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We study the electromechanical transduction in nanoelectromechanical actuators and show that the differences in scaling for electrical and mechanical effects lead to an overall non-trivial scaling behavior. In particular, the previously…

Applied Physics · Physics 2020-07-01 Konstantinos Tsoukalas , Babak Vosoughi Lahijani , Søren Stobbe

Dielectrophoretic trapping of six different DNA fragments, sizes varying from the 27 to 8416 bp, has been studied using confocal microscopy. The effect of the DNA length and the size of the constriction between nanoscale fingertip…

Noncontact particle manipulation (NPM) technology has significantly extended mankind's analysis capability into micro and nano scale, which in turn greatly promoted the development of material science and life science. Though NPM by means…

Robotics · Computer Science 2022-08-23 Mingyue Wang , Jiaqi Li , Yuyu Jia , Zhenhuan Sun , Yuhang Liu , Teng Li , Song Liu

Electroporation is a physical method to induce the uptake of therapeutic drugs and DNA, by eukaryotic cells and tissues. The phenomena behind electro-mediated membrane permeabilization to plasmid DNA have been shown to be significantly more…

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

The translocation of a short DNA fragment through a nanopore is addressed when the perforated membrane contains an embedded electrode. Accurate numerical solutions of the coupled Poisson, Nernst-Planck, and Stokes equations for a realistic,…

Soft Condensed Matter · Physics 2017-06-29 Thomas Töws , Peter Reimann

Manipulating elasto-plastic objects remains a significant challenge due to severe self-occlusion, difficulties of representation, and complicated dynamics. This work proposes a novel framework for elasto-plastic object manipulation with a…

Robotics · Computer Science 2025-05-26 Zhen Zhang , Xiangyu Chu , Yunxi Tang , Lulu Zhao , Jing Huang , Zhongliang Jiang , K. W. Samuel Au

Quantum vacuum forces dictate the interaction between individual atoms and dielectric surfaces at nanoscale distances. For example, their large strengths typically overwhelm externally applied forces, which makes it challenging to…

Quantum Physics · Physics 2015-06-17 D. E. Chang , K. Sinha , J. M. Taylor , H. J. Kimble

Controlled movement and manipulation of magnetic micro and nanostructures using magnetic forces can give rise to important applications in biomedecine, diagnostics and immunology. We report controlled magnetophoresis and stretching, in…

Soft Condensed Matter · Physics 2009-11-13 B. Babić , R. Ghai , K. Dimitrov

Non-invasive optical manipulation of particles has emerged as a powerful and versatile tool for biological study and nanotechnology. In particular, trapping and rotation of cells, cell nuclei and sub-micron particles enables unique…

Trapping nanoscopic objects to observe their dynamic behaviour for extended periods of time is an ongoing quest. Particularly, sub-100nm transparent objects are hard to catch and most techniques rely on immobilisation or transient diffusion…

Quantitative Methods · Quantitative Biology 2017-01-13 Maria Dienerowitz , Thomas Heitkamp , Thomas Gottschall , Jens Limpert , Michael Borsch

Genetic information is stored in a linear sequence of base-pairs; however, thermal fluctuations and complex DNA conformations such as folds and loops make it challenging to order genomic material for in vitro analysis. In this work, we…

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

Soft Condensed Matter · Physics 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

Solid-state nanopores are emerging platforms for single-molecule protein sequencing due to their tolerance to hash physiology environment and compatibility with different electrical and optical detection methods. However, they suffer from…

Applied Physics · Physics 2024-01-05 Yingqi Zhao , Aliaksandr Hubarevich , Jian-An Huang , Francesco De Angelis

Particles that can be trapped in optical tweezers range from tens of microns down to tens of nanometres in size. Interestingly, this size range includes large macromolecules. We show experimentally, in agreement with theoretical…

Optics · Physics 2007-05-23 W. Singer , T. A. Nieminen , N. R. Heckenberg , H. Rubinsztein-Dunlop

Controlling the transport, trapping, and filtering of nanoparticles is important for many applications. By virtue of their weak response to gravity and their thermal motion, various physical mechanisms can be exploited for such operations…

Materials Science · Physics 2016-11-03 Rasoul Alaee , Muamer Kadic , Carsten Rockstuhl , Ali Passian

Thermalcycler were extensively used machine for amplify DNA sample. One of the major problems in the working time was that it spent most of time for cooling and heating. In order to improve the efficient, this study presented a novel method…

Other Computer Science · Computer Science 2007-11-29 Ch. -Heng Chien , Hui-Min Yu

The exciting field of stretchable electronics (SE) promises numerous novel applications, particularly in-body and medical diagnostics devices. However, future advanced SE miniature devices will require high-density, extremely stretchable…

Instrumentation and Detectors · Physics 2017-09-14 Salman Shafqat , Johan P. M. Hoefnagels , Angel Savov , Shivani Joshi , Ronald Dekker , Marc G. D. Geers

Heterogeneous nanoscale particles released by cells known as extracellular vesicles (EVs) are actively investigated for early disease detection1, monitoring2, and advanced therapeutics3. Due to their extremely small size, the stable…

Optics · Physics 2024-01-26 Chuchuan Hong , Justus C. Ndukaife

Nanodiamonds (NDs) are key materials for building nanoscale quantum sensing, imaging and communication devices. Scalable configuration of single NDs on heterogeneous platforms, forming photonic quantum source arrays, will be an essential…