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Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Tan Hung Pham , Sripad Krishna Devalla , Aloysius Ang , Soh Zhi Da , Alexandre H. Thiery , Craig Boote , Ching-Yu Cheng , Victor Koh , Michael J. A. Girard

Image denoising is a fundamental task in computer vision, particularly in medical ultrasound (US) imaging, where speckle noise significantly degrades image quality. Although recent advancements in deep neural networks have led to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuesong Li , Nassir Navab , Zhongliang Jiang

With the advent of advances in self-supervised learning, paired clean-noisy data are no longer required in deep learning-based image denoising. However, existing blind denoising methods still require the assumption with regard to noise…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Kanggeun Lee , Won-Ki Jeong

Accurate segmentation of Optical Coherence Tomography (OCT) images is crucial for diagnosing and monitoring retinal diseases. However, the labor-intensive nature of pixel-level annotation limits the scalability of supervised learning for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jiaqi Yang , Nitish Mehta , Xiaoling Hu , Chao Chen , Chia-Ling Tsai

Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Zeyu Fu , Yang Sun , Xiangyu Zhang , Scott Stainton , Shaun Barney , Jeffry Hogg , William Innes , Satnam Dlay

Weakly supervised segmentation is an important problem in medical image analysis due to the high cost of pixelwise annotation. Prior methods, while often focusing on weak labels of 2D images, exploit few structural cues of volumetric…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Qian He , Shuailin Li , Xuming He

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Optical coherence tomography (OCT) is pivotal in corneal imaging for both surgical planning and diagnosis. However, high-speed acquisitions often degrade spatial resolution and increase speckle noise, posing challenges for accurate…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Yaning Wang , Jinglun Yu , Wenhan Guo , Ziyi Huang , Rosalinda Xiong , Yu Sun , Jin U. Kang

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jiahong Ouyang , Tejas Sudharshan Mathai , Kira Lathrop , John Galeotti

Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Yuxin Xie , Li Yu , Farhad Pakdaman , Moncef Gabbouj

We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…

We develop Self2Seg, a self-supervised method for the joint segmentation and denoising of a single image. To this end, we combine the advantages of variational segmentation with self-supervised deep learning. One major benefit of our method…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Nadja Gruber , Johannes Schwab , Noémie Debroux , Nicolas Papadakis , Markus Haltmeier

Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging technique that is highly valuable for ophthalmic diagnosis. However, speckles in AS-OCT images can often degrade the image quality and affect clinical…

Graphics · Computer Science 2023-07-03 Li Sanqian , Higashita Risa , Fu Huazhu , Li Heng , Niu Jingxuan , Liu Jiang

Microvascular anatomy is known to be involved in various neurological disorders. However, understanding these disorders is hindered by the lack of imaging modalities capable of capturing the comprehensive three-dimensional vascular network…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Etienne Chollet , Yaël Balbastre , Chiara Mauri , Caroline Magnain , Bruce Fischl , Hui Wang

Learning-based image reconstruction models, such as those based on the U-Net, require a large set of labeled images if good generalization is to be guaranteed. In some imaging domains, however, labeled data with pixel- or voxel-level label…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Sean I. Young , Adrian V. Dalca , Enzo Ferrante , Polina Golland , Christopher A. Metzler , Bruce Fischl , Juan Eugenio Iglesias

Accurate medical image segmentation is of utmost importance for enabling automated clinical decision procedures. However, prevailing supervised deep learning approaches for medical image segmentation encounter significant challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Sanaz Karimijafarbigloo , Reza Azad , Amirhossein Kazerouni , Yury Velichko , Ulas Bagci , Dorit Merhof

In this paper, the problem of image super-resolution for Optical Coherence Tomography (OCT) has been addressed. Due to the motion artifacts, OCT imaging is usually done with a low sampling rate and the resulting images are often noisy and…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Farnaz Sedighin , Andrzej Cichocki , Hossein Rabbani