English

A hierarchical scheme for cooperativity and folding in proteins

Condensed Matter 2015-06-25 v3 chao-dyn Chaotic Dynamics q-bio

Abstract

We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first order phase transition, cooperativity and is exactly solvable. It also shows an unexpected symmetry between folding and unfolding pathways as suggested by a recent experiment.

Keywords

Cite

@article{arxiv.cond-mat/9701075,
  title  = {A hierarchical scheme for cooperativity and folding in proteins},
  author = {Alex Hansen and Mogens H. Jensen and Kim Sneppen and Giovanni Zocchi},
  journal= {arXiv preprint arXiv:cond-mat/9701075},
  year   = {2015}
}

Comments

4 pages RevTeX, 4 Postscript figures. Contents substantially revised compared to previous version