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A method that reconstructs protein residue networks using suitable node selection and edge recovery policies produced numerical observations that correlate strongly (Pearson's correlation coefficient < -0.83) with published folding rates…

Biomolecules · Quantitative Biology 2026-04-07 Susan Khor

While modern structural biology has provided us with a rich and diverse picture of membrane proteins, the biological function of membrane proteins is often influenced by the mechanical properties of the surrounding lipid bilayer. Here we…

Biomolecules · Quantitative Biology 2013-05-27 Christoph A. Haselwandter , Rob Phillips

The prediction of the three-dimensional structures of the native state of proteins from the sequences of their amino acids is one of the most important challenges in molecular biology. An essential ingredient to solve this problem within…

Statistical Mechanics · Physics 2007-05-23 Cristian Micheletti , Flavio Seno , Jayanth Banavar , Amos Maritan

Recent developments in nanotechnology herald nanometer-sized devices expected to bring light to a number of groundbreaking applications. Communication with and among nanodevices will be needed for unlocking the full potential of such…

Networking and Internet Architecture · Computer Science 2021-02-08 Filip Lemic , Sergi Abadal , Wouter Tavernier , Pieter Stroobant , Didier Colle , Eduard Alarcón , Johann Marquez-Barja , Jeroen Famaey

Ultrafast optical excitations trigger in materials a range of dynamics. An interesting range of dynamics is the ones that unfold within the picosecond timescale, corresponding to the THz frequency range. Within this short timescale, the…

Optics · Physics 2023-09-27 Yingshu Yang , Stefano Dal Forno , Marco Battiato

The transition frequency between nonthermal coherent magnetic precessions and ultrafast demagnetization is arguably the most sought after answer in magnetism science and technology nowadays. So far, it is believed to be in the terahertz…

Optics · Physics 2015-06-18 Mostafa Shalaby , Carlo Vicario , Christoph P. Hauri

The primary structure of proteins, that is their sequence, represents one of the most abundant set of experimental data concerning biomolecules. The study of correlations in families of co--evolving proteins by means of an inverse…

Biomolecules · Quantitative Biology 2015-06-16 Sara Lui , Guido Tiana

Communication at terahertz (THz) frequency bands is a promising solution for achieving extremely high data rates in next-generation wireless networks. While the THz communication is conventionally envisioned for short-range wireless…

Information Theory · Computer Science 2021-02-11 Arian Ahmadi , Omid Semiari

The analysis of correlations of amino acid occurrences in globular proteins has led to the development of statistical tools that can identify native contacts -- portions of the chains that come to close distance in folded structural…

Biomolecules · Quantitative Biology 2014-07-28 Rocío Espada , R. Gonzalo Parra , Thierry Mora , Aleksandra M. Walczak , Diego Ferreiro

Hydration water is vital for the stabilization of protein structure and function. The strong interaction of hydration water with the protein surface brings into question how dynamics and asymmetry of hydrogen bonds are perturbed for…

We theoretically investigate the steady-state transmission of continuous terahertz (THz) wave across a freestanding ferroelectric slab. Based on the Landau-Ginzburg-Devonshire theory of ferroelectrics and the coupled equations of motion for…

Mesoscale and Nanoscale Physics · Physics 2024-08-07 Taorui Chen , Bo Wang , Yujie Zhu , Shihao Zhuang , Long-Qing Chen , Jia-Mian Hu

Natural proteins fold to a unique, thermodynamically dominant state. Modeling of the folding process and prediction of the native fold of proteins are two major unsolved problems in biophysics. Here, we show successful all-atom ab initio…

Biomolecules · Quantitative Biology 2007-05-23 Jae Shick Yang , William W. Chen , Jeffrey Skolnick , Eugene I. Shakhnovich

The spatio-temporal organization of proteins and the associated morphological changes in membranes are of importance in cell signaling. Several mechanisms that promote the aggregation of proteins at low cell surface concentrations have been…

Biological Physics · Physics 2018-04-18 K. K. Sreeja , P. B. Sunil Kumar

Mitigating channel fading and transceiver impairments are desirable for high-speed terahertz (THz) wireless links. This paper analyzes the performance of a multi-antenna THz wireless system by considering the combined effect of pointing…

Information Theory · Computer Science 2021-08-05 Atharva Anand Joshi , Pranay Bhardwaj , S. M. Zafaruddin

Focusing on a small set of proteins that i) fold in a concerted, all-or-none fashion and ii) do not contain knots or slipknots, we show that the Gauss linking integral, the torsion and the number of sequence-distant contacts provide…

Quantitative Methods · Quantitative Biology 2019-10-01 E. Panagiotou , K. W. Plaxco

The control of biopolymer length is mediated by proteins that localize to polymer ends and regulate polymerization dynamics. Several mechanisms have been proposed to achieve end localization. Here, we propose a novel mechanism by which a…

Biological Physics · Physics 2026-03-12 Amer Al-Hiyasat , Yazgan Tuna , Yin-Wei Kuo , Jonathon Howard

We consider the influence of a terahertz field on the breathing dynamics of double-stranded DNA. We model the spontaneous formation of spatially localized openings of a damped and driven DNA chain, and find that linear instabilities lead to…

Biological Physics · Physics 2010-01-27 B. S. Alexandrov , V. Gelev , A. R. Bishop , A. Usheva , K. O. Rasmussen

Motivation: Protein folding is a dynamic process during which a protein's amino acid sequence undergoes a series of 3-dimensional (3D) conformational changes en route to reaching a native 3D structure; the resulting 3D structural…

Biomolecules · Quantitative Biology 2026-04-09 Aydin Wells , Khalique Newaz , Jennifer Morones , Jianlin Cheng , Tijana Milenković

The self-organization of proteins into enriched compartments and the formation of complex patterns are crucial processes for life on the cellular level. Liquid-liquid phase separation is one mechanism for forming such enriched compartments.…

Soft Condensed Matter · Physics 2025-04-07 Antonia Winter , Yuhao Liu , Alexander Ziepke , George Dadunashvili , Erwin Frey

Proteins are the "work horses" in biological systems. In almost all functions specific proteins are involved. They control molecular transport processes, stabilize the cell structure, enzymatically catalyze chemical reactions; others act as…

Statistical Mechanics · Physics 2009-02-18 Michael Bachmann , Wolfhard Janke