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A mixture of joint generalized hyperbolic distributions (MJGHD) is introduced for asymmetric clustering for high-dimensional data. The MJGHD approach takes into account the cluster-specific subspace, thereby limiting the number of…

Methodology · Statistics 2018-11-02 Yang Tang , Ryan P. Browne , Paul D. McNicholas

Spectral clustering is a leading clustering method. Two of its major shortcomings are the disjoint optimization process and the limited representation capacity. To address these issues, we propose a deep spectral clustering model (named…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Wengang Guo , Wei Ye , Chunchun Chen , Xin Sun , Christian Böhm , Claudia Plant , Susanto Rahardja

Due to its flexible architecture, FPGAs support unique, deep hardware pipeline implementations for accelerating HPC applications. However, these devices are quite new in the HPC space, and thus, have been scarcely explored outside some…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-28 Nicolas Lee Guidotti

For open vocabulary recognition of ingredients in food images, segmenting the ingredients is a crucial step. This paper proposes a novel approach that explores PCA-based feature representations of image pixels using a convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Ying Dai

Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine…

Quantitative Methods · Quantitative Biology 2023-03-14 Michael J. MacCoss , Javier Alfaro , Meni Wanunu , Danielle A. Faivre , Nikolai Slavov

The essence of precision oncology lies in its commitment to tailor targeted treatments and care measures to each patient based on the individual characteristics of the tumor. The inherent heterogeneity of tumors necessitates gathering…

Quantitative Methods · Quantitative Biology 2024-07-01 Huajun Zhou , Fengtao Zhou , Chenyu Zhao , Yingxue Xu , Luyang Luo , Hao Chen

This paper introduces a novel formulation of the clustering problem, namely the Minimum Sum-of-Squares Clustering of Infinitely Tall Data (MSSC-ITD), and presents HPClust, an innovative set of hybrid parallel approaches for its effective…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-26 Ravil Mussabayev , Rustam Mussabayev

Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…

Instrumentation and Detectors · Physics 2018-12-31 Yichen Wu , Aniruddha Ray , Qingshan Wei , Alborz Feizi , Xin Tong , Eva Chen , Yi Luo , Aydogan Ozcan

In conventional federated hyperdimensional computing (HDC), training larger models usually results in higher predictive performance but also requires more computational, communication, and energy resources. If the system resources are…

Machine Learning · Computer Science 2023-06-05 Nikita Zeulin , Olga Galinina , Nageen Himayat , Sergey Andreev

Mass spectrometry provides a high-throughput approach to identify proteins in biological samples. A key step in the analysis of mass spectrometry data is to identify the peptide sequence that, most probably, gave rise to each observed…

Applications · Statistics 2013-01-14 Qunhua Li , Jimmy K. Eng , Matthew Stephens

Background. Subdural hematoma (SDH) is a common neurosurgical emergency, with increasing incidence in aging populations. Rapid and accurate identification is essential to guide timely intervention, yet existing automated tools focus…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Vasiliki Stoumpou , Rohan Kumar , Bernard Burman , Diego Ojeda , Tapan Mehta , Dimitris Bertsimas

Modern data-intensive applications demand high computation capabilities with strict power constraints. Unfortunately, such applications suffer from a significant waste of both execution cycles and energy in current computing systems due to…

Hardware Architecture · Computer Science 2021-07-06 Gagandeep Singh , Mohammed Alser , Damla Senol Cali , Dionysios Diamantopoulos , Juan Gómez-Luna , Henk Corporaal , Onur Mutlu

The identification and property prediction of chemical molecules is of central importance in the advancement of drug discovery and material science, where the tandem mass spectrometry technology gives valuable fragmentation cues in the form…

Artificial Intelligence · Computer Science 2026-04-14 Yunhua Zhong , Yixuan Tang , Yifan Li , Jie Yang , Pan Liu , Jun Xia

Disruptive technologies provides unparalleled opportunities to contribute to the identifications of many aspects in pervasive healthcare, from the adoption of the Internet of Things through to Machine Learning (ML) techniques. As a powerful…

Machine Learning · Computer Science 2021-12-01 Zheming Zuo , Jie Li , Han Xu , Noura Al Moubayed

Mixed-precision neural networks (MPNNs) that enable the use of just enough data width for a deep learning task promise significant advantages of both inference accuracy and computing overhead. FPGAs with fine-grained reconfiguration…

Hardware Architecture · Computer Science 2023-08-23 Erjing Luo , Haitong Huang , Cheng Liu , Guoyu Li , Bing Yang , Ying Wang , Huawei Li , Xiaowei Li

Multispectral transmission imaging provides strong benefits for early breast cancer screening. The frame accumulation method addresses the challenge of low grayscale and signal-to-noise ratio resulting from the strong absorption and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-04 Jiatong Li , Gang Li , Nan Su Su Win , Ling Lin

Protein structure prediction models such as AlphaFold3 (AF3) push the frontier of biomolecular modeling by incorporating science-informed architectural changes to the transformer architecture. However, these advances come at a steep system…

Biomolecules · Quantitative Biology 2025-06-27 Hoa La , Ahan Gupta , Alex Morehead , Jianlin Cheng , Minjia Zhang

Mass spectrometry is a widely used method to study molecules and processes in medicine, life sciences, chemistry, catalysis, and industrial product quality control, among many other applications. One of the main features of some mass…

Chemical Physics · Physics 2024-07-02 Daniil A. Boiko , Valentine P. Ananikov

Cervical cancer remains a significant health problem, especially in developing countries. Early detection is critical for effective treatment. Convolutional neural networks (CNN) have shown promise in automated cervical cancer screening,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Ach Khozaimi , Isnani Darti , Syaiful Anam , Wuryansari Muharini Kusumawinahyu

Brain-inspired hyperdimensional computing (HDC) has been recently considered a promising learning approach for resource-constrained devices. However, existing approaches use static encoders that are never updated during the learning…

Machine Learning · Computer Science 2023-04-13 Junyao Wang , Sitao Huang , Mohsen Imani
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