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Related papers: Generalization in medical AI: a perspective on dev…

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Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

The recent achievements of Deep Learning rely on the test data being similar in distribution to the training data. In an ideal case, Deep Learning models would achieve Out-of-Distribution (OoD) Generalization, i.e. reliably make predictions…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Antoine Sanner , Camila Gonzalez , Anirban Mukhopadhyay

The goal of domain generalization algorithms is to predict well on distributions different from those seen during training. While a myriad of domain generalization algorithms exist, inconsistencies in experimental conditions -- datasets,…

Machine Learning · Computer Science 2020-07-06 Ishaan Gulrajani , David Lopez-Paz

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Generalization capability to unseen domains is crucial for machine learning models when deploying to real-world conditions. We investigate the challenging problem of domain generalization, i.e., training a model on multi-domain source data…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Qi Dou , Daniel C. Castro , Konstantinos Kamnitsas , Ben Glocker

Explainable Artificial Intelligence (XAI) is a rising field in AI. It aims to produce a demonstrative factor of trust, which for human subjects is achieved through communicative means, which Machine Learning (ML) algorithms cannot solely…

Machine Learning · Computer Science 2021-03-09 Jamie Andrew Duell

Real-world medical image segmentation has tremendous long-tailed complexity of objects, among which tail conditions correlate with relatively rare diseases and are clinically significant. A trustworthy medical AI algorithm should…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Mingze Yuan , Yingda Xia , Hexin Dong , Zifan Chen , Jiawen Yao , Mingyan Qiu , Ke Yan , Xiaoli Yin , Yu Shi , Xin Chen , Zaiyi Liu , Bin Dong , Jingren Zhou , Le Lu , Ling Zhang , Li Zhang

Artificial intelligence shows promise for solving many practical societal problems in areas such as healthcare and transportation. However, the current mechanisms for AI model diffusion such as Github code repositories, academic project…

Computers and Society · Computer Science 2020-03-04 Abhishek Kumar , Benjamin Finley , Tristan Braud , Sasu Tarkoma , Pan Hui

Data-driven medical AI is traditionally formulated as a discriminative mapping from input $X$ to output $Y$ via a learned function $f$, which does not generalize well across heterogeneous data and modalities encountered in real-world…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Hantao Zhang , Weidong Guo , Yuhe Liu , Jiancheng Yang , Sathvik Bhagavan , Danli Shi , Mingda Xu , Pascal Fua

Constructing a robust model that can effectively generalize to test samples under distribution shifts remains a significant challenge in the field of medical imaging. The foundational models for vision and language, pre-trained on extensive…

The growing reliance on Artificial Intelligence (AI) in critical domains such as healthcare demands robust mechanisms to ensure the trustworthiness of these systems, especially when faced with unexpected or anomalous inputs. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Max Gutbrod , David Rauber , Danilo Weber Nunes , Christoph Palm

Recently, we have witnessed great progress in the field of medical imaging classification by adopting deep neural networks. However, the recent advanced models still require accessing sufficiently large and representative datasets for…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Haoliang Li , YuFei Wang , Renjie Wan , Shiqi Wang , Tie-Qiang Li , Alex C. Kot

This large scale study focuses on quantifying what X-rays diagnostic prediction tasks generalize well across multiple different datasets. We present evidence that the issue of generalization is not due to a shift in the images but instead a…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Joseph Paul Cohen , Mohammad Hashir , Rupert Brooks , Hadrien Bertrand

Machine learning (ML) systems in natural language processing (NLP) face significant challenges in generalizing to out-of-distribution (OOD) data, where the test distribution differs from the training data distribution. This poses important…

Computation and Language · Computer Science 2023-05-24 Linyi Yang , Yaoxiao Song , Xuan Ren , Chenyang Lyu , Yidong Wang , Lingqiao Liu , Jindong Wang , Jennifer Foster , Yue Zhang

Domain generalization has become a critical challenge in predictive healthcare, where different patient groups often exhibit shifting data distributions that degrade model performance. Still, regular domain generalization approaches often…

Machine Learning · Computer Science 2026-02-16 Pengfei Hu , Xiaoxue Han , Fei Wang , Yue Ning

Test-time scaling has recently emerged as a promising approach for enhancing the reasoning capabilities of large language models or vision-language models during inference. Although a variety of test-time scaling strategies have been…

Computation and Language · Computer Science 2025-06-17 Gyutaek Oh , Seoyeon Kim , Sangjoon Park , Byung-Hoon Kim

Machine Learning (ML) has been a foundational topic in artificial intelligence (AI), providing both theoretical groundwork and practical tools for its exciting advancements. From ResNet for visual recognition to Transformer for…

Machine Learning · Computer Science 2025-12-30 Zhuo Huang

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Out-of-distribution (O.O.D.) generalization remains to be a key challenge for real-world machine learning systems. We describe a method for O.O.D. generalization that, through training, encourages models to only preserve features in the…

Machine Learning · Computer Science 2022-08-09 Arjun Ashok , Chaitanya Devaguptapu , Vineeth Balasubramanian
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