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We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

Computation and Language · Computer Science 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Despite the recent successes of large, pretrained neural language models (LLMs), comparatively little is known about the representations of linguistic structure they learn during pretraining, which can lead to unexpected behaviors in…

Computation and Language · Computer Science 2024-12-24 Adam Davies , Jize Jiang , ChengXiang Zhai

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

We investigate the predictability of large language model (LLM) capabilities: given records of past experiments using different model families, numbers of parameters, tasks, and numbers of in-context examples, can we accurately predict LLM…

Computation and Language · Computer Science 2023-11-01 Qinyuan Ye , Harvey Yiyun Fu , Xiang Ren , Robin Jia

Large language models (LLMs) show promise for improving the efficiency of qualitative analysis in large, multi-site health-services research. Yet methodological guidance for LLM integration into qualitative analysis and evidence of their…

Computation and Language · Computer Science 2026-01-22 Sasha Ronaghi , Emma-Louise Aveling , Maria Levis , Rachel Lauren Ross , Emily Alsentzer , Sara Singer

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

In contemporary society, the issue of psychological health has become increasingly prominent, characterized by the diversification, complexity, and universality of mental disorders. Cognitive Behavioral Therapy (CBT), currently the most…

Computation and Language · Computer Science 2024-07-26 Hao Shen , Zihan Li , Minqiang Yang , Minghui Ni , Yongfeng Tao , Zhengyang Yu , Weihao Zheng , Chen Xu , Bin Hu

Mental health has become a global priority, leading to a massive administrative burden in the coding of clinical diagnoses. This study proposes the automation of psychiatric diagnostic analysis by mapping free-text descriptions to the…

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come…

Computation and Language · Computer Science 2024-08-02 Hannah R. Lawrence , Renee A. Schneider , Susan B. Rubin , Maja J. Mataric , Daniel J. McDuff , Megan Jones Bell

Large Language Models (LLMs), originally developed for natural language processing (NLP), have demonstrated the potential to generalize across modalities and domains. With their in-context learning (ICL) capabilities, LLMs can perform…

Artificial Intelligence · Computer Science 2025-08-26 Nikolaos Pavlidis , Vasilis Perifanis , Symeon Symeonidis , Pavlos S. Efraimidis

What makes large language models (LLMs) impressive is also what makes them hard to evaluate: their diversity of uses. To evaluate these models, we must understand the purposes they will be used for. We consider a setting where these…

Computation and Language · Computer Science 2024-06-04 Keyon Vafa , Ashesh Rambachan , Sendhil Mullainathan

Disorganized thinking is a key diagnostic indicator of schizophrenia-spectrum disorders. Recently, clinical estimates of the severity of disorganized thinking have been shown to correlate with measures of how difficult speech transcripts…

Computation and Language · Computer Science 2025-03-27 Changye Li , Weizhe Xu , Serguei Pakhomov , Ellen Bradley , Dror Ben-Zeev , Trevor Cohen

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and…

Although explainability and interpretability have received significant attention in artificial intelligence (AI) and natural language processing (NLP) for mental health, reasoning has not been examined in the same depth. Addressing this gap…

Computation and Language · Computer Science 2025-11-10 Sneha Oram , Pushpak Bhattacharyya

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Large Language Models (LLMs) have demonstrated remarkable capabilities in reasoning and generation, serving as the foundation for advanced persona simulation and Role-Playing Language Agents (RPLAs). However, achieving authentic alignment…

Computation and Language · Computer Science 2026-04-20 Xintao Wang , Jian Yang , Weiyuan Li , Rui Xie , Jen-tse Huang , Jun Gao , Shuai Huang , Yueping Kang , Yuanli Gou , Hongwei Feng , Yanghua Xiao

Large Language Models (LLMs) achieve impressive performance in a wide range of tasks, even if they are often trained with the only objective of chatting fluently with users. Among other skills, LLMs show emergent abilities in mathematical…

Computation and Language · Computer Science 2024-06-12 Flavio Petruzzellis , Alberto Testolin , Alessandro Sperduti

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

The rapid evolution of Large Language Models (LLMs) presents a promising solution to the global shortage of mental health professionals. However, their alignment with essential counseling competencies remains underexplored. We introduce…

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