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Related papers: BioInstruct: Instruction Tuning of Large Language …

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To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Computation and Language · Computer Science 2026-04-21 Yuxin Xiao , Shujian Zhang , Wenxuan Zhou , Marzyeh Ghassemi , Sanqiang Zhao

Recent work has shown the immense potential of synthetically generated datasets for training large language models (LLMs), especially for acquiring targeted skills. Current large-scale math instruction tuning datasets such as MetaMathQA (Yu…

Computation and Language · Computer Science 2024-11-05 Shubham Toshniwal , Ivan Moshkov , Sean Narenthiran , Daria Gitman , Fei Jia , Igor Gitman

Large "instruction-tuned" language models (i.e., finetuned to respond to instructions) have demonstrated a remarkable ability to generalize zero-shot to new tasks. Nevertheless, they depend heavily on human-written instruction data that is…

Computation and Language · Computer Science 2023-05-29 Yizhong Wang , Yeganeh Kordi , Swaroop Mishra , Alisa Liu , Noah A. Smith , Daniel Khashabi , Hannaneh Hajishirzi

Medical systematic reviews can be very costly and resource intensive. We explore how Large Language Models (LLMs) can support and be trained to perform literature screening when provided with a detailed set of selection criteria.…

Computation and Language · Computer Science 2023-08-15 Ambrose Robinson , William Thorne , Ben P. Wu , Abdullah Pandor , Munira Essat , Mark Stevenson , Xingyi Song

Prompting Large Language Models (LLMs), or providing context on the expected model of operation, is an effective way to steer the outputs of such models to satisfy human desiderata after they have been trained. But in rapidly evolving…

Machine Learning · Computer Science 2025-08-08 Younwoo Choi , Muhammad Adil Asif , Ziwen Han , John Willes , Rahul G. Krishnan

Recent advancements in open-source code large language models (LLMs) have been driven by fine-tuning on the data generated from powerful closed-source LLMs, which are expensive to obtain. This paper explores whether it is possible to use a…

Computation and Language · Computer Science 2024-12-17 Yutong Wu , Di Huang , Wenxuan Shi , Wei Wang , Lingzhe Gao , Shihao Liu , Ziyuan Nan , Kaizhao Yuan , Rui Zhang , Xishan Zhang , Zidong Du , Qi Guo , Yewen Pu , Dawei Yin , Xing Hu , Yunji Chen

The ability of large language models (LLMs) to follow instructions is crucial to real-world applications. Despite recent advances, several studies have highlighted that LLMs struggle when faced with challenging instructions, especially…

Computation and Language · Computer Science 2024-04-04 Haoran Sun , Lixin Liu , Junjie Li , Fengyu Wang , Baohua Dong , Ran Lin , Ruohui Huang

Large Language Models (LLMs) have demonstrated remarkable performance across various natural language tasks, marking significant strides towards general artificial intelligence. While general artificial intelligence is leveraged by…

Computation and Language · Computer Science 2023-10-31 Yizhe Yang , Huashan Sun , Jiawei Li , Runheng Liu , Yinghao Li , Yuhang Liu , Heyan Huang , Yang Gao

Large language models demonstrate impressive proficiency in language understanding and generation. Nonetheless, training these models from scratch, even the least complex billion-parameter variant demands significant computational resources…

Artificial Intelligence · Computer Science 2025-01-10 Danyal Aftab , Steven Davy

Large language models (LLMs) demonstrate remarkable ability to comprehend, reason, and generate following nature language instructions. However, the development of LLMs has been primarily focused on high-resource languages, such as English,…

This paper introduces MM-Instruct, a large-scale dataset of diverse and high-quality visual instruction data designed to enhance the instruction-following capabilities of large multimodal models (LMMs). While existing visual instruction…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Jihao Liu , Xin Huang , Jinliang Zheng , Boxiao Liu , Jia Wang , Osamu Yoshie , Yu Liu , Hongsheng Li

Following the initial flourishing of large language models (LLMs), there has been a surge in proposed large vision-language models (LVLMs) that integrate LLMs with vision capabilities. However, it has been observed that LVLMs, after tuning…

Computation and Language · Computer Science 2025-12-30 Daiki Shiono , Shumpei Miyawaki , Ryota Tanaka , Jun Suzuki

Supervised Fine-Tuning (SFT) is essential for training large language models (LLMs), significantly enhancing critical capabilities such as instruction following and in-context learning. Nevertheless, creating suitable training datasets…

Computation and Language · Computer Science 2025-09-16 Iman Barati , Mostafa Amiri , Heshaam Faili

Instruction-finetuning (IFT) has become crucial in aligning Large Language Models (LLMs) with diverse human needs and has shown great potential in medical applications. However, previous studies mainly fine-tune LLMs on biomedical datasets…

Computation and Language · Computer Science 2025-04-02 Xinlu Zhang , Chenxin Tian , Xianjun Yang , Lichang Chen , Zekun Li , Linda Ruth Petzold

There is a consensus that instruction fine-tuning of LLMs requires high-quality data, but what are they? LIMA (NeurIPS 2023) and AlpaGasus (ICLR 2024) are state-of-the-art methods for selecting such high-quality examples, either via manual…

Computation and Language · Computer Science 2024-06-05 Hao Zhao , Maksym Andriushchenko , Francesco Croce , Nicolas Flammarion

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

Biomolecules · Quantitative Biology 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

Large Language Models (LLMs) have demonstrated remarkable instruction-following capabilities across various applications. However, their performance in multilingual settings lacks systematic investigation, with existing evaluations lacking…

Computation and Language · Computer Science 2025-11-04 Zhenyu Li , Kehai Chen , Yunfei Long , Xuefeng Bai , Yaoyin Zhang , Xuchen Wei , Juntao Li , Min Zhang

Instruction tuning has emerged to enhance the capabilities of large language models (LLMs) to comprehend instructions and generate appropriate responses. Existing methods either manually annotate or employ LLM (e.g., GPT-series) to generate…

Computation and Language · Computer Science 2023-10-27 Da Yin , Xiao Liu , Fan Yin , Ming Zhong , Hritik Bansal , Jiawei Han , Kai-Wei Chang

Instruction tuning has become essential for adapting large language models (LLMs) to follow domain-specific prompts. Yet, in specialized fields such as medicine, the scarcity of high-quality French instruction data limits effective…

Computation and Language · Computer Science 2026-03-10 Ikram Belmadani , Oumaima El Khettari , Pacôme Constant dit Beaufils , Benoit Favre , Richard Dufour

Large language models (LLMs) and their variants have shown extraordinary efficacy across numerous downstream natural language processing (NLP) tasks, which has presented a new vision for the development of NLP. Despite their remarkable…

Computation and Language · Computer Science 2024-01-18 Yazhou Zhang , Mengyao Wang , Youxi Wu , Prayag Tiwari , Qiuchi Li , Benyou Wang , Jing Qin
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