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Automated vascular segmentation on optical coherence tomography angiography (OCTA) is important for the quantitative analyses of retinal microvasculature in neuroretinal and systemic diseases. Despite recent improvements, artifacts continue…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Yih-Cherng Lee , Ling Yeung

Optical coherence tomography angiography (OCTA) shows its great importance in imaging microvascular networks by providing accurate 3D imaging of blood vessels, but it relies upon specialized sensors and expensive devices. For this reason,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Zhuangzhuang Chen , Hualiang Wang , Chubin Ou , Xiaomeng Li

Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…

Modern optical coherence tomography (OCT) devices provide volumetric images with micrometer-scale spatial resolution and a temporal resolution beyond video rate. In this work, we analyze an OCT-based prototypical tracking system which…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Matthias Schlüter , Lukas Glandorf , Johanna Sprenger , Martin Gromniak , Maximilian Neidhardt , Thore Saathoff , Alexander Schlaefer

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Intracoronary Optical Coherence Tomography (OCT) enables high-resolution visualization of coronary vessel anatomy but presents challenges due to noise, imaging artifacts, and complex tissue structures. This paper proposes a fully automated…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Amal Lahchim , Lambros Athanasiou

Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. Therefore it is commonly used in the diagnosis of retinal diseases associated with edema in and under…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Morgan Heisler , Sieun Lee , Gavin Ding , Marinko V. Sarunic , Mirza Faisal Beg

Objective. A detailed analysis of the corneal retardation time $\tau$ as a highly related parameter to the intraocular pressure (IOP), and its plausible role as an indicator of ocular hypertension disease. Approach. A simple theoretical…

Biological Physics · Physics 2023-12-08 Oscar del Barco , Francisco J. Avila , Concepción Marcellán , Laura Remón

Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Julian Lo , Morgan Heisler , Vinicius Vanzan , Sonja Karst , Ivana Zadro Matovinovic , Sven Loncaric , Eduardo V. Navajas , Mirza Faisal Beg , Marinko V. Sarunic

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

The accurate quantification of blood flow in aortoiliac arteries is challenging but clinically relevant because local flow patterns can influence atherosclerotic disease. To investigate the feasibility and clinical application of…

High-speed digital holography reveals local blood flow contrasts in the eye fundus through deterministic signal analysis, leveraging a forward scattering model of dynamically diffused light. This approach enables the estimation of absolute…

Instrumentation and Detectors · Physics 2025-05-14 Zacharie Auray , Yann Fischer , Olivier Martinache , Michael Atlan

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Optical coherence tomography angiography (OCTA) has drawn numerous attentions in ophthalmology. However, its data acquisition is time-consuming, because it is based on temporal-decorrelation principle thus requires multiple repeated…

Medical Physics · Physics 2019-10-15 Jianlong Yang , Peng Liu , Lixin Duan , Yan Hu , Jiang Liu

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Optical coherence tomography angiography (OCTA) is a new imaging modality to visualize retinal microvasculature and has been readily adopted in clinics. High-resolution OCT angiograms are important to qualitatively and quantitatively…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Yuyan Ruan , Dawei Yang , Ziqi Tang , An Ran Ran , Carol Y. Cheung , Hao Chen

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

Cardiac CT is often used clinically in electrophysiology to evaluate cardiac morphology. One such case is to evaluate patients with Atrial Fibrillation (AF). AF can cause regions of slow blood flow and blood stasis through the left atrial…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Lauren M. Severance , Andrew M. Kahn , Juan C. del Alamo , Elliot R. McVeigh