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Despite the widespread adoption of autoregressive language models, explainability evaluation research has predominantly focused on span infilling and masked language models. Evaluating the faithfulness of an explanation method -- how…

Computation and Language · Computer Science 2025-03-11 Sepehr Kamahi , Yadollah Yaghoobzadeh

Despite their high accuracies, modern complex image classifiers cannot be trusted for sensitive tasks due to their unknown decision-making process and potential biases. Counterfactual explanations are very effective in providing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Kamran Alipour , Aditya Lahiri , Ehsan Adeli , Babak Salimi , Michael Pazzani

Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

Machine Learning · Computer Science 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

Going beyond correlations, the understanding and identification of causal relationships in observational time series, an important subfield of Causal Discovery, poses a major challenge. The lack of access to a well-defined ground truth for…

Machine Learning · Statistics 2021-04-19 Andrew R. Lawrence , Marcus Kaiser , Rui Sampaio , Maksim Sipos

Decision-makers are faced with the challenge of estimating what is likely to happen when they take an action. For instance, if I choose not to treat this patient, are they likely to die? Practitioners commonly use supervised learning…

Machine Learning · Statistics 2018-02-02 Peter Schulam , Suchi Saria

Generating temporally coherent high fidelity video is an important milestone in generative modeling research. We make progress towards this milestone by proposing a diffusion model for video generation that shows very promising initial…

Computer Vision and Pattern Recognition · Computer Science 2022-06-24 Jonathan Ho , Tim Salimans , Alexey Gritsenko , William Chan , Mohammad Norouzi , David J. Fleet

We regularly consider answering counterfactual questions in practice, such as "Would people with diabetes take a turn for the better had they choose another medication?". Observational studies are growing in significance in answering such…

Machine Learning · Computer Science 2022-08-16 Guanglin Zhou , Lina Yao , Xiwei Xu , Chen Wang , Liming Zhu

Using observational data to estimate the effect of a treatment is a powerful tool for decision-making when randomized experiments are infeasible or costly. However, observational data often yields biased estimates of treatment effects,…

Methodology · Statistics 2022-03-01 Tobias Hatt , Stefan Feuerriegel

Counterfactual explanation is a common class of methods to make local explanations of machine learning decisions. For a given instance, these methods aim to find the smallest modification of feature values that changes the predicted…

Artificial Intelligence · Computer Science 2022-12-22 Victor Guyomard , Françoise Fessant , Thomas Guyet , Tassadit Bouadi , Alexandre Termier

Causal effects are often characterized with averages, which can give an incomplete picture of the underlying counterfactual distributions. Here we consider estimating the entire counterfactual density and generic functionals thereof. We…

Methodology · Statistics 2021-02-25 Edward H. Kennedy , Sivaraman Balakrishnan , Larry Wasserman

The lack of real-world data in clinical fields poses a major obstacle in training effective AI models for diagnostic and preventive tools in medicine. Generative AI has shown promise in increasing data volume and enhancing model training,…

Machine Learning · Computer Science 2026-02-10 Md Shahriar Kabir , Sana Alamgeer , Minakshi Debnath , Anne H. H. Ngu

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Counterfactual explanations are attracting significant attention due to the flourishing applications of machine learning models in consequential domains. A counterfactual plan consists of multiple possibilities to modify a given instance so…

Machine Learning · Computer Science 2022-04-12 Ngoc Bui , Duy Nguyen , Viet Anh Nguyen

Counterfactual explanations are one of the prominent eXplainable Artificial Intelligence (XAI) techniques, and suggest changes to input data that could alter predictions, leading to more favourable outcomes. Existing counterfactual methods…

Artificial Intelligence · Computer Science 2025-05-22 Andrei Buliga , Chiara Di Francescomarino , Chiara Ghidini , Marco Montali , Massimiliano Ronzani

Deep generative models have shown tremendous capability in data density estimation and data generation from finite samples. While these models have shown impressive performance by learning correlations among features in the data, some…

Machine Learning · Computer Science 2024-05-24 Aneesh Komanduri , Xintao Wu , Yongkai Wu , Feng Chen

Generative AI has revolutionised visual content editing, empowering users to effortlessly modify images and videos. However, not all edits are equal. To perform realistic edits in domains such as natural image or medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Thomas Melistas , Nikos Spyrou , Nefeli Gkouti , Pedro Sanchez , Athanasios Vlontzos , Yannis Panagakis , Giorgos Papanastasiou , Sotirios A. Tsaftaris

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

A common objective in the analysis of tabular data is estimating the conditional distribution (in contrast to only producing predictions) of a set of "outcome" variables given a set of "covariates", which is sometimes referred to as the…

Machine Learning · Statistics 2024-10-08 Zhuoqun Wang , Naoki Awaya , Li Ma

In recent years, diffusion models have gained popularity for their ability to generate higher-quality images in comparison to GAN models. However, like any other large generative models, these models require a huge amount of data,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Rajesh Shrestha , Bowen Xie

Constrained generative modeling is fundamental to applications such as robotic control and autonomous driving, where models must respect physical laws and safety-critical constraints. In real-world settings, these constraints rarely take…

Machine Learning · Computer Science 2026-03-10 Xiaoxuan Liang , Saeid Naderiparizi , Yunpeng Liu , Berend Zwartsenberg , Frank Wood