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Relationship inference from sparse data is an important task with applications ranging from product recommendation to drug discovery. A recently proposed linear model for sparse matrix completion has demonstrated surprising advantage in…
Medication Recommendation (MR) is a promising research topic which booms diverse applications in the healthcare and clinical domains. However, existing methods mainly rely on sequential modeling and static graphs for representation…
Estimating mutual correlations between random variables or data streams is essential for intelligent behavior and decision-making. As a fundamental quantity for measuring statistical relationships, mutual information has been extensively…
The problem of data sparsity has long been a challenge in recommendation systems, and previous studies have attempted to address this issue by incorporating side information. However, this approach often introduces side effects such as…
To increase statistical efficiency in a randomized experiment, researchers often use stratification (i.e., blocking) in the design stage. However, conventional practices of stratification fail to exploit valuable information about the…
The rise of In-Context Learning (ICL) for universal medical image segmentation has introduced an unprecedented demand for large-scale, diverse datasets for training, exacerbating the long-standing problem of data scarcity. While data…
In biomedical research, to obtain more accurate prediction results from a target study, leveraging information from multiple similar source studies is proved to be useful. However, in many biomedical applications based on real-world data,…
Training deep learning models on medical datasets that perform well for all classes is a challenging task. It is often the case that a suboptimal performance is obtained on some classes due to the natural class imbalance issue that comes…
Long-tailed class distributions are pervasive in multi-class medical datasets and pose significant challenges for deep learning models which typically underperform on tail classes with limited samples. This limitation is particularly…
Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…
Collaborative learning, which enables collaborative and decentralized training of deep neural networks at multiple institutions in a privacy-preserving manner, is rapidly emerging as a valuable technique in healthcare applications. However,…
Recent years witnessed remarkable progress in computational histopathology, largely fueled by deep learning. This brought the clinical adoption of deep learning-based tools within reach, promising significant benefits to healthcare,…
In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…
Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…
Motivated by distributed machine learning settings such as Federated Learning, we consider the problem of fitting a statistical model across a distributed collection of heterogeneous data sets whose similarity structure is encoded by a…
While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…
With the increasing multimedia information, multimodal recommendation has received extensive attention. It utilizes multimodal information to alleviate the data sparsity problem in recommendation systems, thus improving recommendation…
In Elmarakeby et al., "Biologically informed deep neural network for prostate cancer discovery", a feedforward neural network with biologically informed, sparse connections (P-NET) was presented to model the state of prostate cancer. We…
Medical image classification has been widely adopted in medical image analysis. However, due to the difficulty of collecting and labeling data in the medical area, medical image datasets are usually highly-imbalanced. To address this…
Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…