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Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Large Language Models (LLMs) are increasingly used for mental health support, yet little is known about how people with mental health challenges engage with them, how they evaluate their usefulness, and what design opportunities they…

Human-Computer Interaction · Computer Science 2026-02-12 Aditya Kumar Purohit , Hendrik Heuer

Psychological support hotlines serve as critical lifelines for crisis intervention but encounter significant challenges due to rising demand and limited resources. Large language models (LLMs) offer potential support in crisis assessments,…

Computation and Language · Computer Science 2025-12-19 Guifeng Deng , Shuyin Rao , Tianyu Lin , Anlu Dai , Pan Wang , Junyi Xie , Haidong Song , Ke Zhao , Dongwu Xu , Zhengdong Cheng , Tao Li , Haiteng Jiang

Mental health challenges pose considerable global burdens on individuals and communities. Recent data indicates that more than 20% of adults may encounter at least one mental disorder in their lifetime. On the one hand, the advancements in…

Computation and Language · Computer Science 2024-02-05 Mihael Arcan , David-Paul Niland , Fionn Delahunty

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Computation and Language · Computer Science 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

The latest large language models (LLMs) such as ChatGPT, exhibit strong capabilities in automated mental health analysis. However, existing relevant studies bear several limitations, including inadequate evaluations, lack of prompting…

Computation and Language · Computer Science 2024-10-03 Kailai Yang , Shaoxiong Ji , Tianlin Zhang , Qianqian Xie , Ziyan Kuang , Sophia Ananiadou

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding…

Computation and Language · Computer Science 2025-11-04 He Hu , Yucheng Zhou , Juzheng Si , Qianning Wang , Hengheng Zhang , Fuji Ren , Fei Ma , Laizhong Cui , Qi Tian

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong…

Human-Computer Interaction · Computer Science 2025-08-27 Yupei Li , Shuaijie Shao , Manuel Milling , Björn W. Schuller

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

Adult neurodivergence, including Attention-Deficit/Hyperactivity Disorder (ADHD), high-functioning Autism Spectrum Disorder (ASD), and Cognitive Disengagement Syndrome (CDS), is marked by substantial symptom overlap that limits the…

Neurons and Cognition · Quantitative Biology 2026-01-23 Francesco Chiappone , Davide Marocco , Nicola Milano

Large language models (LLMs) are transforming research on machine learning while galvanizing public debates. Understanding not only when these models work well and succeed but also why they fail and misbehave is of great societal relevance.…

Computation and Language · Computer Science 2024-10-16 Julian Coda-Forno , Kristin Witte , Akshay K. Jagadish , Marcel Binz , Zeynep Akata , Eric Schulz

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Large language models (LLMs) offer significant potential in enhancing psychiatric practice, from improving diagnostic accuracy to streamlining clinical documentation and therapeutic support. However, existing evaluation resources heavily…

Computation and Language · Computer Science 2025-11-25 Aya E. Fouda , Abdelrahamn A. Hassan , Radwa J. Hanafy , Mohammed E. Fouda

Large Language Models (LLMs) have demonstrated exceptional capabilities in solving various tasks, progressively evolving into general-purpose assistants. The increasing integration of LLMs into society has sparked interest in whether they…

Computation and Language · Computer Science 2025-10-20 Yuan Li , Yue Huang , Hongyi Wang , Ying Cheng , Xiangliang Zhang , James Zou , Lichao Sun

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Mental health disorders are increasingly prevalent worldwide, creating an urgent need for innovative tools to support early diagnosis and intervention. This study explores the potential of Large Language Models (LLMs) in multimodal mental…

Computation and Language · Computer Science 2025-08-14 Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda