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Much of the complexity observed in gene regulation originates from cooperative protein-DNA binding. While studies of the target search of proteins for their specific binding sites on the DNA have revealed design principles for the…

Biomolecules · Quantitative Biology 2015-05-30 Nico Geisel , Ulrich Gerland

Strong optical pulses at mid-infrared and terahertz frequencies have recently emerged as a powerful tool to manipulate and control the solid state and especially complex condensed matter systems with strongly correlated electrons. The…

Strongly Correlated Electrons · Physics 2016-08-22 Daniele Nicoletti , Andrea Cavalleri

Controlling light polarization is one of the most essential routines in modern optical technology. Since the demonstration of optical pulse shaping by spatial light modulators and its potential in controlling the quantum reaction pathways,…

With the recent developments on opening the terahertz (THz) spectrum for experimental purposes by the Federal Communications Commission, transceivers operating in the range of 0.1THz-10THz, which are known as THz bands, will enable…

Signal Processing · Electrical Eng. & Systems 2021-03-02 Kürşat Tekbıyık , Ali Rıza Ekti , Güneş Karabulut Kurt , Ali Görçin , Serhan Yarkan

Tunable bandpass terahertz filters are demanded in various key applications such as hyperspectral imagers, miniaturized spectrometers, and high-speed wireless communication systems. Here, a mechanically reconfigurable double-layered…

Optics · Physics 2026-04-20 Sanaz Zarei

A model to describe the mechanism of conformational dynamics in protein based on matter interactions using lagrangian approach and imposing certain symmetry breaking is proposed. Both conformation changes of proteins and the injected…

Biological Physics · Physics 2015-03-13 M. Januar , A. Sulaiman , L. T. Handoko

The prediction of the three-dimensional native structure of proteins from the knowledge of their amino acid sequence, known as the protein folding problem, is one of the most important yet unsolved issues of modern science. Since the…

Biological Physics · Physics 2008-11-24 Pablo Echenique

Availability of high-resolution crystal structures of ribosomal subunits of different species opens a route to investigate about molecular interactions between its constituents and stabilization strategy. Structural analysis of the small…

Biomolecules · Quantitative Biology 2012-12-06 Saurav Mallik , Sudip Kundu

Although both RNA and proteins have densely packed native structures, chain organizations of these two biopolymers are fundamentally different. Motivated by the recent discoveries in chromatin folding that interphase chromosomes have…

Soft Condensed Matter · Physics 2016-12-28 Lei Liu , Changbong Hyeon

Using tools from stochastic geometry, this paper develops a tractable framework to analyze the performance of a mobile user in a two-tier wireless network operating on sub-6GHz and terahertz (THz) transmission frequencies. Specifically,…

Information Theory · Computer Science 2021-12-21 Md Tanvir Hossan , Hina Tabassum

Protein-protein bindings play a key role in a variety of fundamental biological processes, and thus predicting the effects of amino acid mutations on protein-protein binding is crucial. To tackle the scarcity of annotated mutation data,…

Quantitative Methods · Quantitative Biology 2024-05-20 Lirong Wu , Yijun Tian , Haitao Lin , Yufei Huang , Siyuan Li , Nitesh V Chawla , Stan Z. Li

We use a free energy functional theory to elucidate general properties of heterogeneously ordering, fast folding proteins, and we test our conclusions with lattice simulations. We find that both structural and energetic heterogeneity can…

Disordered Systems and Neural Networks · Physics 2009-10-31 Steven S. Plotkin , Jose N. Onuchic

We numerically analyse extraordinary terahertz transmission properties of an array of rectangular shaped apertures perforated periodically on a thin metal film. The apertures are tapered at different angles to achieve higher field…

Optics · Physics 2016-03-01 Koijam Monika Devi , Amarendra K. Sarma , Gagan Kumar

Terahertz (THz) communication is widely considered as a key enabler for future 6G wireless systems. However, THz links are subject to high propagation losses and inter-symbol interference due to the frequency selectivity of the channel.…

Information Theory · Computer Science 2021-02-16 Konstantinos Dovelos , Michail Matthaiou , Hien Quoc Ngo , Boris Bellalta

We experimentally study the effect of near field coupling on the transmission of light in terahertz metasurfaces, possessing slightly distinctive SRR resonances. Our results show that the interplay between the strengths of electric and…

The three dimensional structure of a protein is an outcome of the interactions of its constituent amino acids in 3D space. Considering the amino acids as nodes and the interactions among them as edges we have constructed and analyzed…

Biomolecules · Quantitative Biology 2010-07-26 Dhriti Sengupta , Sudip Kundu

Electrostatic interactions involving proteins depend not just on the ionic charges involved but also on their chemical identities. Here we examine the origins of incompletely understood differences in the strength of association of…

Chemical Physics · Physics 2023-08-15 Chase E. Herman , Arjun Valiya Parambathu , D. N. Asthagiri , Abraham M. Lenhoff

We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first order phase transition, cooperativity and is exactly solvable. It also…

Condensed Matter · Physics 2015-06-25 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters…

Molecular Networks · Quantitative Biology 2014-08-12 Gabriele Scheler

Terahertz (THz) communication is a promising technology for future wireless communications, offering data rates of up to several terabits-per-second (Tbps). However, the range of THz band communications is often limited by high pathloss and…

Signal Processing · Electrical Eng. & Systems 2024-01-29 Muddasir Rahim , Thanh Luan Nguyen , Georges Kaddoum , Tri Nhu Do
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