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The advancement of Large Language Models (LLMs) for domain applications in fields such as materials science and engineering depends on the development of fine-tuning strategies that adapt models for specialized, technical capabilities. In…

Computation and Language · Computer Science 2024-09-06 Wei Lu , Rachel K. Luu , Markus J. Buehler

With the rapid advancement of Large Language Models (LLMs), the Chain-of-Thought (CoT) component has become significant for complex reasoning tasks. However, in conventional Supervised Fine-Tuning (SFT), the model could allocate…

Computation and Language · Computer Science 2025-12-25 Xiaofeng Shi , Qian Kou , Yuduo Li , Hua Zhou

In this paper, we present HuatuoGPT, a large language model (LLM) for medical consultation. The core recipe of HuatuoGPT is to leverage both \textit{distilled data from ChatGPT} and \textit{real-world data from doctors} in the supervised…

Computation and Language · Computer Science 2023-05-25 Hongbo Zhang , Junying Chen , Feng Jiang , Fei Yu , Zhihong Chen , Jianquan Li , Guiming Chen , Xiangbo Wu , Zhiyi Zhang , Qingying Xiao , Xiang Wan , Benyou Wang , Haizhou Li

Large Language Models (LLMs) show potential for medical applications but often lack specialized clinical knowledge. Retrieval Augmented Generation (RAG) allows customization with domain-specific information, making it suitable for…

In the information and communications technology (ICT) industry, training a domain-specific large language model (LLM) or constructing a retrieval-augmented generation system requires a substantial amount of high-value domain knowledge.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Lianying Chao , Kai Zhang , Haoran Cai , Sijie Wu , Xubin Li , Xin Chen

To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Computation and Language · Computer Science 2026-04-21 Yuxin Xiao , Shujian Zhang , Wenxuan Zhou , Marzyeh Ghassemi , Sanqiang Zhao

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Multi-modal large language models(MLLMs) have achieved remarkable progress and demonstrated powerful knowledge comprehension and reasoning abilities. However, the mastery of domain-specific knowledge, which is essential for evaluating the…

Computation and Language · Computer Science 2024-05-09 Zheqi He , Xinya Wu , Pengfei Zhou , Richeng Xuan , Guang Liu , Xi Yang , Qiannan Zhu , Hua Huang

General-purpose Large Language Models (LLMs) are frequently fine-tuned through supervised fine-tuning (SFT) to enhance performance in specific domains. Better results can be achieved by distilling the chain-of-thought of a larger model at…

Machine Learning · Computer Science 2026-03-24 Andrey Goncharov , Daniil Vyazhev , Petr Sychev , Edvard Khalafyan , Alexey Zaytsev

Large Language Models (LLMs) have shown remarkable progress in medical question answering (QA), yet their effectiveness remains predominantly limited to English due to imbalanced multilingual training data and scarce medical resources for…

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Recent advances in reasoning-enhanced Large Language Models such as OpenAI-o1/3 and DeepSeek-R1 have significantly improved performance on complex tasks. However, the quality and transparency of their internal reasoning processes remain…

Computation and Language · Computer Science 2025-06-04 Juncheng Wu , Sheng Liu , Haoqin Tu , Hang Yu , Xiaoke Huang , James Zou , Cihang Xie , Yuyin Zhou

Traditional Chinese Medicine (TCM) presents a rich and structurally unique knowledge system that challenges conventional applications of large language models (LLMs). Although previous TCM-specific LLMs have shown progress through…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Shuai Zeng , Yang Yu , Xiaoting Tang , Guanghui An , Dong Xu

Supervised fine-tuning (SFT) is a critical step in aligning large language models (LLMs) with human instructions and values, yet many aspects of SFT remain poorly understood. We trained a wide range of base models on a variety of datasets…

Computation and Language · Computer Science 2025-10-31 Yuto Harada , Yusuke Yamauchi , Yusuke Oda , Yohei Oseki , Yusuke Miyao , Yu Takagi

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

Computation and Language · Computer Science 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

Large Language Models (LLMs) provide a possibility to make a great breakthrough in medicine. The establishment of a standardized medical benchmark becomes a fundamental cornerstone to measure progression. However, medical environments in…

Computation and Language · Computer Science 2024-04-05 Xidong Wang , Guiming Hardy Chen , Dingjie Song , Zhiyi Zhang , Zhihong Chen , Qingying Xiao , Feng Jiang , Jianquan Li , Xiang Wan , Benyou Wang , Haizhou Li