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SIRS models capture transmission dynamics of infectious diseases for which immunity is not lifelong. Extending these models by a W compartment for individuals with waning immunity, the boosting of the immune system upon repeated exposure…

Populations and Evolution · Quantitative Biology 2022-01-19 Richmond Opoku-Sarkodie , Ferenc A. Bartha , Mónika Polner , Gergely Röst

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

A plethora of prediction models of SARS-CoV-2 pandemic were proposed in the past. Prediction performances not only depend on the structure and features of the model, but also on its parametrization. Official databases are often biased due…

Populations and Evolution · Quantitative Biology 2021-09-27 Yuri Kheifetz , Holger Kirsten , Markus Scholz

We study the SIR ("susceptible, infected, removed/recovered") model on directed graphs with heterogeneous transmission probabilities within the message-passing approximation. We characterize the percolation transition, predict cluster size…

Physics and Society · Physics 2021-12-01 Christoph Widder , Tanja Schilling

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

Optimization and Control · Mathematics 2021-06-29 David I. Ketcheson

This paper presents several simple linear vaccination-based control strategies for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , S. Alonso-Quesada

In this manuscript, we develop a mobility-based Susceptible-Infectious-Recovered (SIR) model to elucidate the dynamics of pandemic propagation. While traditional SIR models within the field of epidemiology aptly characterize transitions…

Dynamical Systems · Mathematics 2025-01-16 Ciana Applegate , Jiaxu Li , Dan Han

We study the spread of discrete-time epidemics over arbitrary networks for well-known propagation models, namely SIS (susceptible-infected-susceptible), SIR (susceptible-infected-recovered), SIRS (susceptible-infected-recovered-susceptible)…

Social and Information Networks · Computer Science 2016-10-03 Navid Azizan Ruhi , Hyoung Jun Ahn , Babak Hassibi

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

Throughout human history, epidemics have been a constant presence. Understanding their dynamics is essential to predict scenarios and make substantiated decisions. Mathematical models are powerful tools to describe an epidemic behavior.…

Systems and Control · Electrical Eng. & Systems 2024-07-26 Walter HMendes aselein , Diego Eckhard

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

The COVID-19 pandemic highlighted the need to improve the modeling, estimation, and prediction of how infectious diseases spread. SEIR-like models have been particularly successful in providing accurate short-term predictions. This study…

Populations and Evolution · Quantitative Biology 2024-12-31 Jorge P. Zubelli , Jennifer Loria , Vinicius V. L. Albani

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

We study an optimal control problem for a non-autonomous SEIRS model with incidence given by a general function of the infective, the susceptible and the total population, and with vaccination and treatment as control variables. We prove…

Optimization and Control · Mathematics 2018-06-13 Joaquim P. Mateus , Paulo Rebelo , Silvério Rosa , César M. Silva , Delfim F. M. Torres

We consider the optimal allocation of (perfect) vaccine in an heterogeneous SIS model. Using a coupling approach, we explain how different models for the heterogeneity of the population lead to the same Pareto frontier in the cost/loss…

Probability · Mathematics 2025-09-08 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

The Susceptible-Infected-Susceptible (SIS) model is a widely used model for the spread of information and infectious diseases, particularly non-immunizing ones, on a graph. Given a highly contagious disease, a natural question is how to…

Machine Learning · Computer Science 2025-06-19 Sepehr Elahi , Paula Mürmann , Patrick Thiran

Our study is based on an epidemiological compartmental model, the SIRS model. In the SIRS model, each individual is in one of the states susceptible (S), infected(I) or recovered (R), depending on its state of health. In compartment R, an…

Populations and Evolution · Quantitative Biology 2023-05-10 Michael Bestehorn , Thomas M. Michelitsch

In this work, we study the epidemic SIR model on a system which takes into consideration face-to-face interaction networks. This approach has been used as prototype to describe people interactions in different kinds of social organizations…

This paper studies algorithmic strategies to effectively reduce the number of infections in susceptible-infected-recovered (SIR) epidemic models. We consider a Markov chain SIR model and its two instantiations in the deterministic SIR…

Optimization and Control · Mathematics 2020-11-24 Yuhao Yi , Liren Shan , Philip E. Paré , Karl H. Johansson
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