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In the field of medical image analysis, deep learning models have demonstrated remarkable success in enhancing diagnostic accuracy and efficiency. However, the reliability of these models is heavily dependent on the quality of training…
Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…
This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…
Human coders assign standardized medical codes to clinical documents generated during patients' hospitalization, which is error-prone and labor-intensive. Automated medical coding approaches have been developed using machine learning…
Generative Recommendation (GR) has recently transitioned from atomic item-indexing to Semantic ID (SID)-based frameworks to capture intrinsic item relationships and enhance generalization. However, the adoption of high-granularity SIDs…
A widely used paradigm to improve the generalization performance of high-capacity neural models is through the addition of auxiliary unsupervised tasks during supervised training. Tasks such as similarity matching and input reconstruction…
Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…
Harmonizing the analysis of data, especially of 3-D image volumes, consisting of different number of slices and annotated per volume, is a significant problem in training and using deep neural networks in various applications, including…
We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…
Despite the superior performance of Deep Learning (DL) on numerous segmentation tasks, the DL-based approaches are notoriously overconfident about their prediction with highly polarized label probability. This is often not desirable for…
Segmentation of thigh tissues (muscle, fat, inter-muscular adipose tissue (IMAT), bone, and bone marrow) from magnetic resonance imaging (MRI) scans is useful for clinical and research investigations in various conditions such as aging,…
This Perspective provides examples of current and future applications of deep learning in pharmacogenomics, including: (1) identification of novel regulatory variants located in noncoding domains and their function as applied to…
In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…
Recently, deep models have been successfully applied in several applications, especially with low-level representations. However, sparse, noisy samples and structured domains (with multiple objects and interactions) are some of the open…
In machine learning larger databases are usually associated with higher classification accuracy due to better generalization. This generalization may lead to non-optimal classifiers in some medical applications with highly variable…
Real-life medical data is often multimodal and incomplete, fueling the growing need for advanced deep learning models capable of integrating them efficiently. The use of diverse modalities, including histopathology slides, MRI, and genetic…
The growing prevalence and complexity of mental health disorders present significant challenges for accurate diagnosis and treatment, particularly in understanding the interplay between co-occurring conditions. Mental health disorders, such…
The performance of learning-based algorithms improves with the amount of labelled data used for training. Yet, manually annotating data is particularly difficult for medical image segmentation tasks because of the limited expert…
Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…
Interactive medical questioning is essential in real-world clinical consultations, where physicians must actively gather information from patients. While medical Large Language Models (LLMs) have shown impressive capabilities in static…