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Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

Depression remains a pressing global mental health issue, driving considerable research into AI-driven detection approaches. While pre-trained models, particularly speech self-supervised models (SSL Models), have been applied to depression…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-11 Xiangyu Zhang , Beena Ahmed , Julien Epps

This study explores the use of Large Language Models (LLMs) to analyze text comments from Reddit users, aiming to achieve two primary objectives: firstly, to pinpoint critical excerpts that support a predefined psychological assessment of…

Computation and Language · Computer Science 2024-02-07 Sergi Blanco-Cuaresma

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Understanding the conversation abilities of Large Language Models (LLMs) can help lead to its more cautious and appropriate deployment. This is especially important for safety-critical domains like mental health, where someone's life may…

Computation and Language · Computer Science 2024-03-18 Alexander Marrapese , Basem Suleiman , Imdad Ullah , Juno Kim

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Large Language Models (LLMs) have demonstrated remarkable performance across various information-seeking and reasoning tasks. These computational systems drive state-of-the-art dialogue systems, such as ChatGPT and Bard. They also carry…

Computation and Language · Computer Science 2023-10-13 Siyuan Brandon Loh , Aravind Sesagiri Raamkumar

Recent research has focused on examining Large Language Models' (LLMs) characteristics from a psychological standpoint, acknowledging the necessity of understanding their behavioral characteristics. The administration of personality tests…

Computation and Language · Computer Science 2024-10-07 Jen-tse Huang , Wenxiang Jiao , Man Ho Lam , Eric John Li , Wenxuan Wang , Michael R. Lyu

Mental health disorders represent a burgeoning global public health challenge. While Large Language Models (LLMs) have demonstrated potential in psychiatric assessment, their clinical utility is severely constrained by benchmarks that lack…

Artificial Intelligence · Computer Science 2026-02-04 Xiao Sun , Yuming Yang , Junnan Zhu , Jiang Zhong , Xinyu Zhou , Kaiwen Wei

There is a significant gap between patient needs and available mental health support today. In this paper, we aim to thoroughly examine the potential of using Large Language Models (LLMs) to assist professional psychotherapy. To this end,…

Computation and Language · Computer Science 2025-01-28 Mian Zhang , Xianjun Yang , Xinlu Zhang , Travis Labrum , Jamie C. Chiu , Shaun M. Eack , Fei Fang , William Yang Wang , Zhiyu Zoey Chen

In recent years, large language models (LLMs) have been extensively utilized for behavioral modeling, for example, to automatically generate sequence diagrams. However, no overview of this work has been published yet. Such an overview will…

Software Engineering · Computer Science 2025-09-30 Muhammad Laiq

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

Large language models (LLMs) are increasingly explored for clinical decision support, yet most evaluations are conducted in English, leaving their reliability in other languages uncertain. Here we evaluate the impact of prompting language…

Computation and Language · Computer Science 2026-05-20 Adrien Bazoge , Josselin Corvellec , Sofiane Djillali Sid-Ahmed , Pierre-Antoine Gourraud

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which has heightened the need for timely and professional mental health support. Online psychological…

Computation and Language · Computer Science 2023-09-04 Tin Lai , Yukun Shi , Zicong Du , Jiajie Wu , Ken Fu , Yichao Dou , Ziqi Wang

This study investigates the linguistic understanding of Large Language Models (LLMs) regarding signifier (form) and signified (meaning) by distinguishing two LLM assessment paradigms: psycholinguistic and neurolinguistic. Traditional…

Computation and Language · Computer Science 2025-07-15 Linyang He , Ercong Nie , Helmut Schmid , Hinrich Schütze , Nima Mesgarani , Jonathan Brennan

Timely identification is essential for the efficient handling of mental health illnesses such as depression. However, the current research fails to adequately address the prediction of mental health conditions from social media data in…

Computation and Language · Computer Science 2024-04-16 Zita Lifelo , Huansheng Ning , Sahraoui Dhelim

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Evaluating Large Language Models (LLMs) in the mental health domain poses distinct challenged from other domains, given the subtle and highly subjective nature of symptoms that exhibit significant variability among individuals. This paper…

Computation and Language · Computer Science 2024-06-04 Haoan Jin , Siyuan Chen , Dilawaier Dilixiati , Yewei Jiang , Mengyue Wu , Kenny Q. Zhu

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Computation and Language · Computer Science 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo
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