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At the present time Optical Coherence Tomography (OCT) is among the most commonly used non-invasive imaging methods for the acquisition of large volumetric scans of human retinal tissues and vasculature. To resolve decisive information from…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 D. Sitenko , B. Boll , C. Schnörr

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…

Medical Physics · Physics 2021-10-22 Alex Ce Zhang , Yu-Hwa Lo

This study is to characterize reflectance profiles of retinal blood vessels in optical coherence tomography (OCT), and to validate these vascular features to guide artery-vein classification in OCT angiography (OCTA) of human retina.…

Tissues and Organs · Quantitative Biology 2022-02-08 Tobiloba Adejumo , Tae-Hoon Kim , David Le , Taeyoon Son , Guangying Ma , Xincheng Yao

Full-field swept-source optical coherence tomography (FF-SS-OCT) and laser Doppler holography (LDH) are two holographic imaging techniques presenting unique capabilities for ophthalmology. We report on interlaced FF-SS-OCT and LDH imaging…

Medical Physics · Physics 2022-03-01 Léo Puyo , Hendrik Spahr , Clara Pfäffle , Gereon Hüttmann , Dierck Hillmann

Segmenting specific targets or biomarkers is necessary to analyze optical coherence tomography angiography (OCTA) images. Previous methods typically segment all the targets in an OCTA sample, such as retinal vessels (RVs). Although these…

Machine Learning · Computer Science 2024-03-21 Xinrun Chen , Chengliang Wang , Haojian Ning , Shiying Li , Mei Shen

Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) are key diagnostic tools for clinical evaluation and management of retinal diseases. Compared to traditional OCT, OCTA provides richer microvascular…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Renzhi Tian , Jinjie Wang , Wei Yang , Weizhen Li , Haoran Chen , Yiran Zhu , Chengchang Pan , Honggang Qi

Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry…

Medical Physics · Physics 2021-08-10 Léo Puyo , Michel Paques , Michael Atlan

Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here investigate separating the different contributions to the power…

Medical Physics · Physics 2021-06-02 Léo Puyo , Michel Paques , Mathias Fink , José-Alain Sahel , Michael Atlan

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality that allows micron-level resolution to visualize the retinal microvasculature. The retinal vessel segmentation in OCTA images is still an open problem,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Mingchao Li , Yerui Chen , Weiwei Zhang , Qiang Chen

Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Lennart Husvogt , Stefan B. Ploner , Siyu Chen , Daniel Stromer , Julia Schottenhamml , A. Yasin Alibhai , Eric Moult , Nadia K. Waheed , James G. Fujimoto , Andreas Maier

Optical Coherence Tomography Angiography (OCTA) is a crucial tool in the clinical screening of retinal diseases, allowing for accurate 3D imaging of blood vessels through non-invasive scanning. However, the hardware-based approach for…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Shuhan Li , Dong Zhang , Xiaomeng Li , Chubin Ou , Lin An , Yanwu Xu , Kwang-Ting Cheng

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

The eye offers a unique opportunity for non-invasive exploration of cardiovascular diseases. Optical angiography in the retina requires sensitive measurements, which hinders conventional full-field laser Doppler imaging schemes. To overcome…

Medical Physics · Physics 2018-09-18 L. Puyo , M. Paques , M. Fink , J. -A. Sahel , M. Atlan

Optical coherence tomography (OCT) is a non-invasive imaging technique widely used for ophthalmology. It can be extended to OCT angiography (OCT-A), which reveals the retinal vasculature with improved contrast. Recent deep learning…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Can Cui , Hao Li , Kathleen E. Larson , Yuankai K. Tao , Ipek Oguz

One of the greatest needs in modern ophthalmology is access to the eye choroid in vivo. Without it, it is difficult to introduce new therapies and to understand most of the pathological changes in the eye, because of the total blood flow in…

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

A comprehensive assessment of retinal health demands reliable and precise methods to measure localized blood perfusion. Despite considerable advancements in imaging techniques, such as indocyanine green and fluorescein angiography, along…

Medical Physics · Physics 2024-03-15 Michael Atlan

Optical Coherence Tomography Angiography (OCTA) is a promising tool for detecting Alzheimer's disease (AD) by imaging the retinal microvasculature. Ophthalmologists commonly use region-based analysis, such as the ETDRS grid, to study OCTA…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Shouyue Liu , Jinkui Hao , Yanwu Xu , Huazhu Fu , Xinyu Guo , Jiang Liu , Yalin Zheng , Yonghuai Liu , Jiong Zhang , Yitian Zhao