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Three coarse-grained models of the double-stranded DNA are proposed and compared in the context of mechanical manipulation such as twisting and various schemes of stretching. The models differ in the number of effective beads (between two…

Biomolecules · Quantitative Biology 2015-05-13 Szymon Niewieczerzał , Marek Cieplak

We demonstrate a facile technique to scratch, manipulate, and solder exfoliated flakes of layered 2D materials using a microneedle probe attached to the precision xyz manipulators under an optical microscope. We show that the probe can be…

Applied Physics · Physics 2024-01-26 Qing Rao , Guoyun Gao , Xinyu Wang , Hongxia Xue , Dong-Keun Ki

Soft stretchable materials are key for arising technologies such as stretchable electronics or batteries, smart textiles, biomedical devices, tissue engineering and soft robotics. Recent attempts to design such materials, via e.g.…

Understanding lattice deformations is crucial in determining the properties of nanomaterials, which can become more prominent in future applications ranging from energy harvesting to electronic devices. However, it remains challenging to…

The ability to control the location of nanoscale objects in liquids is essential for fundamental and applied research from nanofluidics to molecular biology. To overcome their random Brownian motion, the electrostatic fluidic trap creates…

Optomechanical manipulation of micro and nano-scale objects with laser beams finds use in a large span of multidisciplinary applications. Auxiliary nanostructuring could substantially improve performances of classical optical tweezers by…

Optics · Physics 2015-06-08 Andrey A. Bogdanov , Alexander S. Shalin , Pavel Ginzburg

We present a new concept for the separation of DNA molecules by contour length that combines a nanofluidic ratchet, nanopore translocation and pulsed fields. Using Langevin Dynamics simulations, we show that it is possible to design pulsed…

Soft Condensed Matter · Physics 2023-01-31 Le Qiao , Kai Szuttor , Christian Holm , Gary W. Slater

Microchip electrokinetic methods are capable of increasing the sensitivity of molecular assays by enriching and purifying target analytes. However, their use is currently limited to assays that can be performed under a high external…

Quantitative Methods · Quantitative Biology 2019-01-01 Xander F. van Kooten , Moran Bercovici , Govind V. Kaigala

Despite decades of research, the ultimate goal of nanotechnology--top-down manipulation of individual atoms--has been directly achieved with only one technique: scanning probe microscopy. In this Review, we demonstrate that scanning…

Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin…

Mesoscale and Nanoscale Physics · Physics 2014-03-25 Harold Kwok , Kyle Briggs , Vincent Tabard-Cossa

Suspensions of micro and nano particles made of Polystyrene, Poly(methyl methacrylate), Silicon dioxide etc. have been a standard model system to understand colloidal physics. . These systems have proved useful insights into phenomena such…

Soft Condensed Matter · Physics 2017-10-04 Praneet Prakash , Manoj Varma

Although general purpose robotic manipulators are becoming more capable at manipulating various objects, their ability to manipulate millimeter-scale objects are usually very limited. On the other hand, ultrasonic levitation devices have…

Robotics · Computer Science 2020-02-24 Jared Nakahara , Boling Yang , Joshua R. Smith

The article demonstrates a technique for fabricating a structure with the inclusion of suspended DNA threads and manipulating them using composite nanotweezers with shape memory effect. This technique could be suitable for stretching of…

We present a detailed theoretical study of the recent proposal for selective nanomanipulation of nanometric particles above a substrate using near-field optical forces [Chaumet {\it et al.} Phys. Rev. Lett. {\bf 88}, 123601 (2002)].…

Optics · Physics 2009-11-10 Patrick C. Chaumet , Adel Rahmani , Manuel Nieto-Vesperinas

Efficient capture and detection of minute amount of deoxyribonucleic acid (DNA) molecules are pivotal for an array of modern gene technologies which are widely utilized in medical, forensic and defense applications, including DNA…

Biological Physics · Physics 2018-11-19 Jianhe Guo , Kwanoh Kim , Peter Vandeventer , Donglei , Fan

This study demonstrates that the nanopore terraces constructed on a multilayer graphene sheet could be employed to con-trol the conformation and transportation of an ssDNA for nanopore sequencing. As adsorbed on a terraced graphene…

Biological Physics · Physics 2015-09-08 Wenping Lv , Jiaxi Peng , Dongsheng Xu , Renan Wu

This paper presents the technique of flex-and-flip manipulation. It is suitable for grasping thin, flexible linear objects lying on a flat surface. During the manipulation process, the object is first flexed by a robotic gripper whose…

Robotics · Computer Science 2023-04-04 Chunli Jiang , Abdullah Nazir , Ghasem Abbasnejad , Jungwon Seo

The last decade, nanopores have emerged as a new and interesting tool for the study of biological macromolecules like proteins and DNA. While biological pores, especially alpha-hemolysin, have been promising for the detection of DNA, their…

Biological Physics · Physics 2015-03-13 Ronald Kox , Stella Deheryan , Chang Chen , Nima Arjmandi , Liesbet Lagae , Gustaaf Borghs

We demonstrate high-resolution modification of suspended multi-layer graphene sheets by controlled exposure to the focused electron beam of a transmission electron microscope. We show that this technique can be used to realize, on…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Michael D. Fischbein , Marija Drndic

Semiconductor microelectronics are emerging as a powerful tool for building smart, autonomous robots too small to see with the naked eye. Yet a number of existing microrobot platforms, despite significant advantages in speed, robustness,…

Robotics · Computer Science 2024-11-15 Lucas C. Hanson , William H. Reinhardt , Scott Shrager , Tarunyaa Sivakumar , Marc Z. Miskin