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Traditional machine learning paradigms are based on the assumption that both training and test data follow the same statistical pattern, which is mathematically referred to as Independent and Identically Distributed ($i.i.d.$). However, in…

Machine Learning · Computer Science 2023-07-28 Jiashuo Liu , Zheyan Shen , Yue He , Xingxuan Zhang , Renzhe Xu , Han Yu , Peng Cui

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

Learning the ability to generalize knowledge between similar contexts is particularly important in medical imaging as data distributions can shift substantially from one hospital to another, or even from one machine to another. To…

Computer Vision and Pattern Recognition · Computer Science 2023-11-13 Steven Korevaar , Ruwan Tennakoon , Ricky O'Brien , Dwarikanath Mahapatra , Alireza Bab-Hadiasha

Machine learning (ML) is a promising tool for the detection of phases of matter. However, ML models are also known for their black-box construction, which hinders understanding of what they learn from the data and makes their application to…

The development of large-scale artificial intelligence (AI) models is influencing neuroscience research by enabling end-to-end learning from raw brain signals and neural data. In this paper, we review applications of large-scale AI models…

Domain generalization aims at training machine learning models to perform robustly across different and unseen domains. Several recent methods use multiple datasets to train models to extract domain-invariant features, hoping to generalize…

Machine Learning · Computer Science 2021-05-19 Mattia Segu , Alessio Tonioni , Federico Tombari

A large language model's (LLM's) out-of-distribution (OOD) generalisation ability is crucial to its deployment. Previous work assessing LLMs' generalisation performance, however, typically focuses on a single out-of-distribution dataset.…

Computation and Language · Computer Science 2025-12-09 Matteo Boglioni , Andrea Sgobbi , Gabriel Tavernini , Francesco Rita , Marius Mosbach , Tiago Pimentel

Machine learning (ML) has demonstrated significant promise in accelerating drug design. Active ML-guided optimization of therapeutic molecules typically relies on a surrogate model predicting the target property of interest. The model…

Deep Metric Learning (DML) aims to find representations suitable for zero-shot transfer to a priori unknown test distributions. However, common evaluation protocols only test a single, fixed data split in which train and test classes are…

Machine Learning · Computer Science 2021-11-30 Timo Milbich , Karsten Roth , Samarth Sinha , Ludwig Schmidt , Marzyeh Ghassemi , Björn Ommer

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

Medical term normalization consists in mapping a piece of text to a large number of output classes. Given the small size of the annotated datasets and the extremely long tail distribution of the concepts, it is of utmost importance to…

Computation and Language · Computer Science 2022-11-04 Beatrice Portelli , Simone Scaboro , Enrico Santus , Hooman Sedghamiz , Emmanuele Chersoni , Giuseppe Serra

Graph machine learning (GML) has been successfully applied across a wide range of tasks. Nonetheless, GML faces significant challenges in generalizing over out-of-distribution (OOD) data, which raises concerns about its wider applicability.…

Machine Learning · Computer Science 2024-10-17 Jing Ma

A ubiquitous challenge in machine learning is the problem of domain generalisation. This can exacerbate bias against groups or labels that are underrepresented in the datasets used for model development. Model bias can lead to unintended…

This paper introduces the first generalization and adaptation benchmark using machine learning for evaluating out-of-distribution performance of electromyography (EMG) classification algorithms. The ability of an EMG classifier to handle…

Machine Learning · Computer Science 2024-11-05 Jehan Yang , Maxwell Soh , Vivianna Lieu , Douglas J Weber , Zackory Erickson

Algorithmic generalization in machine learning refers to the ability to learn the underlying algorithm that generates data in a way that generalizes out-of-distribution. This is generally considered a difficult task for most machine…

Machine Learning · Computer Science 2024-01-17 Simon Ouellette , Rolf Pfister , Hansueli Jud

Deep Learning systems have achieved great success in the past few years, even surpassing human intelligence in several cases. As of late, they have also established themselves in the biomedical and healthcare domains, where they have shown…

Machine Learning · Computer Science 2022-10-06 Aristotelis Ballas , Christos Diou

Although recent advances in machine learning have shown its success to learn from independent and identically distributed (IID) data, it is vulnerable to out-of-distribution (OOD) data in an open world. Domain generalization (DG) deals with…

Machine Learning · Computer Science 2024-05-14 Thai-Hoang Pham , Xueru Zhang , Ping Zhang

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Vision foundation models are increasingly moving beyond 2D to volumetric domains such as 3D medical imaging, where unified pretraining across different imaging modalities (i.e. CT, MRI, and PET) could provide foundational models for diverse…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Ho Hin Lee , Dongna Du , Chu Wang , Yuankai Huo , Shi Gu , James C. Gee , Yifan Wu

Artificial Intelligence (AI) and Machine-Learning (ML) models have been increasingly used in medical products, such as medical device software. General considerations on the statistical aspects for the evaluation of AI/ML-enabled medical…

Methodology · Statistics 2023-03-10 Feiming Chen , Hong Laura Lu , Arianna Simonetti