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In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

The SIR(D) epidemiological model is defined through a system of transcendental equations, not solvable by elementary functions. In the present paper those equations are successfully replaced by approximate ones, whose solutions are given…

Populations and Evolution · Quantitative Biology 2021-01-06 Ignazio Lazzizzera

To understand the impact of vaccination, we consider a SIVR (susceptible-infected-vaccinated-recovered) model which combines impulsive vaccination into the classical SIR model. The final size is firstly defined and estimated, and then the…

Populations and Evolution · Quantitative Biology 2024-10-29 Phyu Phyu Win , Zhigui Lin , Mengyun Zhang

The SIR pandemic model suffers from an unrealistic assumption: The rate of removal from the infectious class of individuals is assumed to be proportional to the number of infectious individuals. This means that a change in the rate of…

Populations and Evolution · Quantitative Biology 2021-02-23 Paul A. Reiser

We present an exact analytical solution to a one-dimensional model of the Susceptible-Infected-Recovered (SIR) epidemic type, with infection rates dependent on nearest-neighbor occupations. We use a quantum mechanical approach, transforming…

Statistical Mechanics · Physics 2015-05-30 H. Thomas Williams , Irina Mazilu , Dan Mazilu

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

An age-dependent SIR model is considered with the aim to develop a state-feedback vaccination law in order to eradicate a disease. A dynamical analysis of the system is performed using the principle of linearized stability and shows that,…

Optimization and Control · Mathematics 2022-05-18 Candy Sonveaux , Joseph J. Winkin

We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

Optimization and Control · Mathematics 2022-01-26 Marcel Fang , Pierre-Alexandre Bliman

We present a derivation of the classical SIR model through a mean-field approximation from a discrete version of SIR. We then obtain a hyperbolic forward Kolmogorov equation, and show that its projected characteristics recover the standard…

Populations and Evolution · Quantitative Biology 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

In a collection of particles performing independent random walks on $\mathbb Z^d$ we study the spread of an infection with SIR dynamics. Susceptible particles become infected when they meet an infected particle. Infected particles heal and…

Probability · Mathematics 2022-09-14 Duncan Dauvergne , Allan Sly

The SIR model is the cornerstone model for mathematical epidemiology, explaining key epidemic features such as the second-order transition between disease-free and epidemic states, the initial exponential growth of outbreaks or the…

Populations and Evolution · Quantitative Biology 2026-03-20 Santiago Lamata-Otín , Alex Arenas , Jesús Gómez-Gardeñes , David Soriano-Paños

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model. Through the use of a normal form coordinate transform, we are able to analytically derive the stochastic center manifold along with the…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Eric Forgoston , Lora Billings , Ira B. Schwartz

We introduce a stochastic SIR-type partial differential equation model incorporating random diffusion, reinfection, vital dynamics, and a randomly varying transmission rate. For the associated random dynamical system, we prove the existence…

The SIR model is a classical model characterizing the spreading of infectious diseases. This model describes the time-dependent quantity changes among Susceptible, Infectious, and Recovered groups. By introducing space-depend effects such…

Quantitative Methods · Quantitative Biology 2024-09-18 Md Abu Talha , Yongjia Xu , Shan Zhao , Weihua Geng

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

Populations and Evolution · Quantitative Biology 2020-06-19 Christian Gourieroux , Joann Jasiak

Let S,I and R be susceptible, infected and recovered populations in a city affected by an epidemic. The SIR model of Lee, Liu, Tembine, Li and Osher, \emph{SIAM J. Appl. Math.},~81, 190--207, 2021 of the spatiotemoral spread of epidemics is…

Numerical Analysis · Mathematics 2024-01-05 Michael V. Klibanov , Jingzhi Li , Zhipeng Yang

We propose and solve an optimal vaccination problem within a deterministic compartmental model of SIRS type: the immunized population can become susceptible again, e.g.\ because of a not complete immunization power of the vaccine. A social…

Optimization and Control · Mathematics 2022-06-08 Salvatore Federico , Giorgio Ferrari , Maria-Laura Torrente