, there are clinically relevant segmentation tasks where the output mask is a projection to a subset of input image dimensions. In this work, we propose a novel convolutional neural network architecture that can…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Dmitrii Lachinov , Philipp Seeboeck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Magnetic resonance imaging (MRI) is a powerful noninvasive diagnostic imaging tool that provides unparalleled soft tissue contrast and anatomical detail. Noise contamination, especially in accelerated and/or low-field acquisitions, can…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Jiachen Tu , Yaokun Shi , Fan Lam

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Mohammadreza Saraei , Igor Kozak , Eung-Joo Lee

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Medical image acquisition is often intervented by unwanted noise that corrupts the information content. This paper introduces an unsupervised medical image denoising technique that learns noise characteristics from the available images and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Swati Rai , Jignesh S. Bhatt , S. K. Patra

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang
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