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This paper proposes a novel framework for accelerating support vector clustering. The proposed method first computes much smaller compressed data sets while preserving the key cluster properties of the original data sets based on a novel…

Machine Learning · Computer Science 2023-05-16 Yuxuan Song , Yongyu Wang

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Clustering, as an unsupervised technique, plays a pivotal role in various data analysis applications. Among clustering algorithms, Spectral Clustering on Euclidean Spaces has been extensively studied. However, with the rapid evolution of…

Machine Learning · Computer Science 2024-12-09 Sagar Ghosh , Swagatam Das

Health monitoring applications increasingly rely on machine learning techniques to learn end-user physiological and behavioral patterns in everyday settings. Considering the significant role of wearable devices in monitoring human body…

Machine Learning · Computer Science 2022-08-03 Sina Shahhosseini , Yang Ni , Hamidreza Alikhani , Emad Kasaeyan Naeini , Mohsen Imani , Nikil Dutt , Amir M. Rahmani

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

This paper addresses the clustering of data in the hyperdimensional computing (HDC) domain. In prior work, an HDC-based clustering framework, referred to as HDCluster, has been proposed. However, the performance of the existing HDCluster is…

Machine Learning · Computer Science 2024-04-19 Lulu Ge , Keshab K. Parhi

Embedded systems continue to rapidly proliferate in diverse fields, including medical devices, autonomous vehicles, and more generally, the Internet of Things (IoT). Many embedded systems require application-specific hardware components to…

Hardware Architecture · Computer Science 2024-04-24 Yuchao Liao , Tosiron Adegbija , Roman Lysecky

Computing with high-dimensional (HD) vectors, also referred to as $\textit{hypervectors}$, is a brain-inspired alternative to computing with scalars. Key properties of HD computing include a well-defined set of arithmetic operations on…

Signal Processing · Electrical Eng. & Systems 2018-04-25 Fabio Montagna , Abbas Rahimi , Simone Benatti , Davide Rossi , Luca Benini

Hyperdimensional Computing (HDC) is an emerging computational framework that mimics important brain functions by operating over high-dimensional vectors, called hypervectors (HVs). In-memory computing implementations of HDC are desirable…

Emerging Technologies · Computer Science 2021-06-24 Arman Kazemi , Mohammad Mehdi Sharifi , Zhuowen Zou , Michael Niemier , X. Sharon Hu , Mohsen Imani

Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of…

Spectral clustering methods have gained widespread recognition for their effectiveness in clustering high-dimensional data. Among these techniques, constrained spectral clustering has emerged as a prominent approach, demonstrating enhanced…

Machine Learning · Computer Science 2024-04-05 Swarup Ranjan Behera , Vijaya V. Saradhi

Energy-efficient medical data classification is essential for modern disease screening, particularly in home and field healthcare where embedded devices are prevalent. While deep learning models achieve state-of-the-art accuracy, their…

Machine Learning · Computer Science 2026-03-24 Jianglan Wei , Zhenyu Zhang , Pengcheng Wang , Mingjie Zeng , Zhigang Zeng

Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

Dynamic programming (DP) based algorithms are essential yet compute-intensive parts of numerous bioinformatics pipelines, which typically involve populating a 2-D scoring matrix based on a recursive formula, optionally followed by a…

Hardware Architecture · Computer Science 2024-11-07 Yingqi Cao , Anshu Gupta , Jason Liang , Yatish Turakhia

Hardware specialization is becoming a key enabler of energyefficient performance. Future systems will be increasingly heterogeneous, integrating multiple specialized and programmable accelerators, each with different memory demands.…

Hardware Architecture · Computer Science 2021-04-26 Johnathan Alsop , Weon Taek Na , Matthew D. Sinclair , Samuel Grayson , Sarita V. Adve

We propose a method for the unsupervised clustering of hyperspectral images based on spatially regularized spectral clustering with ultrametric path distances. The proposed method efficiently combines data density and geometry to…

Computer Vision and Pattern Recognition · Computer Science 2020-04-13 Shukun Zhang , James M. Murphy

Point-based 3D point cloud models employ computation and memory intensive mapping functions alongside NN layers for classification/segmentation, and are executed on server-grade GPUs. The sparse, and unstructured nature of 3D point cloud…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-30 Amur Saqib Pal , Muhammad Mohsin Ghaffar , Faisal Shafait , Christian Weis , Norbert Wehn

Small-molecule identification from tandem mass spectrometry (MS/MS) remains a bottleneck in untargeted settings where spectral libraries are incomplete. While deep learning offers a solution, current approaches typically fall into two…

Machine Learning · Computer Science 2026-03-05 Yinkai Wang , Yan Zhou Chen , Xiaohui Chen , Li-Ping Liu , Soha Hassoun

Hyperdimensional (HD) computing is built upon its unique data type referred to as hypervectors. The dimension of these hypervectors is typically in the range of tens of thousands. Proposed to solve cognitive tasks, HD computing aims at…

Machine Learning · Computer Science 2020-06-08 Lulu Ge , Keshab K. Parhi

Database-search algorithms, that deduce peptides from Mass Spectrometry (MS) data, have tried to improve the computational efficiency to accomplish larger, and more complex systems biology studies. Existing serial, and high-performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-08 Muhammad Haseeb , Fahad Saeed