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The manipulation of microparticles using optical forces has led to many applications in the life and physical sciences. To extend optical trapping towards the nano-regime, in this work we demonstrate trapping of single nanoparticles in…

In this paper we consider a physical system in which two DNA molecules braid about each other. The distance between the two molecular ends, on either side of the braid, is held at a distance much larger than supercoiling radius of the…

Soft Condensed Matter · Physics 2014-07-02 Dominic J. , Lee

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

When the DNA double helix is subjected to external forces it can stretch elastically to elongations reaching 100% of its natural length. These distortions, imposed at the mesoscopic or macroscopic scales, have a dramatic effect on…

Materials Science · Physics 2009-11-13 Ryan Barnett , Paul Maragakis , Ari Turner , Maria Fyta , Efthimios Kaxiras

The effect of electrostatic interactions on the stretching of DNA is investigated using a simple worm like chain model. In the limit of small force there are large conformational fluctuations which are treated using a self-consistent…

Soft Condensed Matter · Physics 2009-10-31 Namkyung Lee , D. Thirumalai

The interaction mechanism between a single microscopic object like a cell, a particle, a molecule, or an atom and its interacting electromagnetic field is fundamental in single-object manipulation such as optical trap and magnetic trap.…

Biological Physics · Physics 2025-03-04 Yuang Chen , Haojing Tan , Jiahua Zhuang , Yang Xu , Chen Zhang , Jiandong Feng

DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been…

Biological Physics · Physics 2015-06-02 Katherine E. Dunn

The control of strain in two-dimensional materials opens exciting perspectives for the engineering of their electronic properties. While this expectation has been validated by artificial-lattice studies, it remains elusive in the case of…

Based on our formulation of the DNA electrophoresis near a pore [P. Rowghanian and A. Y. Grosberg, Phys. Rev. E 87, 042723 (2013)], we address the electrophoretic DNA capture into a nanopore as a steady-state process of particle absorption…

Biological Physics · Physics 2013-06-20 Payam Rowghanian , Alexander Y. Grosberg

This paper aims at a comprehensive understanding on the novel elastic property of double-stranded DNA (dsDNA) discovered very recently through single-molecule manipulation techniques. A general elastic model for double-stranded biopolymers…

Soft Condensed Matter · Physics 2009-10-31 Haijun Zhou , Yang Zhang , Zhong-can Ou-Yang

Solid-state nanopore DNA sequencers present mechanical and chemical stability, reusability, and large-scale integrability. However, their development is hindered by the absence of a protein-free mechanism for controlling DNA translocation,…

Biological Physics · Physics 2026-03-17 Tomoki Ohkubo

Self-positioned nanomembranes such as rolled-up tubes and wrinkled thin films have been potential systems for a variety of applications and basic studies on elastic properties of nanometer-thick systems. Although there is a clear driving…

Mesoscale and Nanoscale Physics · Physics 2014-07-23 Peter Cendula , Angelo Malachias , Christoph Deneke , Suwit Kiravittaya , Oliver G. Schmidt

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

In this paper we document a novel laboratory experimental platform for non-contact planar manipulation (positioning) of millimeter-scale objects using acoustic pressure. The manipulated objects are either floating on a water surface or…

Systems and Control · Computer Science 2020-11-13 Josef Matouš , Adam Kollarčík , Martin Gurtner , Tomáš Michálek , Zdeněk Hurák

The interaction between light and matter can be controlled efficiently by structuring materials at a length scale shorter than the wavelength of interest. With the goal to build optical devices that operate at the nanoscale, plasmonics has…

Optics · Physics 2021-05-06 Na Liu , Tim Liedl

In this paper, a novel architecture of electro-optical neural networks based on the time-stretch method is proposed and numerically simulated. By stretching time-domain ultrashort pulses, multiplications of large scale weight matrices and…

Signal Processing · Electrical Eng. & Systems 2019-09-18 Yubin Zang , Minghua Chen , Sigang Yang , Hongwei Chen

Recent advances in nanotechnologies have prompted the need for tools to accurately and non invasively manipulate individual nanoobjects. Among the possible strategies, optical forces have been widely used to enable nano optical tweezers…

Versatile manipulation of nano- and microobjects underlies the optomechanics and a variety of its applications in biology, medicine, and lab-on-a-chip platforms. For flexible tailoring optical forces, as well as for extraordinary…

Switchable elements are key components of dynamic technological and biological systems, enabling reversible transitions between well-defined states. Here, we present a DNA origami-based, mechanically bistable snap-through mechanism that can…