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The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Computation and Language · Computer Science 2025-12-19 Xunxin Cai , Chengrui Wang , Qingqing Long , Yuanchun Zhou , Meng Xiao

Large language models (LLMs) have demonstrated strong capabilities across various language tasks, notably through instruction-tuning methods. However, LLMs face challenges in visualizing complex, real-world data through charts and plots.…

Machine Learning · Computer Science 2025-02-18 Fatemeh Pesaran Zadeh , Juyeon Kim , Jin-Hwa Kim , Gunhee Kim

Instruction-based Large Language Models (LLMs) have proven effective in numerous few-shot or zero-shot Natural Language Processing (NLP) tasks. However, creating human-annotated instruction data is time-consuming, expensive, and often…

Computation and Language · Computer Science 2025-05-13 Aniruddha Roy , Pretam Ray , Abhilash Nandy , Somak Aditya , Pawan Goyal

Large Language Models (LLMs) have shown promise in assisting scientific discovery. However, such applications are currently limited by LLMs' deficiencies in understanding intricate scientific concepts, deriving symbolic equations, and…

Computation and Language · Computer Science 2024-11-19 Dan Zhang , Ziniu Hu , Sining Zhoubian , Zhengxiao Du , Kaiyu Yang , Zihan Wang , Yisong Yue , Yuxiao Dong , Jie Tang

In the ongoing wave of impact driven by large language models (LLMs) like ChatGPT, the adaptation of LLMs to medical domain has emerged as a crucial research frontier. Since mainstream LLMs tend to be designed for general-purpose…

Computation and Language · Computer Science 2023-12-04 Issey Sukeda , Masahiro Suzuki , Hiroki Sakaji , Satoshi Kodera

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

Decoder-only LLMs have shown impressive performance in MT due to their ability to learn from extensive datasets and generate high-quality translations. However, LLMs often struggle with the nuances and style required for…

Computation and Language · Computer Science 2024-09-11 Inacio Vieira , Will Allred , Séamus Lankford , Sheila Castilho , Andy Way

Instruction tuning enables language models to more effectively generalize and better follow user intent. However, obtaining instruction data is costly and challenging. Prior work employs methods such as expensive human annotation,…

Computation and Language · Computer Science 2024-10-04 Abdullatif Köksal , Timo Schick , Anna Korhonen , Hinrich Schütze

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

Automated knowledge curation for biomedical ontologies is key to ensure that they remain comprehensive, high-quality and up-to-date. In the era of foundational language models, this study compares and analyzes three NLP paradigms for…

Machine Learning · Computer Science 2023-12-21 Emily Groves , Minhong Wang , Yusuf Abdulle , Holger Kunz , Jason Hoelscher-Obermaier , Ronin Wu , Honghan Wu

Large language models (LLMs) that are tuned with instructions have demonstrated remarkable capabilities in various tasks and languages. However, their ability to generalize to underrepresented languages is limited due to the scarcity of…

Computation and Language · Computer Science 2023-10-25 Samuel Cahyawijaya , Holy Lovenia , Tiezheng Yu , Willy Chung , Pascale Fung

Open-sourced large language models (LLMs) have demonstrated remarkable efficacy in various tasks with instruction tuning. However, these models can sometimes struggle with tasks that require more specialized knowledge such as translation.…

Computation and Language · Computer Science 2024-01-23 Jiali Zeng , Fandong Meng , Yongjing Yin , Jie Zhou

Instruction tuning is now a widely adopted approach to aligning large multimodal models (LMMs) to follow human intent. It unifies the data format of vision-language tasks, enabling multi-task joint training. However, vision-language tasks…

Machine Learning · Computer Science 2023-11-29 Jinghan He , Haiyun Guo , Ming Tang , Jinqiao Wang

Transformer-based language models, though not explicitly trained to mimic brain recordings, have demonstrated surprising alignment with brain activity. Progress in these models-through increased size, instruction-tuning, and…

Instruction tuning is an important step in making language models useful for direct user interaction. However, the legal domain is underrepresented in typical instruction datasets (e.g., only 10 out of 1600+ tasks in…

Pre-trained large language models (LLMs) can be tailored to adhere to human instructions through instruction tuning. However, due to shifts in the distribution of test-time data, they may not always execute instructions accurately,…

Computation and Language · Computer Science 2024-09-04 Hai Ye , Hwee Tou Ng

Despite the advancements of open-source large language models (LLMs), e.g., LLaMA, they remain significantly limited in tool-use capabilities, i.e., using external tools (APIs) to fulfill human instructions. The reason is that current…

The success of ChatGPT has recently attracted numerous efforts to replicate it, with instruction-tuning strategies being a key factor in achieving remarkable results. Instruction-tuning not only significantly enhances the model's…

Computation and Language · Computer Science 2023-03-28 Yunjie Ji , Yong Deng , Yan Gong , Yiping Peng , Qiang Niu , Lei Zhang , Baochang Ma , Xiangang Li

Despite exceptional capabilities, Large Language Models (LLMs) still face deployment challenges due to their enormous size. Post-training structured pruning is a promising solution that prunes LLMs without the need for retraining, reducing…

Machine Learning · Computer Science 2025-02-21 Weizhong Huang , Yuxin Zhang , Xiawu Zheng , Fei Chao , Rongrong Ji

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by…

Machine Learning · Computer Science 2026-04-16 Jiahao Shao , Anam Nawaz Khan , Christopher Brett , Tom Berg , Xueping Li , Bing Yao