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Undulation of infection levels, usually called waves, are not well understood. In this paper we propose a mathematical model that exhibits undulation and decay towards a stable state. The model is a re-interpretation of the original…

Populations and Evolution · Quantitative Biology 2022-06-08 Niko Sauer

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Developing robust, quantitative methods to optimize resource allocations in response to epidemics has the potential to save lives and minimize health care costs. In this paper, we develop and apply a computationally efficient algorithm that…

Quantitative Methods · Quantitative Biology 2015-06-22 Edwin C. Yuan , David L. Alderson , Sean Stromberg , Jean M. Carlson

In this paper, we consider a discrete-time stochastic SIR model, where the transmission rate and the true number of infectious individuals are random and unobservable. An advantage of this model is that it permits us to account for random…

Physics and Society · Physics 2024-01-30 Katia Colaneri , Camilla Damian , Rüdiger Frey

Some recent works reveal that there are models of differential equations for the mean and variance of infected individuals that reproduce the SIS epidemic model at some point. This stochastic SIS epidemic model can be interpreted as a…

Populations and Evolution · Quantitative Biology 2020-08-07 Oğul Esen , Eduardo Fernández-Saiz , Cristina Sardón , Marcin Zając

Susceptibility governs the dynamics of contagion. The classical SIR model is one of the simplest compartmental models of contagion spread, assuming a single shared susceptibility level. However, variation in susceptibility over a population…

Populations and Evolution · Quantitative Biology 2020-09-22 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua Weitz , Andrew A. Peterson

The Susceptible-Exposed-Infectious-Recovered (SEIR) model is applied in several countries to ascertain the spread of the coronavirus disease 2019 (COVID-19). We consider discrete-time SEIR epidemic model in a closed system which does not…

Dynamical Systems · Mathematics 2021-05-04 U. A. Rozikov , S. K. Shoyimardonov

Most epidemic processes on networks can be modelled by a compartmental model, that specifies the spread of a disease in a population. The corresponding compartmental graph describes how the viral state of the nodes (individuals) changes…

Physics and Society · Physics 2023-11-29 Massimo A. Achterberg , Piet Van Mieghem

In this article, we introduce an infinite-dimensional deterministic SIS model which takes into account the heterogeneity of the infections and the social network among a large population. We study the long-time behavior of the dynamic. We…

Dynamical Systems · Mathematics 2020-06-16 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

In this work we study the stability properties of the equilibrium points of deterministic epidemic models with nonconstant population size. Models with nonconstant population have been studied in the past only in particular cases, two of…

Optimization and Control · Mathematics 2022-02-25 Florin Avram , Rim Adenane , Lasko Basnarkov , Gianluca Bianchin , Dan Goreac , Andrei Halanay

We introduce an interacting particle system that models the spread of an epidemic in terms of heterogeneous diffusive dynamics, rather than exogenous contact and transmission rates at the population level as in classical compartmental…

Probability · Mathematics 2026-05-20 Eliana Fausti , Andreas Sojmark

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

Over the past several decades there has been a proliferation of epidemiological models with ordinary derivatives replaced by fractional derivatives in an an-hoc manner. These models may be mathematically interesting but their relevance is…

Populations and Evolution · Quantitative Biology 2016-03-31 C. N. Angstmann , B. I. Henry , A. V. McGann

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

A class of multiple-timescale asymptotic solutions to the equations of the susceptible-infected-recovered (SIR) model is presented for the case of high basic reproduction number, with the inverse of the latter employed as the expansion…

Populations and Evolution · Quantitative Biology 2025-12-25 Oleg B. Shiryaev

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov

We investigate the global behaviour of a SIRI epidemic model with distributed delay and relapse. From the theory of functional differential equations with delay, we prove that the solution of the system is unique, bounded, and positive, for…

Classical Analysis and ODEs · Mathematics 2019-08-12 Abdelhai Elazzouzi , Abdesslem Lamrani Alaoui , Mouhcine Tilioua , Delfim F. M. Torres

We study the minimum eradication time problem for controlled Susceptible-Infected-Recovered (SIR) epidemic models that incorporate vaccination control and time-varying infected and recovery rates. Unlike the SIR model with constant rates,…

Analysis of PDEs · Mathematics 2023-11-27 Jiwoong Jang , Yeoneung Kim

Vaccination campaigns have both direct and indirect effects that act to control an infectious disease as it spreads through a population. Indirect effects arise when vaccinated individuals block disease transmission in any infection chains…

Populations and Evolution · Quantitative Biology 2024-05-08 Lixin Lin , Homayoun Hamedmoghadam , Robert Shorten , Lewi Stone
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