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Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed…

Machine Learning · Computer Science 2025-09-03 Abu Shad Ahammed , Sayeri Mukherjee , Roman Obermaisser

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

As demand for mental health care outpaces clinician-delivered assessment, scalable screening tools are increasingly needed. Large language models (LLMs) may identify psychiatric risk from patient narratives, but their reliability across…

Computation and Language · Computer Science 2026-05-26 Jianfeng Zhu , Megan Korhummel , Ruoming Jin , Karin G. Coifman

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

This paper compares the effectiveness of traditional machine learning methods, encoder-based models, and large language models (LLMs) on the task of detecting depression and anxiety. Five Russian-language datasets were considered, each…

Computation and Language · Computer Science 2025-11-04 Gleb Kuzmin , Petr Strepetov , Maksim Stankevich , Natalia Chudova , Artem Shelmanov , Ivan Smirnov

Large Language Models (LLMs) have remarkable capabilities across NLP tasks. However, their performance in multilingual contexts, especially within the mental health domain, has not been thoroughly explored. In this paper, we evaluate…

Computation and Language · Computer Science 2026-02-03 Nishat Raihan , Sadiya Sayara Chowdhury Puspo , Ana-Maria Bucur , Stevie Chancellor , Marcos Zampieri

Advances in large language models (LLMs) have empowered a variety of applications. However, there is still a significant gap in research when it comes to understanding and enhancing the capabilities of LLMs in the field of mental health. In…

Computation and Language · Computer Science 2024-01-30 Xuhai Xu , Bingsheng Yao , Yuanzhe Dong , Saadia Gabriel , Hong Yu , James Hendler , Marzyeh Ghassemi , Anind K. Dey , Dakuo Wang

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

The advent of Large Language Models (LLMs) offers potential solutions to address problems such as shortage of medical resources and low diagnostic consistency in psychiatric clinical practice. Despite this potential, a robust and…

Computation and Language · Computer Science 2025-06-19 Shuyu Liu , Ruoxi Wang , Ling Zhang , Xuequan Zhu , Rui Yang , Xinzhu Zhou , Fei Wu , Zhi Yang , Cheng Jin , Gang Wang

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

Patients who are at clinical high risk (CHR) for schizophrenia need close monitoring of their symptoms to inform appropriate treatments. The Brief Psychiatric Rating Scale (BPRS) is a validated, commonly used research tool for measuring…

Computation and Language · Computer Science 2025-08-15 Andrew X. Chen , Guillermo Horga , Sean Escola

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria

Large language models (LLMs) have attracted growing interest as supportive tools for psychiatric assessment and clinical decision support. However, existing mental health benchmarks largely rely on social media data or supportive dialogue…

Computation and Language · Computer Science 2026-05-19 Hoyun Song , Migyeong Kang , Jisu Shin , Jihyun Kim , Chanbi Park , Hangyeol Yoo , Jihyun An , Alice Oh , Jinyoung Han , KyungTae Lim

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim
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