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Large Language Models (LLMs) have demonstrated impressive capabilities in creative tasks such as storytelling and E-mail generation. However, as LLMs are primarily trained on final text results rather than intermediate revisions, it might…

Computation and Language · Computer Science 2023-12-21 Lei Shu , Liangchen Luo , Jayakumar Hoskere , Yun Zhu , Yinxiao Liu , Simon Tong , Jindong Chen , Lei Meng

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

Large Language Models (LLMs) have recently gained attention in the life sciences due to their capacity to model, extract, and apply complex biological information. Beyond their classical use as chatbots, these systems are increasingly used…

Computation and Language · Computer Science 2025-07-03 Baqer M. Merzah , Tania Taami , Salman Asoudeh , Saeed Mirzaee , Amir reza Hossein pour , Amir Ali Bengari

While large language models (LLMs) have demonstrated remarkable versatility across a wide range of general tasks, their effectiveness often diminishes in domain-specific applications due to inherent knowledge gaps. Moreover, their…

Artificial Intelligence · Computer Science 2025-11-21 Hanzhi Yan , Qin Lu , Xianqiao Wang , Xiaoming Zhai , Tianming Liu , He Li

Background and Objective: Biomedical Named Entity Recognition (BioNER) is a foundational task in medical informatics, crucial for downstream applications like drug discovery and clinical trial matching. However, adapting general-domain…

Computation and Language · Computer Science 2025-12-30 Jian Chen , Leilei Su , Cong Sun

Instruction-tuned Large Language Models (LLMs) have recently showcased remarkable ability to generate fitting responses to natural language instructions. However, an open research question concerns the inherent biases of trained models and…

Computation and Language · Computer Science 2023-09-08 Patrick Haller , Ansar Aynetdinov , Alan Akbik

Process mining is increasingly using textual information associated with events to tackle tasks such as anomaly detection and process discovery. Such semantics-aware process mining focuses on what behavior should be possible in a process…

Computation and Language · Computer Science 2025-08-25 Vira Pyrih , Adrian Rebmann , Han van der Aa

Instruction tuning has significantly advanced large language models (LLMs) such as ChatGPT, enabling them to align with human instructions across diverse tasks. However, progress in open vision-language models (VLMs) has been limited due to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Lei Li , Yuwei Yin , Shicheng Li , Liang Chen , Peiyi Wang , Shuhuai Ren , Mukai Li , Yazheng Yang , Jingjing Xu , Xu Sun , Lingpeng Kong , Qi Liu

Recent advances in table understanding have focused on instruction-tuning large language models (LLMs) for table-related tasks. However, existing research has overlooked the impact of hyperparameter choices, and also lacks a comprehensive…

Computation and Language · Computer Science 2025-08-05 Naihao Deng , Rada Mihalcea

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

The integration of large language models (LLMs) into automated algorithm design has shown promising potential. A prevalent approach embeds LLMs within search routines to iteratively generate and refine candidate algorithms. However, most…

Machine Learning · Computer Science 2026-05-20 Fei Liu , Rui Zhang , Xi Lin , Zhichao Lu , Qingfu Zhang

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Building a general-purpose task model similar to ChatGPT has been an important research direction for gene large language models. Instruction fine-tuning is a key component in building ChatGPT, but existing instructions are primarily based…

Genomics · Quantitative Biology 2024-12-03 Wang Liang

While large language models (LLMs) have exhibited impressive instruction-following capabilities, it is still unclear whether and to what extent they can respond to explicit constraints that might be entailed in various instructions. As a…

Computation and Language · Computer Science 2024-01-02 Yihan Chen , Benfeng Xu , Quan Wang , Yi Liu , Zhendong Mao

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

While Large Language Models (LLMs) have demonstrated exceptional multitasking abilities, fine-tuning these models on downstream, domain-specific datasets is often necessary to yield superior performance on test sets compared to their…

Computation and Language · Computer Science 2024-03-15 Haoran Yang , Yumeng Zhang , Jiaqi Xu , Hongyuan Lu , Pheng Ann Heng , Wai Lam

Instruction tuning is a vital step of training large language models (LLMs), so how to enhance the effect of instruction tuning has received increased attention. Existing works indicate that the quality of the dataset is more crucial than…

Computation and Language · Computer Science 2025-08-27 Bolin Zhang , Jiahao Wang , Qianlong Du , Jiajun Zhang , Zhiying Tu , Dianhui Chu

In education, the capability of generating human-like text of Large Language Models (LLMs) inspired work on how they can increase the efficiency of learning and teaching. We study the affordability of these models for educators and students…

Computation and Language · Computer Science 2025-03-06 Bianca Raimondi , Saverio Giallorenzo , Maurizio Gabbrielli

The current study describes a cost-effective method for adapting large language models (LLMs) for academic advising with study-abroad contexts in mind and for application in low-resource methods for acculturation. With the…

Artificial Intelligence · Computer Science 2025-12-17 Md Millat Hosen
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