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Machine learning strategies like multi-task learning, meta-learning, and transfer learning enable efficient adaptation of machine learning models to specific applications in healthcare, such as prediction of various diseases, by leveraging…

Machine Learning · Computer Science 2024-12-31 Sophie Wharrie , Lisa Eick , Lotta Mäkinen , Andrea Ganna , Samuel Kaski , FinnGen

Randomized clinical trials are often designed to assess whether a test treatment prolongs survival relative to a control treatment. Increased patient heterogeneity, while desirable for generalizability of results, can weaken the ability of…

Methodology · Statistics 2020-04-30 Devan V. Mehrotra , Rachel Marceau West

This paper studies a two-stage model of experimentation, where the researcher first samples representative units from an eligible pool, then assigns each sampled unit to treatment or control. To implement balanced sampling and assignment,…

Econometrics · Economics 2023-08-22 Max Cytrynbaum

While sparse attention mitigates the computational bottleneck of long-context LLM training, its distributed training process exhibits extreme heterogeneity in both \textit{1)} sequence length and \textit{2)} sparsity sensitivity, leading to…

Machine Learning · Computer Science 2026-04-27 Hongtao Xu , Jianchao Tan , Yuxuan Hu , Pengju Lu , Hongyu Wang , Pingwei Sun , Yerui Sun , Yuchen Xie , Xunliang Cai , Mingzhen Li , Weile Jia

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

Computation and Language · Computer Science 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

Estimating individualized treatment effects from longitudinal observational data is central to data-driven medicine, yet existing methods face a fundamental limitation: reducing confounding bias often suppresses clinically informative…

Rare diseases dominate the diagnostic challenge in medical imaging yet are severely underrepresented in clinical datasets, causing classifiers to fail on exactly the conditions where reliable detection matters most. Generative augmentation…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Felix Nützel , Mischa Dombrowski , Bernhard Kainz

Scribble-supervised medical image segmentation tackles the limitation of sparse masks. Conventional approaches alternate between: labeling pseudo-masks and optimizing network parameters. However, such iterative two-stage paradigm is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zefan Yang , Di Lin , Dong Ni , Yi Wang

Deep learning approaches exhibit promising performances on various text tasks. However, they are still struggling on medical text classification since samples are often extremely imbalanced and scarce. Different from existing mainstream…

Computation and Language · Computer Science 2023-11-29 Jiahuan Yan , Haojun Gao , Zhang Kai , Weize Liu , Danny Chen , Jian Wu , Jintai Chen

Medical image segmentation typically necessitates a large and precisely annotated dataset. However, obtaining pixel-wise annotation is a labor-intensive task that requires significant effort from domain experts, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Heng Cai , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

The management of chronic Heart Failure (HF) presents significant challenges in modern healthcare, requiring continuous monitoring, early detection of exacerbations, and personalized treatment strategies. In this paper, we present a…

Synthetic healthcare data generation presents a viable approach to enhance data accessibility and support research by overcoming limitations associated with real-world medical datasets. However, ensuring fairness across protected attributes…

Machine Learning · Computer Science 2025-11-04 Sama Salarian , Yue Zhang , Swati Padhee , Srinivasan Parthasarathy

A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug…

Medication recommendation is crucial in healthcare, offering effective treatments based on patient's electronic health records (EHR). Previous studies show that integrating more medication-related knowledge improves medication…

Artificial Intelligence · Computer Science 2025-04-28 Xiang Li , Haixu Ma , Guanyong Wu , Shi Mu , Chen Li , Shunpan Liang

Clinical trials are notorious for their high failure rates and steep costs, leading to wasted time and resources spend, prolonged development timelines, and delayed patient access to new therapies. A key contributor to these failures is…

Quantum Physics · Physics 2026-01-19 Laia Domingo , Christine Johnson

With the rapid growth of digital information, personalized recommendation systems have become an indispensable part of Internet services, especially in the fields of e-commerce, social media, and online entertainment. However, traditional…

Information Retrieval · Computer Science 2024-11-12 Yuanshuai Luo , Rui Wang , Yaxin Liang , Ankai Liang , Wenyi Liu

The limited representation of minorities and disadvantaged populations in large-scale clinical and genomics research has become a barrier to translating precision medicine research into practice. Due to heterogeneity across populations,…

Machine Learning · Statistics 2021-08-30 Sai Li , Tianxi Cai , Rui Duan

The classification of clinical notes into specific diagnostic categories is critical in healthcare, especially for mental health conditions like Anxiety and Adjustment Disorder. In this study, we compare the performance of various…

Complex multi-robot missions often require heterogeneous teams to jointly optimize task allocation, scheduling, and path planning to improve team performance under strict constraints. We formalize these complexities into a new class of…

Robotics · Computer Science 2026-01-07 Jiazhen Liu , Glen Neville , Jinwoo Park , Sonia Chernova , Harish Ravichandar

Propensity score weighting approaches have been widely implemented in clinical research to estimate the effects of a treatment or exposure while mitigating the risk of confounding in the absence of random assignment. In practice, when…

Methodology · Statistics 2026-04-17 Emma K. Mackay , Amol A. Verma , Fahad Razak , Surain B. Roberts